Results 61 to 70 of about 167,996,906 (262)
The Role of Spastin in Axon Biology
Frontiers in Cell and Developmental Biology, 2022 Neurons are highly polarized cells with elaborate shapes that allow them to perform their function. In neurons, microtubule organization—length, density, and dynamics—are essential for the establishment of polarity, growth, and transport. A mounting body Ana Catarina Costa, Ana Catarina Costa, Monica Mendes Sousa +2 moredoaj +1 more sourcePartial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig +10 morewiley +1 more sourceIntegrative annotation of 21,037 human genes validated by full-length cDNA clones [PDF]
, 2004 The human genome sequence defines our inherent biological potential; the realization of the biology encoded therein requires knowledge of the function of each gene. Currently, our knowledge in this area is still limited.Terwilliger Joseph D, Nagata, Naoki, Kuryshev, Vladimir, Eveno, E., Imbeaud, S., Makalowski, W., Yoshiyuki Suzuki, Sakai, Katsunaga, Graudens Esther, de Souza, S.J., Sakamoto Shigetaka, Thomas, M.A., Ashurst, Jennifer, Kanehisa Minoru, Shinsei Minoshima, Korn, B., Mitsuteru Nakao, Robert L Strausberg, Unneberg, P., Eveno Eric, Ren, S. -X, Lenhard, B., Shiba, Rie, Hilton Phillip, Sakate, Ryuichi, Bromberg Susan K, Gopal R. Gopinath, Nakai, K., Jia, Libin, Alexander Kanapin, Momoki Hirai, Barrero, R., Strausberg Robert L, Steward Charles, Suzuki, Yutaka, Okazaki, Yasushi, Makalowski Wojciech, Okido Toshihisa, Fukami-Kobayashi Kaoru, Satoshi Oota, Motohiko Tanino, Hide, Winston, R. Gopinath, Gopal, Auffray, C., de Souza, S., Shimoyama, Mary, Dubchak Inna, Osamu Ogasawara, Erimi Harada, Quackenbush, John, Jun-ichi Takeda, Steward, C., Kikuno, Reiko, Hirai, M., Isogai, T., Piero Carninci, Matsuda, Hideo, Ryuichi Sakate, Suzuki Yutaka, Kenta Nakai, Chen Zhu, Hiroaki Sakai, Shiba, R., Okubo, K., Nomura Nobuo, Sandro J. de Souza, Taylor Todd, Toshihisa Takagi, Thierry-Mieg Jean, Fukuchi Satoshi, Nagasaki, H., Hayashizaki, Yoshihide, Bellgard Matthew, Chelala Claude, Terwilliger, J., Bruford Elspeth, Apweiler Rolf, Christine Couillault, Takeya Kasukawa, Suzuki Mami, Nobuo Nomura, Sakai Katsunaga, Korn, Bernhard, Mulder, N., Amid, Clara, Schupp, Ingo, Kasukawa Takeya, Veeramachaneni, V., Wagner, L., Yura Kei, Annemarie Poustka, Yura, Kei, Ian Hopkinson, Hashimoto, Katsuyuki, Bono, H., Endo, T., Couillault, Christine, Elspeth Bruford, Bono Hidemasa, Ota Toshio, Reiko Kikuno, O'Donovan, C., Ota, M., Jia, L., Han Michael, Okazaki, Y., Shuang-Xi Ren, Tamura, T., Sakamoto, S., Bromberg, Susan K., Ohara, Osamu, Korn Bernhard, Hyang-Yoo, S., Nagata, N., Karavidopoulou Youla, Koyanagi, K.O., Soares, Bento, Tanaka, H., Charles