Results 71 to 80 of about 145,713 (206)

BMP2/BMPR1A is linked to tumour progression in dedifferentiated liposarcomas [PDF]

, 2016
Bone Morphogenic Protein 2 (BMP2) is a multipurpose cytokine, important in the development of bone and cartilage, and with a role in tumour initiation and progression.
Cassidy, A.P., Cassidy, J.W., Harris, O.B., O’Neill, H.L.   +3 more
core   +3 more sources

DNA-damage-associated protein co-expression network in cardiomyocytes informs on tolerance to genetic variation and disease

iScience
Summary: Cardiovascular disease (CVD) is associated with genetic variants and environmental factors. A consequence of multiple risk factors is DNA damage.
Omar Darrel Johnson, Sayan Paul, José Angel Gutiérrez, William Kent Russell, Michelle Claire Ward   +4 more
doaj   +1 more source

Functional Heterogeneity of Mouse Prostate Stromal Cells Revealed by Single-Cell RNA-Seq

iScience, 2019
Summary: We perform a single-cell RNA sequencing analysis to investigate the phenotypic and functional heterogeneity of the adult mouse prostate stromal cells.
Oh-Joon Kwon, Yiqun Zhang, Yumei Li, Xing Wei, Li Zhang, Rui Chen, Chad J. Creighton, Li Xin   +7 more
doaj   +1 more source

How neurons maintain their axons long-term: an integrated view of axon biology and pathology

Frontiers in Neuroscience, 2023
Axons are processes of neurons, up to a metre long, that form the essential biological cables wiring nervous systems. They must survive, often far away from their cell bodies and up to a century in humans.
Gaynor Smith, Sean T. Sweeney, Cahir J. O’Kane, Andreas Prokop   +3 more
doaj   +1 more source

Prediction of protein-protein interactions using one-class classification methods and integrating diverse data [PDF]

, 2007
This research addresses the problem of prediction of protein-protein interactions (PPI) when integrating diverse kinds of biological information. This task has been commonly viewed as a binary classification problem (whether any two proteins do or do ...
Gilbert, D, Reyes, J A
core   +3 more sources

Combined endurance and resistance exercise training alters the spatial transcriptome of skeletal muscle in young adults

iScience
Summary: Chronic exercise training substantially improves skeletal muscle function and performance. The repeated demands and stressors of each exercise bout drive coordinated molecular adaptations within multiple cell types, leading to enhanced ...
Michael J. Stec, Zachary A. Graham, Qi Su, Christina Adler, Min Ni, Valerie Le Rouzic, David R. Golann, Patrick J. Ferrara, Gabor Halasz, Mark W. Sleeman, Kaleen M. Lavin, Timothy J. Broderick, Marcas M. Bamman   +12 more
doaj   +1 more source

The pleiotropic ABNORMAL FLOWER AND DWARF1 affects plant height, floral development and grain yield in rice

Journal of Integrative Plant Biology, 2016
Moderate plant height and successful establishment of reproductive organs play pivotal roles in rice grain production. The molecular mechanism that controls the two aspects remains unclear in rice.
Deyong Ren, Yuchun Rao, Liwen Wu, Qiankun Xu, Zizhuang Li, Haiping Yu, Yu Zhang, Yujia Leng, Jiang Hu, Li Zhu, Zhenyu Gao, Guojun Dong, Guangheng Zhang, Longbiao Guo, D. Zeng, Q. Qian   +15 more
semanticscholar   +1 more source

Interferon gamma induced-ACSL5 shapes the lipidome of kidney tubular cells

iScience
Summary: Acyl-CoA synthetase long-chain family (ACSL) enzymes are critical in the activation of long-chain fatty acid. To determine the regulatory mechanisms of ACSL5 and its biological functions within the kidney tubule, we generated transcriptomic ...
Virginie Poindessous, Julio L. Sampaio, Lydia Bouidghaghen, Ivan Nemazanyy, Alexandre Pallet, Maarten Naesens, Thibaut Vaulet, Dany Anglicheau, Nicolas Pallet   +8 more
doaj   +1 more source

Interactive Multiresolution Visualization of Cellular Network Processes

iScience, 2020
Summary: Visualization plays a central role in the analysis of biochemical network models to identify patterns that arise from reaction dynamics and perform model exploratory analysis.
Oscar O. Ortega, Carlos F. Lopez
doaj   +1 more source

Minimum Information About a Simulation Experiment (MIASE) [PDF]

, 2011
Reproducibility of experiments is a basic requirement for science. Minimum Information (MI) guidelines have proved a helpful means of enabling reuse of existing work in modern biology. The Minimum Information Required in the Annotation of Models (MIRIAM)
Hucka, Michael, Waltemath, Dagmar
core   +3 more sources