Insulin-Like Growth Factor-1 and Neuroinflammation
Frontiers in Aging Neuroscience, 2017 Insulin-like growth factor-1 (IGF-1) effects on aging and neurodegeneration is still controversial. However, it is widely admitted that IGF-1 is involved in the neuroinflammatory response.
Jose L. Labandeira-Garcia +8 more
doaj +2 more sources
Insulin-like growth factor 1 stimulates the angiogenic activity of adipose tissue–derived microvascular fragments [PDF]
Journal of Tissue Engineering, 2019 Angiogenesis in adipose tissue is promoted by insulin-like growth factor 1 signaling. We analyzed whether this regulatory mechanism also improves the angiogenic activity of adipose tissue–derived microvascular fragments.
Matthias W Laschke +5 more
doaj +2 more sources
Insulin-like growth factor-1 (IGF-1) empowering tendon regenerative therapies [PDF]
Frontiers in Bioengineering and BiotechnologyTendon injury is one of the most common musculoskeletal disorders that severely affect patients’ daily lives. Unfortunately, naturally healed tendons exhibit poor quality, as they have very limited regenerative ability.
Mingming Wang +4 more
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Development of real-time reverse transcription polymerase chain reaction assays to quantify insulin-like growth factor receptor and insulin receptor expression in equine tissue [PDF]
Onderstepoort Journal of Veterinary Research, 2013 The insulin-like growth factor system (insulin-like growth factor 1, insulin-like growth factor 2, insulin-like growth factor 1 receptor, insulin-like growth factor 2 receptor and six insulin-like growth factor-binding proteins) and insulin are essential
Stephen B. Hughes +3 more
doaj +3 more sources
Iraqi Journal of Chemical and Petroleum Engineering, 2023 Insulin like growth factor-1 has metabolic and growth-related roles all over the body and is strongly associated and regulated by growth hormone. It is produced by almost any type of tissue, especially the liver.
Athraa F. Hasan +2 more
doaj +1 more source
Insulin-Like Growth Factor 1 (IGF-1) Signaling in Glucose Metabolism in Colorectal Cancer
International Journal of Molecular Sciences, 2021 Colorectal cancer (CRC) is one of the most common aggressive carcinoma types worldwide, characterized by unfavorable curative effect and poor prognosis.
A. Kasprzak
semanticscholar +1 more source
Insulin-Like Growth Factor-1 (IGF-1) and Its Monitoring in Medical Diagnostic and in Sports
Biomolecules, 2021 Insulin-like growth factor-1 (IGF-1) is the principal mediator of growth hormone (GH), plays a crucial role in promoting cell growth and differentiation in childhood and continues to have an anabolic effect in adults.
Julian Bailes, Mikhail Soloviev
semanticscholar +1 more source
Doxorubicin impairs the insulin-like growth factor-1 system and causes insulin-like growth factor-1 resistance in cardiomyocytes. [PDF]
PLoS ONE, 2015 Insulin-like growth factor-1 (IGF-1) promotes the survival of cardiomyocytes by activating type 1 IGF receptor (IGF-1R). Within the myocardium, IGF-1 action is modulated by IGF binding protein-3 (IGFBP-3), which sequesters IGF-1 away from IGF-1R.
Patrizia Fabbi +11 more
doaj +1 more source
Insulin-like growth factor-1 in articular cartilage repair for osteoarthritis treatment
Arthritis Research & Therapy, 2021 Articular cartilage repair is a critical issue in osteoarthritis (OA) treatment. The insulin-like growth factor (IGF) signaling pathway has been implicated in articular cartilage repair.
Caining Wen +5 more
semanticscholar +1 more source
The antagonistic pleiotropy of insulin‐like growth factor 1
Aging Cell, 2021 While insulin‐like growth factor‐1 (IGF‐1) is a well‐established modulator of aging and longevity in model organisms, its role in humans has been controversial.
William B Zhang +3 more
semanticscholar +1 more source