Results 11 to 20 of about 714,864 (392)
Insulin-like growth factor binding protein-3 (IGFBP-3) is a vital protein exist in circulation which interacts with high affinity to insulin-like growth factor (IGFs) altering their activities.
Elham Jafari+6 more
doaj +5 more sources
Insulin-like growth factor-1 in CNS and cerebrovascular aging [PDF]
Insulin-like growth factor-1 (IGF-1) is an important anabolic hormone that decreases with age. In the past two decades, extensive research has determined that the reduction in IGF-1 is an important component of the age-related decline in cognitive ...
Anna Csiszar+6 more
core +7 more sources
Insulin-like growth factor-1 deficiency and metabolic syndrome [PDF]
Consistent evidence associates IGF-1 deficiency and metabolic syndrome. In this review, we will focus on the metabolic effects of IGF-1, the concept of metabolic syndrome and its clinical manifestations (impaired lipid profile, insulin resistance ...
G. Aguirre+3 more
semanticscholar +4 more sources
The signaling landscape of insulin-like growth factor 1. [PDF]
The sheer amplitude of biological actions of insulin-like growth factor I (IGF-1) affecting all types of cells in all tissues suggests a vast signaling landscape for this ubiquitous humoral signal. While the canonical signaling pathways primarily involve the Ras/MAPK and PI3K/AKT cascades, the evolutionary conservation of insulin-like peptides (ILPs ...
Khan MZ, Zugaza JL, Torres Aleman I.
europepmc +3 more sources
Insulin-like growth factor-1 and zinc
Nejat Akar
doaj +2 more sources
Insulin-like growth factor 1 (IGF-1): a growth hormone [PDF]
To contribute to the debate about whether growth hormone (GH) and insulin-like growth factor 1 (IGF-1) act independently on the growth process.To describe growth in human and animal models of isolated IGF-1 deficiency (IGHD), such as in Laron syndrome (LS; primary IGF-1 deficiency and GH resistance) and IGF-1 gene or GH receptor gene knockout (KO) mice.
Z. Laron,
semanticscholar +4 more sources
Insulin-like Growth Factor 1 Signaling in Mammalian Hearing [PDF]
Insulin-like growth factor 1 (IGF-1) is a peptide hormone belonging to the insulin family of proteins. Almost all of the biological effects of IGF-1 are mediated through binding to its high-affinity tyrosine kinase receptor (IGF1R), a transmembrane receptor belonging to the insulin receptor family.
Silvia Murillo-Cuesta+8 more
openaire +5 more sources
Insulin-Like Growth Factor-1 as a Vascular Protective Factor [PDF]
Recent advances in cardiology have focused on proliferation and regeneration as potential cardiovascular defense mechanisms. Within this framework, growth factors are acquiring increasing importance; insulin-like growth factor-1 (IGF-1) emerges among them for its versatile pleiotropic actions.
E. Conti+6 more
openaire +4 more sources
Molecular Characterization and Expression Analysis of Insulin-like Growth Factor-1 and Insulin-like Growth Factor Binding Protein-1 Genes in Qinghai-Tibet Plateau and Lowland [PDF]
Insulin-like growth factor-1 (IGF-1) and insulin-like growth factor binding protein-1 (IGFBP-1) play a pivotal role in regulating cellular hypoxic response.
Ya-bing Chen+3 more
doaj +1 more source