Results 111 to 120 of about 53,983 (298)
Interactome and transcriptome data.
, 2021 Data sheet 1: Tax interactome data from this work and previous studies. Data sheet 2: HBZ interactome data from this work and previous studies. Data sheet 3: Results of the Y2H screen for Tax and mutant constructs. Data sheet 4: Results of the Y2H screen
Benoit Charloteaux (87758) +24 more
core +1 more source
Advanced Science, EarlyView.Ex‐spRandom is a spatial transcriptomics platform that synergizes random‐primed chemistry with iterative hydrogel expansion. By physically decrowding the dense FFPE matrix, this scalable technology shatters the traditional resolution‐sensitivity barrier.
Shunji Zhang +7 more
wiley +1 more source
Towards a yeast reference interactome [PDF]
, 2015 Despite an increasing number of interactomic datasets already available for model organisms and humans, many aspects remain contradictory, debatable or unclear due to the lack of complete high-quality networks.
Desbuleux, Alice
core
Inter-Tools: a toolkit for interactome analysis
, 2017 Interactome analysis is an increasingly useful tool for discovering disease pathways. However, protein interaction data is scattered among different sources, and researchers must often sift through several large repositories before beginning a project ...
Jose Ordovas +2 more
core +1 more source
Advanced Science, EarlyView.A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo +10 more
wiley +1 more source
Hepatitis C virus infection protein network
Molecular Systems Biology, 2008 A proteome‐wide mapping of interactions between hepatitis C virus (HCV) and human proteins was performed to provide a comprehensive view of the cellular infection.
B de Chassey +21 more
doaj +1 more source
Advanced Science, EarlyView.Radiation triggers glycolytic reprogramming in alveolar epithelial type II cells, causing pathological lactate accumulation. This metabolic stress drives p300‐mediated H3K18 lactylation at the VIRMA promoter, activating transcription. Elevated VIRMA enriches m6A on GATA3 mRNA, which YTHDF1 stabilizes, ultimately driving epithelial–mesenchymal ...
Junxuan Yi +8 more
wiley +1 more source
Advanced Science, EarlyView.In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang +11 more
wiley +1 more source
Advanced Science, EarlyView.Uhrf1‐mediated PKM2 ubiquitination and degradation repressed the nuclear translocation of PKM2, and EPT served as a molecular glue capable of targeting the Uhrf1–PKM2 complex to alleviate the IBD course, suggesting that the Uhrf1–PKM2 axis was a previously unrecognized strategy for treating IBD.
Juan Zhang +9 more
wiley +1 more source
Advanced Science, EarlyView.D4F‐functionalized ceria nanozyme–CasRx nanoparticles preferentially target renal macrophages through SR‐B1‐mediated uptake in ischemia–reperfusion injury. Ceria scavenges excessive ROS, while CasRx silences STING signaling, shifting macrophages toward a less inflammatory, pro‐resolving state and increasing the proportion of regulatory T cells.
Weibo Chen +11 more
wiley +1 more source