Steward, Yamasaki, Chisato, Saitou Naruya, Yoo, H-S, Norikazu Yasuda, Imbeaud, Sandrine, Roberto A Barrero, Nishikawa Tetsuo, Izabela Makalowska, Jin Lihua, Nigam, Rajni, Gopinath, G. R., Motonori Ota, Stephen Sherry, Hiroshi Tanaka, Yayoi Kaneko, Jean Thierry-Mieg, Okada, Norihiro, Kelso, J. ; https://orcid.org/, Fukami-Kobayashi, K., Otsuki, Tetsuji, Yura, K., Ikeo, K., Hanaoka, Hideki, Rajni Nigam, Tanino, Motohiko, Sugano Sumio, Matthew Bellgard, Kaoru Fukami-Kobayashi, Oota Satoshi, Shimizu, Nobuyoshi, Sugano, Sumio, Satoshi Fukuchi, O'Donovan, Claire, Ren, S-X, Todd Taylor, Kimura Kouichi, Bonaldo, Maria de Fatima, Poustka, Annemarie, Koyanagi, K., Shimizu, N., Kanapin Alexander, Bono, Hidemasa, Chelala, Claude, Koyanagi, Kanako O., Devignes, M. -D, Stodolsky, M., Brookes, A., Strausberg, R., Danielle Thierry-Mieg, Stefan Wiemann, Eyras, Eduardo, Brookes, Anthony J., Mami Suzuki, Lukas Wagner, Hilton, Phillip, Barrero Roberto A, Suzuki Yoshiyuki, Sugawara Hideaki, Kasukawa, T., Yoshihide Hayashizaki, Mano, Shuhei, Craig Gough, Takashi Makino, Takahashi, Aiko, Shuhei Mano, Takashi Gojobori, Suzuki, Yoshiyuki, Libin Jia, Kousaku Okubo, Han, Michael, Koyanagi Kanako O, Hidemasa Bono, Inoko, Hidetoshi, Hinz Ursula, Auffray Charles, Strausberg, R.L., Yamaguchi-Kabata, Y., Devignes, Marie Dominique, Norihiro Okada, Hideki Hanaoka, Oota, S., Fujii Yasuyuki, Han, Ze-Guang, Isogai Takao, Kasprzyk, A., Ranajit Chakraborty, Itoh, Takeshi, Terwilliger, Joseph D., Florence Servant, Mulder, Nicola, Takahashi, A., Piatier-Tonneau, Dominique, Hirakawa Mika, R. Gopinath, G., Bromberg, S., Hinz, Ursula, Suwa Makiko, Hopkinson, I., Thierry-Mieg Danielle, Chelala, C., Mewes, Hans Werner, Amid, C., Hirakawa, Mika, Servant, Florence, Hishiki, T., Nomura, N., Steward, Charles, Tamiya, G., Rie Shiba, Hahn Yoonsoo, Fujii, Y., Tateno Yoshio, Sugawara, H., Ren, Shuang Xi, Naoki Nagata, Soares Bento, Hidetoshi Inoko, Sakai, H., Schupp, I., Sakamoto, Shigetaka, Lenhard Boris, Yasuda Norikazu, Nakai Kenta, Kim, S., Kersey Paul, Watanabe Shinya, de Bonaldo, M., Hishiki, Teruyoshi, Mariage-Samson, R., Toshinori Endo, Hishiki Teruyoshi, Bellgard, Matthew, Mano, S., Nishikawa, Tetsuo, Okido, T., Wiemann, S., Anne Estreicher, Hayashizaki, Y., Miyazaki, Satoru, Susan K Bromberg, Apweiler, R., Katsunaga Sakai, Han, M., Oishi Michio, Hide, W., Kanako O Koyanagi, Tetsuo Nishikawa, Nobuyoshi Shimizu, Carninci, Piero, Makino Takashi, Dubchak, Inna, Yoo, Hyang-Sook, Ren, S., Strausberg, R. L., Estreicher, A., Yamasaki Chisato, Eyras, E., Tanaka Hiroshi, Nagai, Keiichi, Wilming, Laurens, Phillip Hilton, Ota, T., Go, M., Wilming Laurens, Winston Hide, Hopkinson Ian, Yasuda, Norikazu, Graudens, Esther, Regine