Results 1 to 10 of about 336,475 (260)
Insulin-Like Growth Factor-1 and Neuroinflammation [PDF]
Frontiers in Aging Neuroscience, 2017 Insulin-like growth factor-1 (IGF-1) effects on aging and neurodegeneration is still controversial. However, it is widely admitted that IGF-1 is involved in the neuroinflammatory response.
Jose L. Labandeira-Garcia +8 more
doaj +3 more sources
Insulin-like growth factor-1/insulin-like growth factor-1 receptor signalling in macrophages facilitates recovery from acute lung injury [PDF]
Annals of MedicineBackground No effective treatment strategy for acute respiratory distress syndrome (ARDS) has been established. Conflicting reports on the effects of insulin-like growth factor (IGF)-1 stimulation and the inhibition of IGF-1 receptor (IGF-1R) signalling ...
Miyuki Niisato +5 more
doaj +2 more sources
Doxorubicin impairs the insulin-like growth factor-1 system and causes insulin-like growth factor-1 resistance in cardiomyocytes. [PDF]
PLoS ONE, 2015 Insulin-like growth factor-1 (IGF-1) promotes the survival of cardiomyocytes by activating type 1 IGF receptor (IGF-1R). Within the myocardium, IGF-1 action is modulated by IGF binding protein-3 (IGFBP-3), which sequesters IGF-1 away from IGF-1R.
Patrizia Fabbi +11 more
doaj +6 more sources
Interoceptive Information of Physical Vigor Through Circulating Insulin‐Like Growth Factor 1 [PDF]
FASEB BioAdvancesThe brain relies on interoceptive feedback signals to regulate bodily functions. Female mice with low serum IGF‐1 levels (LID mice) exhibit reduced spontaneous running compared to control females, an effect not seen in males.
Jonathan A. Zegarra‐Valdivia +6 more
doaj +2 more sources
Research in Pharmaceutical Sciences, 2018 Insulin-like growth factor binding protein-3 (IGFBP-3) is a vital protein exist in circulation which interacts with high affinity to insulin-like growth factor (IGFs) altering their activities.
Elham Jafari +6 more
doaj +4 more sources
Insulin-like growth factor-1 (IGF-1) empowering tendon regenerative therapies [PDF]
Frontiers in Bioengineering and BiotechnologyTendon injury is one of the most common musculoskeletal disorders that severely affect patients’ daily lives. Unfortunately, naturally healed tendons exhibit poor quality, as they have very limited regenerative ability.
Mingming Wang +4 more
doaj +2 more sources
The signaling landscape of insulin-like growth factor 1. [PDF]
J Biol ChemThe sheer amplitude of biological actions of insulin-like growth factor I (IGF-1) affecting all types of cells in all tissues suggests a vast signaling landscape for this ubiquitous humoral signal. While the canonical signaling pathways primarily involve the Ras/MAPK and PI3K/AKT cascades, the evolutionary conservation of insulin-like peptides (ILPs ...
Khan MZ, Zugaza JL, Torres Aleman I.
europepmc +3 more sources
Insulin-like growth factor-1 and zinc
Turkish Journal of Hematology, 2008 Nejat Akar
doaj +2 more sources
Iraqi Journal of Chemical and Petroleum Engineering, 2023 Insulin like growth factor-1 has metabolic and growth-related roles all over the body and is strongly associated and regulated by growth hormone. It is produced by almost any type of tissue, especially the liver.
Athraa F. Hasan +2 more
doaj +1 more source
Insulin-like Growth Factor-1 [PDF]
Current Opinion in Gastroenterology, 2012 Strange, disturbing quality to subjects’ dream life. Difficulty concentrating. Headache in the forehead. Nasal congestion. Cramping abdominal pain associated with diarrhea or stool. Constipation with ineffectual urging. Strong uterine cramping with the menses. Premenstrual breast tenderness and swelling. Nausea. An aversion to chocolate and sweets.
Sarah F, Bortvedt, P Kay, Lund
openaire +3 more sources