Results 121 to 130 of about 63,382 (353)

ligand-discovery/interactome-signatures: Publication release

open access: yes
Interactome signature modeling for the Ligand Discovery ...
Miquel Duran-Frigola
core   +1 more source

The synthesis interactome (SI).

open access: yes, 2018
The synthesis interactome (SI).
Octavio Martínez (184407)   +1 more
core   +1 more source

FGF13 Deficiency Ameliorates Paclitaxel‐Induced Neuropathic Pain by Inhibiting VASH1‐Mediated Microtubule Detyrosination to Promote Mitophagy

open access: yesAdvanced Science, EarlyView.
FGF13 is upregulated in DRG neurons of PIPNP model mice. DRG neuron‐specific knockout of FGF13 ameliorates PIPNP symptoms. Mechanistically, FGF13 potentiates microtubule detyrosination by promoting VASH1 binding to microtubules. FGF13 knockout suppresses VASH1‐mediated microtubule detyrosination and promotes α‐tubulin tyrosination.
Yiming Dong   +10 more
wiley   +1 more source

The BioPlex Network: A Systematic Exploration of the Human Interactome

open access: yesCell, 2015
SUMMARY Protein interactions form a network whose structure drives cellular function and whose organization informs biological inquiry. Using high-throughput affinity-purification mass spectrometry, we identify interacting partners for 2,594 human ...
Edward L. Huttlin   +30 more
semanticscholar   +1 more source

Functional interactome of Aquaporin 1 sub-family reveals new physiological functions in Arabidopsis Thaliana [PDF]

open access: yes, 2013
Aquaporins are channel proteins found in plasma membranes and intercellular membranes of different cellular compartments, facilitate the water flux, solutes and gases across the cellular plasma membranes.
Jasmin Sutkovic   +2 more
core  

Pur α Interactome.

open access: yes, 2013
Pur α Interactome.
Abrar Qurashi (37031)   +4 more
core   +1 more source

UCHL3 Regulates Subgenomic Flaviviral RNA Condensates to Promote Virus Propagation

open access: yesAdvanced Science, EarlyView.
ABSTRACT Flavivirus subgenomic RNAs (sfRNAs) antagonise antiviral defences, yet how sfRNAs are organized and maintained in cells remains poorly understood. Here we identify ubiquitin C‐terminal hydrolase L3 (UCHL3) as a post‐translational regulator of flavivirus sfRNA stability and function.
Oscar Trejo‐Cerro   +7 more
wiley   +1 more source

Porcine Epidemic Diarrhea Virus (PEDV) ORF3 Interactome Reveals Inhibition of Virus Replication by Cellular VPS36 Protein

open access: yesViruses, 2019
The accessory protein ORF3 of porcine epidemic diarrhea virus (PEDV) has been proposed to play a key role in virus replication. However, our understanding of its function regarding virus and host interaction is still limited.
Challika Kaewborisuth   +3 more
doaj   +1 more source

Glycosaminoglycan–Protein Interactions: The First Draft of the Glycosaminoglycan Interactome

open access: yesJournal of Histochemistry and Cytochemistry, 2020
The six mammalian glycosaminoglycans (GAGs), chondroitin sulfate, dermatan sulfate, heparin, heparan sulfate, hyaluronan, and keratan sulfate, are linear polysaccharides. Except for hyaluronan, they are sulfated to various extent, and covalently attached
Sylvain D. Vallet   +2 more
semanticscholar   +1 more source

Estimated interactome coverages and interactome sizes.

open access: yes, 2012
We report the means and standard deviations for the reciprocal hits data over all the -value thresholds that we investigate. These results assume that the S. cerevisiae interactome is complete at interactions.
Charlotte M. Deane (50371)   +3 more
core   +1 more source

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