Mariage-Samson, Harada, Erimi, Suwa, Makiko, Claude Chelala, Sherry Stephen, Yamaguchi-Kabata, Yumi, Eduardo Eyras, Han, Z. -G, Chakraborty, Ranajit, Teruyoshi Hishiki, Yoo, H-S., Mariage-Samson, Regine, Piatier-Tonneau Dominique, Kim, Sangsoo, Takeda, Jun Ichi, Bento Soares, Poustka, A., Zhu Chen, Makalowska, Izabela, Okada, N., Youla Karavidopoulou, Amid Clara, Suzuki, M., Sakai, K., Unneberg, Per, Wiemann Stefan, Inna Dubchak, Taylor, T., Okido, Toshihisa, Charles Auffray, Kelso, J., Hirai Momoki, Jennifer Ashurst, Yasuyuki Fujii, Nigam, R., Nishikawa, Ken, Terwilliger, J.D., Gopal R Gopinath, Tetsuji Otsuki, Nakao Mitsuteru, Brookes Anthony J, Hahn, Y., Simpson, A.J., Debily, Marie-Anne, Sangsoo Kim, Imanishi Tadashi, Homma, Keiichi, Kasukawa, Takeya, Makalowska Izabela, Takeda, J-I, Yutaka Suzuki, Jin, Lihua, Terwilliger, J. D., Aiko Takahashi, Hyang-Yoo, Sook, Sakai Hiroaki, Shimizu Nobuyoshi, Michael A Thomas, Tadashi Imanishi, Esther Graudens, Paul Kersey, Stodolsky Marvin, Toshio Ota, Ren, Shuang-Xi, Carninci Piero, Tanaka, S., Imanishi, T., Yoshio Tateno, Simpson Andrew J, de Fatima Bonaldo, Maria, Yoo Hyang-Sook, Imbeaud Sandrine, Brookes, A.J., Kikuno Reiko, Tanaka, Susumu, Tamiya, Gen, de Souza Sandro J., Sugano, S., Tomohiro Yasuda, Wilming, L., Keiichi Nagai, Devignes, Marie-Dominique, Matsuda Hideo, Takeda, J. -I, Nishikawa, T., Thierry-Mieg, J., Hideki Nagasaki, Estreicher Anne, Harada, E., Ota, Toshio, Yumi Yamaguchi-Kabata, Kelso, Janet, Minoshima Shinsei, Tanaka, Hiroshi, Kimura, K., Ingo Schupp, Sumio Sugano, Piatier-Tonneau, D., Yasuda, T., Simpson, A. J., Minoru Kanehisa, Ren Shuang-Xi, Janet Kelso, Barrero, R.A., Eyras Jiménez, Eduardo, Kaneko Yayoi, Servant, F., Hideaki Sugawara, Tamura Takuro, Susumu Tanaka, Tonellato, Peter, Gopinath, Gopal R., Thomas Michael A, Poustka Annemarie, Sugawara, Hideaki, Sakai, Hiroaki, Nagata Naoki, Dominique Piatier-Tonneau, Gojobori Takashi, Oishi, M., Nagai Keiichi, Chisato Yamasaki, Koyanagi, K. O., Thomas, M. A., Ohtsubo, Masafumi, Shigetaka Sakamoto, Hanada Kousuke, Fukuchi, S., Andrew J Simpson, Chakraborty Ranajit, Sakate, R., Mewes Hans-Werner, Matsuda, H., Kaneko, Yayoi, Kasprzyk Arek, Hashimoto, K., Otsuki, T., Ursula Hinz, Keiichi Homma, Bellgard, M., Harada Erimi, Tanino Motohiko, Minoshima, Shinsei, R. Gopinath Gopal, Joseph D Terwilliger, Souza, Sandro J. de, Gopinath, G., Oota, Satoshi, Debily Marie-Anne, Kanapin, Alexander, Karavidopoulou, Y., De Fatima Bonaldo, M., Isogai, Takao, Per Unneberg, Okazaki Yasushi, Takeshi Itoh, Fukami-Kobayashi, Kaoru, Yoonsoo Hahn, Peter Tonellato, Hirakawa, M., Jin, L., Makino, Takashi, Thierry-Mieg, D., Brookes, A. J., Ohara Osamu, Gopinath, G.R., Takahashi Aiko, Bernhard