Results 71 to 80 of about 590,806 (400)

Insulin-like growth factor (IgF)-I, IgF binding protein-3, and prostate cancer: correlation with gleason score

International Brazilian Journal of Urology, 2015
Introduction Non-androgenic growth factors are involved in the growth regulation of prostate cancer (PCa). Objective This is the first Brazilian study to correlate, in a population of patients operated for PCa, PSA, total testosterone, insulin-like ...
Lívia L. Corrêa, Leonardo Vieira Neto, Giovanna A. Balarini Lima, Rafael Gabrich, Luiz Carlos D. de Miranda, Mônica R. Gadelha   +5 more
doaj   +1 more source

Differential effects of insulin-like growth factor binding proteins-1, -2, -3, and -6 on cultured growth plate chondrocytes [PDF]

, 2002
Differential effects of insulin-like growth factor binding proteins-1, -2, -3, and -6 on cultured growth plate chondrocytes.BackgroundIn children with chronic renal failure (CRF), impairment of longitudinal growth is in part due to excess amounts of ...
Durham, Susan K., Kiepe, Daniela, Mehls, Otto, Powell, David R., Tönshoff, Burkhard, Ulinski, Tim   +5 more
core   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Acromegaly with Normal Insulin-Like Growth Factor-1 Levels and Congestive Heart Failure as the First Clinical Manifestation [PDF]

Endocrinology and Metabolism, 2015
The leading cause of morbidity and mortality in patients with acromegaly is cardiovascular complications. Myocardial exposure to excessive growth hormone can cause ventricular hypertrophy, hypertension, arrhythmia, and diastolic dysfunction.
Hyae Min Lee, Sun Hee Lee, In-Ho Yang, In Kyoung Hwang, You Cheol Hwang, Kyu Jeung Ahn, Ho Yeon Chung, Hui-Jeong Hwang, In-Kyung Jeong   +8 more
doaj   +1 more source

Differential interactions between IGFBP-3 and transforming growth factor-beta (TGF-β) in normal vs cancerous breast epithelial cells [PDF]

In addition to modulating insulin-like growth factors action, it is now clear that insulin-like growth factor-binding protein-3 also has intrinsic effects on cell growth and survival.
AC Williams, AD Hollowood, AD Hollowood, AM Taylor, CA Fowler, CM Perks, CM Perks, CM Perks, CM Perks, CW Daniel, HD Soule, JI Jones, JL Martin, KL Schmeichel, KW Colston, LI Gold, M Reiss, MA Chrenek, ME Yateman, P Cohen, R Rajah, S Fanayan, S Kansra, SC Davies, SM Leal, Y Oh, Y Oh, Y Oh, Z Pietrzkowski, ZP Gill   +29 more
core   +2 more sources

The insulin-like growth factor I receptor regulates glucose transport by astrocytes [PDF]

, 2016
Previous findings indicate that reducing brain insulin-like growth factor I receptor (IGF-IR) activity promotes ample neuroprotection. We now examined a possible action of IGF-IR on brain glucose transport to explain its wide protective activity, as ...
Allaman, Barnes, Barros, Barros, Biondi, Booth, Boucher, Bunn, C, Carro, Chuquet, Cohen, Cohen, Dringen, Dull, Fernandez, Fernandez, Gazit, Gontier, Gonzalez, Hamai, Jakoby, Kenyon, Koshy, Kum, Kuntner, L, La Joie, Ligensa, Liu, Loaiza, Lopez-Otin, M, Magalhaes Filho, Masters, Mathiisen, Matsunaga, Mergenthaler, Morgello, Muhic, Munive, Nimmerjahn, Nishijima, Perez-Alvarez, Pfaffl, Porras, Roy, Vilchez, Wieman, Winkler   +49 more
core   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

Differential Expression of Insulin-Like Growth Factor-I Receptor on Human Bone Marrow-Derived Mesenchymal Stem Cells Induced by Tumor Necrosis Factor-?

International Journal of Organ Transplantation Medicine, 2014
Background: Cell-based therapy has been implicated in the treatment of liver diseases. Mesenchymal stem cells from various sources such as bone marrow are available. These cells are one of the major candidates in cell therapy.
Z Sahraean, M Ayatollahi, R Yaghobi, M Shariati   +3 more
doaj  

Insulin-Like Growth Factor (IGF)-I and Insulin in Normal and Growth-Restricted Mother/Infant Pairs

Mediators of Inflammation, 2007
Insulin-like growth factor (IGF)-I and insulin are essential for fetal growth. We investigated perinatal changes of both factors in 40 mothers and their 20 appropriate-for-gestational-age (AGA) and 20 intrauterine-growth-restricted (IUGR) fetuses and ...
Ariadne Malamitsi-Puchner, Despina D. Briana, Dimitrios Gourgiotis, Maria Boutsikou, Karl-Philipp Puchner, Stavroula Baka, Antonios Marmarinos, Dimitrios Hassiakos   +7 more
doaj   +1 more source

Myogenic Vector Expression of Insulin-like Growth Factor I Stimulates Muscle Cell Differentiation and Myofiber Hypertrophy in Transgenic Mice (*)

Journal of Biological Chemistry, 1995
The avian skeletal α-actin gene was used as a template for construction of a myogenic expression vector that was utilized to direct expression of a human IGF-I cDNA in cultured muscle cells and in striated muscle of transgenic mice. The proximal promoter
M. Coleman, F. DeMayo, K. Yin, Heung-Man Lee, R. Geske, Chuck Montgomery, R. Schwartz   +6 more
semanticscholar   +1 more source