Results 71 to 80 of about 86,215 (260)
Crystal structure and enzymology of solanum tuberosum inositol tris/tetrakisphosphate kinase 1 (StITPK1) [PDF]
, 2023 Inositol phosphates and their pyrophosphorylated derivatives are responsive to the phosphate supply and are agents of phosphate homeostasis and other aspects of physiology. It seems likely that the enzymes that interconvert these signals work against the
Brearley, Charles A +7 more
core +5 more sources
Inositol Pyrophosphate Pyrotechnics [PDF]
Cell Metabolism, 2007 Physiologic roles of highly phosphorylated inositol phosphates, including those containing pyrophosphate groups, have been the focus of much recent interest. In the April 6, 2007 issue of Science, two papers (Lee et al., 2007; Mulugu et al., 2007) demonstrate the occurrence of a novel inositol pyrophosphate molecule in yeast and elucidate its role in ...
Solomon H. Snyder +2 more
openaire +3 more sources
Inositol pyrophosphates regulate RNA polymerase I-mediated rRNA transcription in Saccharomyces cerevisiae. [PDF]
Biochem J, 2015 Thota SG +4 more
europepmc +3 more sources
bioRxiv, 2022 Technical challenges have to date prevented a complete profiling of the levels of myo-inositol phosphates (InsPs) and pyrophosphates (PP-InsPs) in mammalian tissues.
Danye Qiu +10 more
semanticscholar +1 more source
Inositol pyrophosphates promote MYC polyubiquitination by FBW7 to regulate cell survival.
Biochemical Journal, 2021 The transcription factor MYC regulates cell survival and growth, and its level is tightly controlled in normal cells. We report that serine pyrophosphorylation - a posttranslational modification triggered by inositol pyrophosphate signaling molecules ...
Padmavathi Lolla +4 more
semanticscholar +1 more source
Structural insight into inositol pyrophosphate turnover [PDF]
Advances in Biological Regulation, 2013 The diphosphoinositol polyphosphates ("inositol pyrophosphates"; PP-InsPs) regulate many cellular processes in eukaryotes, including stress responses, apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, telomere maintenance, insulin signaling and neutrophil activation.
Huanchen Wang +2 more
openaire +3 more sources
Inositol pyrophosphates modulate cell cycle independently of alteration in telomere length [PDF]
, 2016 Synthesis of inositol pyrophosphates through activation of Kcs1 plays an important role in the signalling response required for cell cycle progression after mating pheromone arrest. Overexpression of Kcs1 doubled the level of inositol pyrophosphates when
Azevedo +25 more
core +1 more source
mBio, 2023 Inositol pyrophosphate 1,5-IP8 is a signaling molecule that regulates phosphate and polyphosphate homeostasis in the fission yeast Schizosaccharomyces pombe. 1,5-IP8 levels are dictated by a balance between the Asp1 kinase domain that converts 5-IP7 to 1,
Ana M. Sanchez +4 more
doaj +1 more source
Anharmonicity and structural phase transition in the Mott insulator Cu$_2$P$_2$O$_7$ [PDF]
Physical Review B 108.10 (2023): 104104, 2023 Ab initio investigations of structural, electronic, and dynamical properties of the high-temperature $\beta$ phase of copper pyrophosphate were performed using density functional theory. The electronic band structure shows the Mott insulating state due to electron correlations in copper ions. By calculating phonon dispersion relations, the soft mode at
arxiv +1 more source
Development of a homogenous high-throughput assay for inositol hexakisphosphate kinase 1 activity. [PDF]
PLoS ONE, 2017 Inositol pyrophosphates have been implicated in a wide range of cellular processes. Inositol hexakisphosphate kinase 1 catalyzes the pyrophosphorylation of inositol hexakisphosphate into inositol 5-diphospho-1,2,3,4,6-pentakisphosphate which is important
Michael Wormald +4 more
doaj +1 more source