Results 31 to 40 of about 470,139 (379)

Consequences of Postnatally Elevated Insulin-Like Growth Factor-II in Transgenic Mice: Endocrine Changes and Effects on Body and Organ Growth. [PDF]

, 1994
Insulin-like growth factor-II (IGF-II) is an important regulator of embryonic growth and differentiation, but its function in postnatal life is unclear. To address this point, we generated transgenic mice harboring fusion genes in which a human IGF-II
Blum, Werner F., Brem, Gottfried, Föll, Jürgen, Kramer, Rainer, Wolf, Eckhard   +4 more
core   +1 more source

Recurrent Severe Hypoglycemia Secondary to Benign Phyllodes Tumour of the Breast

Journal of the ASEAN Federation of Endocrine Societies, 2022
Non-Islet Cell Tumor-induced hypoglycemia (NICTH) secondary to phyllodes tumour is extremely rare but potentially life threatening if not treated promptly.
Hwee Ching Tee, Vijiya Mala Valayatham
doaj   +1 more source

IGF-II promotes neuroprotection and neuroplasticity recovery in a long-lasting model of oxidative damage induced by glucocorticoids

Redox Biology, 2017
Insulin-like growth factor-II (IGF-II) is a naturally occurring hormone that exerts neurotrophic and neuroprotective properties in a wide range of neurodegenerative diseases and ageing.
E. Martín-Montañez, C. Millon, F. Boraldi, F. Garcia-Guirado, C. Pedraza, E. Lara, L.J. Santin, J. Pavia, M. Garcia-Fernandez   +8 more
doaj   +1 more source

Estudio inmunocitoquímico y molecular de cultivo primario de tejido molar

Biomédica: revista del Instituto Nacional de Salud, 2006
Introducción. La enfermedad trofoblástica gestacional comprende un conjunto de patologías caracterizadas por crecimiento e invasión anómalos del trofoblasto.
Yinth Andrea Bernal, Luis Eduardo Díaz, Jinneth Acosta, Cecilia Crane, Stella Carrasco-Rodríguez, Antonio José Bermúdez, Myriam Sánchez-Gómez   +6 more
doaj   +1 more source

Circulating Insulin-Like Growth Factor II and Colorectal Adenomas* [PDF]

The Journal of Clinical Endocrinology & Metabolism, 2000
Abstract Circulating insulin-like growth factor I (IGF-I) and IGF-binding protein-3 (IGFBP-3) may be risk factors for the development of colorectal cancer. On the other hand, IGF-II and IGFBP-2 are overexpressed in colorectal carcinomas.
Renehan, Andrew G., Painter, John E., O'Halloran, Domhnall, Atkin, Wendy S., Potten, Christopher S., O'Dwyer, Sarah T., Shalet, Stephen M.   +6 more
openaire   +4 more sources

Niveles séricos de los factores de crecimiento similares a la insulina I y II y su proteína 3 de enlace en mujeres con lesiones escamosas intraepiteliales y cáncer de cuello uterino

Biomédica: revista del Instituto Nacional de Salud, 2006
Introducción. La citología cervico-uterina como prueba de tamizaje del cáncer cervical tiene limitaciones. Un marcador que permita identificar mujeres en riesgo de desarrollar este cáncer sería de utilidad para prevenir el desarrollo de esta enfermedad ...
Martha Lucía Serrano, Alfredo Romero, Ricardo Cendales, Myriam Sánchez Gómez, María Mercedes Bravo   +4 more
doaj   +1 more source

Paraneoplastic Hypoglycaemia: A Rare Manifestation of Pelvic Gastrointestinal Stromal Tumour [PDF]

Journal of Clinical and Diagnostic Research, 2017
Non-Islet Cell Tumour Induced Hypoglycaemia (NICTH), presenting with recurrent fasting hypoglycaemia is a very rare paraneoplastic syndrome. It usually presents with large metastatic mesenchymal tumours.
Ashish Singhal, Rahat Hadi, Kiranpreet Mehrotra, Shivani Rastogi, Shakeel Masood   +4 more
doaj   +1 more source

Heterogeneity for IGF-II production maintained by public goods dynamics in neuroendocrine pancreatic cancer [PDF]

, 2015
The extensive intratumor heterogeneity revealed by sequencing cancer genomes is an essential determinant of tumor progression, diagnosis, and treatment.
Daniela A. Ferraro, Dexter, Gerhard Christofori, Jourdan, Karey, Lamm, Marco Archetti   +6 more
core   +1 more source

Apoptosis in the Pancreatic Islet Cells of the Neonatal Rat Is Associated with a Reduced Expression of Insulin-Like Growth Factor II that May Act as a Survival Factor*

Endocrinology, 1998
Jim Petrik, Edith Arany, Timothy J. McDonald, David J. Hill   +3 more
semanticscholar   +3 more sources

Insulin and IGF-1 improve mitochondrial function in a PI-3K/Akt-dependent manner and reduce mitochondrial generation of reactive oxygen species in Huntington’s disease knock-in striatal cells [PDF]

, 2014
Akt, protein kinase B; ARE, antioxidant response element; Erk, extracellular signal-regulated kinase; CBP, CREB-binding protein; CREB, cAMP response-element (CRE) binding protein; CDK, cyclin-dependent kinase; DHE, dihydroethidium; Drp1, dynamin-related ...
Oliveira, Ana M., Oliveira, Catarina R., Rego, A. Cristina, Ribeiro, Márcio, Rosenstock, Tatiana R.   +4 more
core   +1 more source