Results 81 to 90 of about 499,115 (339)

Insulin-like growth factor binding protein-3 in preterm infants with retinopathy of prematurity

Indian Journal of Ophthalmology, 2012
Background: Retinopathy of prematurity (ROP) is the main cause of visual impairment in preterm newborn infants. Objective: This study was conducted to determine whether insulin-like growth factor binding protein -3 (IGFBP-3) is associated with ...
Manizheh Mostafa Gharehbaghi, Ali Peirovifar, Karim Sadeghi, Haleh Mostafidi   +3 more
doaj   +1 more source

ADAM 12, a Disintegrin Metalloprotease, Interacts with Insulin-like Growth Factor-binding Protein-3*

Journal of Biological Chemistry, 2000
Insulin-like growth factor-binding protein (IGFBP)-3 binds the insulin-like growth factors with high affinity and modulates their actions. Proteolytic cleavage of IGFBP-3 may regulate insulin-like growth factor bioavailability.
Zengdun Shi, Wenzhong Xu, F. Loechel, U. Wewer, L. Murphy   +4 more
semanticscholar   +1 more source

Disease Progression Mediated by Egr-1 Associated Signaling in Response to Oxidative Stress [PDF]

, 2012
When cellular reducing enzymes fail to shield the cell from increased amounts of reactive oxygen species (ROS), oxidative stress arises. The redox state is misbalanced, DNA and proteins are damaged and cellular transcription networks are activated.
Abdulkadir, Abdulkadir, Aggeli, Arsenian, Banks, Baron, Bedadala, Bedard, Bjelakovic, Bjelakovic, Bonventre, Brand, Calogero, Cao, Cao, Chang, Chen, Christy, Christy, Cramer, Datta, Dixit, Dixit, Dyson, Dyson, Eidelman, Elisabeth Deindl, Eto, Eto, Fahmy, Fahmy, Feldman, Forsberg, Förstermann, Gao, Gashler, Hallahan, Halliwell, Harja, Harman, Harrison, Hasan, Hasan, Hebert, Heo, Hill, Hirata, Huang, Irani, Iyoda, Izumi, Judith-Irina Pagel, Katsarou, Kawamura, Khachigian, Khachigian, Konishi, Lee, Liao, Lim, Lukac, Marais, Meira, Nishi, Nose, Nose, Nozik-Grayck, Ohba, Ouellette, Pagel, Paron, Pavletich, Peskin, Pines, Preston, Radisky, Sakamoto, Sattler, Schwachtgen, Sies, Sies, Stuart, Sudenga, Tell, Tell, Tell, Tell, Terashima, Treisman, Tsai-Morris, Vickers, Vivekananthan, Wang, Whitmarsh, Yan, Yan, Yang, Yang, Ye, Yu   +99 more
core   +2 more sources

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Single nucleotide polymorphism in Egyptian cattle insulin-like growth factor binding protein-3 gene

Journal of Genetic Engineering and Biotechnology, 2014
Insulin-like growth factor binding protein-3 (IGFBP-3) gene is a structural gene responsible for the multiple influences of insulin-like growth factors (IGFs) system. It is considered as a candidate gene for growth and production traits.
Othman E. Othman, Sally S. Alam, Sekena H. Abd El-Aziem   +2 more
doaj   +1 more source

Insulin-like-growth-factor-binding-protein-3 (IGFBP-3) contrasts melanoma progression in vitro and in vivo. [PDF]

PLoS ONE, 2014
Insulin-like-factor-binding-protein 3 (IGFBP-3) is known to modulate the activity of insulin-like growth factors (IGFs) besides having a number of IGF-independent effects on cell growth and survival. IGFBP-3 has been reported to decrease significantly in
Antimo Naspi, Vincenzo Panasiti, Franco Abbate, Vincenzo Roberti, Valeria Devirgiliis, Michela Curzio, Martina Borghi, Francesco Lozupone, Simone Carotti, Sergio Morini, Eugenio Gaudio, Stefano Calvieri, Paola Londei   +12 more
doaj   +1 more source

Short children born small for gestational age (SGA) : puberty, hormonal profiles, combined GnRHa and GH treatment and (epi)genetics of 2 IGFBP gene promotors [PDF]

, 2008
In the Netherlands, children who remain short after being born small for gestational age (SGA) are treated with growth hormone (GH). The clinical studies described in this thesis focused on treatment options in short children born SGA who came under ...
Kaay, D.C.M. (Danielle) van der
core  

Comprehensive profiling of zebrafish hepatic proximal promoter CpG island methylation and its modification during chemical carcinogenesis [PDF]

, 2011
Background\ud DNA methylation is an epigenetic mechanism associated with regulation of gene expression and it is modulated during chemical carcinogenesis.
Chipman, J Kevin, Gong, Zhiyuan, Mirbahai, Leda, Williams, Timothy D, Zhan, Huiqing   +4 more
core   +4 more sources

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

QUASI-EXPERIMENTAL EVALUATION OF ZINC SUPPLEMENTATION ON MEAN SERUM INSULIN LIKE GROWTH FACTOR-1 (IGF-1) AND INSULIN LIKE GROWTH FACTOR BINDING PROTEIN-3 (IGFBP-3) LEVELS IN PAKISTANI SHORT STATURED CHILDREN

Pakistan Armed Forces Medical Journal, 2020
Objective: To investigate the influence of supplemental zinc on the levels of insulin like growth factor-1 (IGF-1) and insulin like growth factor binding protein-3 (IGFBP-3) in short statured Pakistani children of 3-6 years of age. Study Design: Quasi-
Sadia Kirn, Amir Ijaz, Safia Fatima, Dilshad Ahmed Khan, Sarmad Nasir   +4 more
doaj