Results 41 to 50 of about 118,295 (302)

Use of interferon gamma release assay to assess latent tuberculosis infection among healthcare workers in Hong Kong [PDF]

, 2015
Key Messages 1. Overall baseline interferon gamma release assay positivity was 20.7%. 2. The conversion to interferon gamma release assay positivity at 3 months was 8.85% in the exposed group and 4.54% in the non-exposed group using the conventional ...
Chan, JWM, Chu, CM, Fung, SC, Lai, CKC, Lam, BHS, Mok, YW, Ng, TK, Seto, WH, Tsang, DNC, Yam, WC   +9 more
core  

Screening for Tuberculosis in Health Care Workers. Experience in an Italian Teaching Hospital [PDF]

, 2017
Health care workers (HCW) are particularly at risk of acquiring tuberculosis (TB), even in countries with low TB incidence. Therefore, TB screening in HCW is a useful prevention strategy in countries with both low and high TB incidence.
De Luca, Assunta, DI NINNO, Filippo, Ferretti, Filippo, Marani, Alessandra, Napoli, Christian, Orioli, Riccardo, Orsi, Giovanni Battista, Prestigiacomo, Claudio, Sarlo, MARIA GIUDITTA   +8 more
core   +3 more sources

Diagnostic Utility of Interferon-Gamma Release Assay in Tuberculous Lymphadenitis [PDF]

Chinese Medical Sciences Journal, 2019
Objective The aim of this study was to evaluate the diagnostic performance of T-SPOT.TB for tuberculous lymphadenitis. Methods Suspected tuberculous lymphadenitis patients between September 2010 and September 2018 who had both peripheral blood T-SPOT.TB test and lymph node biopsy were retrospectively enrolled in this study.
Xin-Chao, Liu, Su-Su, Ye, Wen-Ze, Wang, Yue-Qiu, Zhang, Li-Fan, Zhang, Xiao-Cheng, Pan, Zi-Yue, Zhou, Miao-Yan, Zhang, Jiang-Hao, Liu, Zhi-Yong, Liang, Xiao-Qing, Liu   +10 more
openaire   +2 more sources

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Tuberculin test versus interferon gamma release assay in pregnant women with household contacts of tuberculosis patients

International Journal of Mycobacteriology, 2022
Background: Pregnant women who live in tuberculosis (TB)-affected households are more likely to develop latent TB infection (LTBI), which often escapes treatment.
Maisuri Tadjuddin Chalid, Dian Puspawaty, Andi Mardiah Tahir, Hidayah Najdah, Muhammad Nasrum Massi   +4 more
doaj   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Multicenter clinical evaluation of three commercial reagent kits based on the interferon-gamma release assay for the rapid diagnosis of tuberculosis in China

International Journal of Infectious Diseases, 2015
Objective: To evaluate the performance of three interferon-gamma release assay (IGRA) kits in detecting Mycobacterium tuberculosis infection in China.
Yan Qiu, Yansen Wang, Nan Lin, Mingxiang Huang, Yunhong Tan, Qing Wang, Yi Jiang, Haican Liu, Jiao Liu, Jingrui Zhang, Jue Wang, Xinchan Chen, Dongping Wang, Guilian Li, Zhongnan Chen, Lishui Zhang, Dixun Bao, Lili Zhao, Chaxiang Guan, Kanlgin Wan   +19 more
doaj   +1 more source

Performance of interferon-γ release assay in the diagnosis of tuberculous lymphadenitis: a meta-analysis [PDF]

PeerJ, 2017
Background The diagnostic values of interferon-gamma release assays (IGRA) in tuberculosis (TB) vary a lot with different site of infections, with especially higher sensitivities in chronic forms of TB such as tuberculosis of the lymph node. We conducted
Qianqian Liu, Wenzhang Li, Yunfeng Chen, Xinmiao Du, Chengdi Wang, Binmiao Liang, Yin Tang, Yulin Feng, Chuanmin Tao, Jian-Qing He   +9 more
doaj   +2 more sources

Serial Interferon-Gamma Release Assay (IGRA) Testing to Monitor Treatment Responses in Cases of Feline Mycobacteriosis

Pathogens, 2021
The interferon-gamma release assay (IGRA) is used to diagnose cases of feline mycobacteriosis, but the use of serial testing to monitor treatment responses has not been evaluated in this species.
Jordan L. Mitchell, Conor O’Halloran, Paul Stanley, Kieran McDonald, Paul Burr, Danièlle A. Gunn-Moore, Jayne C. Hope   +6 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source