Understanding the mechanism of insulin and insulin-like growth factor (IGF) receptor activation by IGF-II. [PDF]
PLoS ONE, 2011 BACKGROUND: Insulin-like growth factor-II (IGF-II) promotes cell proliferation and survival and plays an important role in normal fetal development and placental function.
Clair L Alvino +6 more
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Recurrent Severe Hypoglycemia Secondary to Benign Phyllodes Tumour of the Breast
Journal of the ASEAN Federation of Endocrine Societies, 2022 Non-Islet Cell Tumor-induced hypoglycemia (NICTH) secondary to phyllodes tumour is extremely rare but potentially life threatening if not treated promptly.
Hwee Ching Tee, Vijiya Mala Valayatham
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The receptor for insulin-like growth factor II mediates an insulin-like response. [PDF]
The EMBO Journal, 1987 Insulin-like growth factor II (IGF-II) shares sequence homology and predicted three-dimensional structure with insulin and IGF-I. IGF-II can bind, therefore, to a limited extent with the receptors for these two other hormones, as well as to a distinct receptor for IGF-II.
Joji Hari +5 more
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Redox Biology, 2017 Insulin-like growth factor-II (IGF-II) is a naturally occurring hormone that exerts neurotrophic and neuroprotective properties in a wide range of neurodegenerative diseases and ageing.
E. Martín-Montañez +8 more
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Circulating Insulin-Like Growth Factor II and Colorectal Adenomas* [PDF]
The Journal of Clinical Endocrinology & Metabolism, 2000 Abstract Circulating insulin-like growth factor I (IGF-I) and IGF-binding protein-3 (IGFBP-3) may be risk factors for the development of colorectal cancer. On the other hand, IGF-II and IGFBP-2 are overexpressed in colorectal carcinomas.
Renehan, Andrew G. +6 more
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Insulin and insulin like growth factor II endocytosis and signaling via insulin receptor B [PDF]
, 2013 Insulin and insulin-like growth factors (IGFs) act on tetrameric tyrosine kinase receptors controlling essential functions including growth, metabolism, reproduction and longevity.
Barcos, Lucía Soledad +6 more
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Estudio inmunocitoquímico y molecular de cultivo primario de tejido molar
Biomédica: revista del Instituto Nacional de Salud, 2006 Introducción. La enfermedad trofoblástica gestacional comprende un conjunto de patologías caracterizadas por crecimiento e invasión anómalos del trofoblasto.
Yinth Andrea Bernal +6 more
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Identification and characterization of insulin-like growth factor receptors on adult rat cardiac myocytes: linkage to inositol 1,4,5-trisphosphate formation. [PDF]
, 1992 Cultured cardiac myocytes from adult Sprague-Dawley rats express both insulin-like growth factor-I (IGF-I) receptors and insulin-like growth factor-II/mannose 6-phosphate (IGF-II/Man6P) receptors and respond to IGF-I with a dose-dependent accumulation of
Berg, Ingeborg +5 more
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Biomédica: revista del Instituto Nacional de Salud, 2006 Introducción. La citología cervico-uterina como prueba de tamizaje del cáncer cervical tiene limitaciones. Un marcador que permita identificar mujeres en riesgo de desarrollar este cáncer sería de utilidad para prevenir el desarrollo de esta enfermedad ...
Martha Lucía Serrano +4 more
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Insulin and IGF-1 improve mitochondrial function in a PI-3K/Akt-dependent manner and reduce mitochondrial generation of reactive oxygen species in Huntington’s disease knock-in striatal cells [PDF]
, 2014 Akt, protein kinase B; ARE, antioxidant response element; Erk, extracellular signal-regulated kinase; CBP, CREB-binding protein; CREB, cAMP response-element (CRE) binding protein; CDK, cyclin-dependent kinase; DHE, dihydroethidium; Drp1, dynamin-related ...
Oliveira, Ana M. +4 more
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