Korn, Watanabe, S., Kazuho Ikeo, Takao Isogai, Okubo Kousaku, Unneberg, Per,, Souza, S., Yoshiyuki Sakaki, Ashurst, J., Michael Han, Kanehisa, Minoru, Gojobori, T., Barrero, R. A., de Souza, S. J., Sandrine Imbeaud, Bruford, Elspeth, Bromberg, S. K., Shimoyama, M., Makalowska, I., Simpson, A., Laurens Wilming, Devignes, M., Karavidopoulou, Youla, Han, Z-G., Otsuki Tetsuji, Hopkinson, Ian, Itoh Takeshi, Claire O'Donovan, Ogasawara, Osamu, Nakai, Kenta, Jia Libin, Okubo, Kousaku, Eveno, Eric, Shimoyama Mary, Unneberg Per, Hyang-Sook Yoo, Estreicher, Anne, Veeramachaneni, Vamsi, Servant Florence, Hans-Werner Mewes, Sakaki, Yoshiyuki, Quackenbush John, Sherry, S., Masafumi Ohtsubo, Veeramachaneni Vamsi, Kikuno, R., Wagner Lukas, Mika Hirakawa, Schupp Ingo, Vamsi Veeramachaneni, Ikeo Kazuho, Apweiler, Rolf, Kasprzyk, Arek, Sherry, Stephen, Takeda, J., Thierry-Mieg, Jean, Devignes Marie-Dominique, Eric Eveno, Nagai, K., Marie-Anne Debily, Yasuda, N., Mashima Jun, Carninci, P., Naruya Saitou, Shinya Watanabe, Mashima, J., Nakao, M., Satoru Miyazaki, Ohtsubo, M., Saitou, N., O'Donovan Claire, John Quackenbush, Kuryshev Vladimir, Miyazaki Satoru, Nishikawa, K., Nigam Rajni, Takagi, T., Han, Z., Kuryshev, V., Couillault, C., Yamaguchi-Kabata Yumi, Tamura, Takuro, Simpson, Andrew J., Watanabe, Shinya, Tanino, M., Tateno, Y., Hanaoka Hideki, Takagi, Toshihisa, Soares, B., Mulder Nicola, Mewes, H. -W, Bonaldo Maria de Fatima, Suzuki, Mami, Ikeo, Kazuho, Oishi, Michio, Mitiko Go, Lenhard, Boris, Okada Norihiro, Go, Mitiko, Homma Keiichi, Ota Motonori, Quackenbush, J., Nicola Mulder, Bromberg, S.K., Takeda Jun-ichi, Kersey, P., Rolf Apweiler, Suzuki, Y., Boris Lenhard, Vladimir Kuryshev, Hinz, U., Kanapin, A., Kei Yura, Saitou, Naruya, Chakraborty, R., Debily, Marie Anne, Ogasawara Osamu, Wagner, Lukas, Mewes, Hans-Werner, Taylor, Todd, Hanaoka, H., Gen Tamiya, Thomas, M., Miyazaki, S., Takuro Tamura, Kaneko, Y., Yasuda Tomohiro, Minoshima, S., Sakaki Yoshiyuki, Tanaka Susumu, Mano Shuhei, Yoo, H., Suwa, M., Ze-Guang Han, Tamiya Gen, Kouichi Kimura, Hashimoto Katsuyuki, Barrero, Roberto A., Sakaki, Y., Dubchak, I., Chen, Z., Debily, M., Fukuchi, Satoshi, Toshihisa Okido, Gough Craig, Fujii, Yasuyuki, Nishikawa Ken, Makiko Suwa, Nomura, Nobuo, Kersey, Paul, Auffray, Charles, Clara Amid, Sandro J de Souza, Gough, Craig, Shiba Rie, Tonellato, P., Mashima, Jun, Osamu Ohara, Wiemann, Stefan, Graudens, E., Ohara, O., Hanada, Kousuke, Endo Toshinori, Ohtsubo Masafumi, Sakate Ryuichi, Wojciech Makalowski, Homma, K., Hahn, Yoonsoo, Bruford, E., Gough, C., Go Mitiko, Yasuda, Tomohiro, Hirai, Momoki, Chen, Zhu, Nagasaki Hideki, Yasushi Okazaki, Imanishi, Tadashi, Nakao, Mitsuteru, Kimura, Kouichi, Nagasaki, Hideki, Mewes, H., Strausberg, Robert