Profiling Of Volatiles In Tissues Of Salacia Reticulata Wight. With Anti-Diabetic Potential Using GC-MS And Molecular Docking [PDF]
arXiv, 2023 Type 2 diabetes mellitus is a global pandemic, it is a chronic, progressive and an incompletely understood metabolic condition. The disease is characterized by higher levels of sugar in blood caused either due to insufficient production of insulin or because of insulin resistance.
arxiv
Inflammation and insulin resistance [PDF]
Journal of Clinical Investigation, 2006 Over a hundred years ago, high doses of salicylates were shown to lower glucose levels in diabetic patients. This should have been an important clue to link inflammation to the pathogenesis of type 2 diabetes (T2D), but the antihyperglycemic and antiinflammatory effects of salicylates were not connected to the pathogenesis of insulin resistance until ...
Allison B. Goldfine +2 more
openaire +4 more sources
BMC Women's Health, 2023 Objective In this study, patients were divided into two groups. Patients with polycystic ovary syndrome (PCOS) and patients with polycystic ovary syndrome + Hashimoto's Thyroid (PCOS + HT).
Gülcan Gencer +2 more
doaj +1 more source
Pasireotide Long-Acting Release Treatment for Diabetic Cats with Underlying Hypersomatotropism [PDF]
, 2017 BACKGROUND: Long‐term medical management of hypersomatotropism (HS) in cats has proved unrewarding. Pasireotide, a novel somatostatin analogue, decreases serum insulin‐like growth factor 1 (IGF‐1) and improves insulin sensitivity in cats with HS when ...
Abraham +43 more
core +2 more sources
Security, extensibility, and redundancy in the Metabolic Operating System [PDF]
arXiv, 2023 People living with Type 1 Diabetes (T1D) lose the ability to produce insulin naturally. To compensate, they inject synthetic insulin. One common way to inject insulin is through automated insulin delivery systems, which use sensors to monitor their metabolic state and an insulin pump device to adjust insulin to adapt.
arxiv
Insulin Signaling and Insulin Resistance [PDF]
Journal of Investigative Medicine, 2013 Insulin resistance or its sequelae may be the common etiology of maladies associated with metabolic syndrome (eg, hypertension, type 2 diabetes, atherosclerosis, heart attack, stroke, and kidney failure). It is thus important to understand those factors that affect insulin sensitivity.
openaire +3 more sources
Betatrophin and Insulin Resistance
Metabolites, 2022 Betatrophin (angiopoietin-like protein 8 (ANGPTL8)) is a hormone that was recently discovered in the human liver. Multiple homologous sequences have been detected in mammalian liver, white adipose, and brown adipose tissues. Betatrophin is crucial for the development of type 2 diabetes (T2D), insulin resistance, and lipid metabolism.
Qi Guo, Shicheng Cao, Xiaohong Wang
openaire +3 more sources
Metabolic syndrome and insulin resistance in obese adolescents
Revista Paulista de Pediatria, 2014 Objective: To verify the prevalence of metabolic syndrome and insulin resistance in obese adolescents and its relationship with different body composition indicators.
Amanda Oliva Gobato +4 more
doaj +1 more source
Changing Clinical Characteristics according to Insulin Resistance and Insulin Secretion in Newly Diagnosed Type 2 Diabetic Patients in Korea [PDF]
Diabetes & Metabolism Journal, 2015 BackgroundThe role of increased insulin resistance in the pathogenesis of type 2 diabetes has been emphasized in Asian populations. Thus, we evaluated the proportion of insulin resistance and the insulin secretory capacity in patients with early phase ...
Jang Won Son +5 more
doaj +1 more source
Serum IgG2 levels are specifically associated with whole-body insulin-mediated glucose disposal in non-diabetic offspring of type 2 diabetic individuals. a cross-sectional study [PDF]
, 2018 .Preclinical studies suggested that IgG2c isotype may specifically impair skeletal muscle insulin sensitivity in mice. In this study we investigated the association between serum levels of the four IgG subclasses and insulin sensitivity in non-diabetic
Andreozzi, F +11 more
core +2 more sources