Results 41 to 50 of about 4,110,467 (359)

Insulin resistance in children [PDF]

open access: yesCurrent Opinion in Pediatrics, 2019
Purpose of review Insulin resistance (IR) is a clinical condition due to the decline in the efficiency of insulin promoting glucose uptake and utilization. The aim of this review is to provide an overview of the current knowledge on IR in children, focusing on its physiopathology, the most appropriate methods of measurement of ...
Tagi V. M., Giannini C., Chiarelli F.
openaire   +5 more sources

Analysis of factors associated with insulin resistance in young women: A cross-sectional study

open access: yesClinical Nutrition Open Science, 2023
Summary: Background & aims: Impaired glucose tolerance in young women may lead to the future development of gestational diabetes mellitus and/or type 2 diabetes mellitus.
Isaki Hanamura   +6 more
doaj   +1 more source

Metabolic Inflammation and Insulin Resistance in Obesity

open access: yesCirculation Research, 2020
Supplemental Digital Content is available in the text. Obesity is becoming an epidemic in the United States and worldwide and increases risk for many diseases, particularly insulin resistance, type 2 diabetes mellitus, and cardiovascular disease.
Huaizhu Wu, C. Ballantyne
semanticscholar   +1 more source

Obesity, Insulin Resistance, and Type 2 Diabetes: Associations and Therapeutic Implications

open access: yesDiabetes, Metabolic Syndrome and Obesity : Targets and Therapy, 2020
Obesity is a triggering factor for diabetes associated with insulin resistance. In individuals who are obese, higher amounts of non-esterified fatty acids, glycerol, hormones, and pro-inflammatory cytokines that could participate in the development of ...
Yohannes Tsegyie Wondmkun
semanticscholar   +1 more source

Insulin Signaling and Insulin Resistance [PDF]

open access: yesJournal of Investigative Medicine, 2013
Insulin resistance or its sequelae may be the common etiology of maladies associated with metabolic syndrome (eg, hypertension, type 2 diabetes, atherosclerosis, heart attack, stroke, and kidney failure). It is thus important to understand those factors that affect insulin sensitivity.
openaire   +2 more sources

Role of Skeletal Muscle in Insulin Resistance and Glucose Uptake.

open access: yesComprehensive Physiology, 2020
The skeletal muscle is the largest organ in the body, by mass. It is also the regulator of glucose homeostasis, responsible for 80% of postprandial glucose uptake from the circulation.
Karla E. Merz, D. Thurmond
semanticscholar   +1 more source

Obesity, Bioactive Lipids, and Adipose Tissue Inflammation in Insulin Resistance

open access: yesNutrients, 2020
Obesity is a major risk factor for the development of insulin resistance and type 2 diabetes. The exact mechanism by which adipose tissue induces insulin resistance is still unclear.
Iwona Kojta   +2 more
semanticscholar   +1 more source

Insulin Resistance Concepts [PDF]

open access: yesDiabetes Care, 2007
Perspectives on the News commentaries are now part of a new, free monthly CME activity. The Mount Sinai School of Medicine, New York, New York, is designating this activity for 2.0 AMA PRA Category 1 credits. If you wish to participate, review this article and visit www.diabetes.procampus.net to complete a posttest and receive a certificate.
openaire   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

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