L., Hide Winston, Debily, M. -A, Stodolsky, Marvin, Kousuke Hanada, Thierry-Mieg, Danielle, Mewes, H-W, de Souza, Sandro J., Lihua Jin, Thomas, Michael A., Mary Shimoyama, Katsuyuki Hashimoto, Kim Sangsoo, Hayashizaki Yoshihide, Hilton, P., Anthony J Brookes, Mariage-Samson Regine, Jun Mashima, Ken Nishikawa, Takeda, Jun-ichi, Ashurst Jennifer, Yamasaki, C., Inoko, H., Makino, T., Arek Kasprzyk, Gojobori, Takashi, Makalowski, Wojciech, Hanada, K., Kanehisa, M., Couillault Christine, Michio Oishi, Eyras Eduardo, Marie-Dominique Devignes, Tateno, Yoshio, Tonellato Peter, Takagi Toshihisa, Marvin Stodolsky, Endo, Toshinori, Itoh, T., Bonaldo, M., Maria de Fatima Bonaldo, Han, Ze Guang, Ota, Motonori, Han Ze-Guang, Hideo Matsuda, Inoko Hidetoshi, Ogasawara, O., Kelso Janet, T Imanishi, T Gojobori, S Sugano, T Itoh, Hyang Sook Yoo, Sang Soo Kim +688 morecore +1 more sourceCombined endurance and resistance exercise training alters the spatial transcriptome of skeletal muscle in young adults
iScienceSummary: Chronic exercise training substantially improves skeletal muscle function and performance. The repeated demands and stressors of each exercise bout drive coordinated molecular adaptations within multiple cell types, leading to enhanced ...Michael J. Stec, Zachary A. Graham, Qi Su, Christina Adler, Min Ni, Valerie Le Rouzic, David R. Golann, Patrick J. Ferrara, Gabor Halasz, Mark W. Sleeman, Kaleen M. Lavin, Timothy J. Broderick, Marcas M. Bamman +12 moredoaj +1 more sourceInterferon gamma induced-ACSL5 shapes the lipidome of kidney tubular cells
iScienceSummary: Acyl-CoA synthetase long-chain family (ACSL) enzymes are critical in the activation of long-chain fatty acid. To determine the regulatory mechanisms of ACSL5 and its biological functions within the kidney tubule, we generated transcriptomic ...Virginie Poindessous, Julio L. Sampaio, Lydia Bouidghaghen, Ivan Nemazanyy, Alexandre Pallet, Maarten Naesens, Thibaut Vaulet, Dany Anglicheau, Nicolas Pallet +8 moredoaj +1 more sourceImpact of enteric neuronal loss on intestinal cell composition
iScienceSummary: Hirschsprung disease (HSCR) is a congenital disorder characterized by the absence of an enteric nervous system (ENS) in the distal gut. While the ENS is critical for normal gut function, its broader role in maintaining intestinal homeostasis ...Naomi J.M. Kakiailatu, Wei Zhang, Laura E. Kuil, Jonathan D. Windster, Eric Bindels, Joke T.M. Zink, Michael Vermeulen, Bianca M. de Graaf, Deepavali Sahadew, Thierry P.P. van den Bosch, Demi Huijgen, Cornelius E.J. Sloots, Rene M.H. Wijnen, Robert M.W. Hofstra, Emma de Pater, Veerle Melotte, Maria M. Alves +16 moredoaj +1 more source
