Results 101 to 110 of about 10,873 (167)

Human but not mouse hepatocytes respond to interferon-lambda in vivo.

PLoS ONE, 2014
The type III interferon (IFN) receptor is preferentially expressed by epithelial cells. It is made of two subunits: IFNLR1, which is specific to IFN-lambda (IFN-λ) and IL10RB, which is shared by other cytokine receptors.
Pascale Hermant, Céline Demarez, Tanel Mahlakõiv, Peter Staeheli, Philip Meuleman, Thomas Michiels   +5 more
doaj   +1 more source

Regulatory B cells in the central nervous system: From immune regulation to neuroprotection

Neuroprotection, Volume 4, Issue 1, Page 4-13, March 2026.
Neuroinflammatory mechanisms and the therapeutic potential of regulatory B cells (Bregs). Following brain Injury (left panel) blood–brain barrier disruption facilitates the infiltration of peripheral leukocytes, including effector B cells (Beff) and effector T cells (Teff). This process triggers the activation of macrophages, astrocytes, and microglia,
Luiza Stanaszek, Miroslaw Janowski
wiley   +1 more source

The first trimester human placenta responds to Zika virus infection inducing an interferon (IFN) and antiviral interferon stimulated gene (ISG) response

Virology Journal
Background Zika virus (ZIKV) is a positive-strand RNA virus of the Flaviviridae family. Maternal ZIKV infection during pregnancy can spread to the placenta and fetus causing severe neurological defects and infants born with microcephaly.
Kylie H. Van der Hoek, Tanja Jankovic-Karasoulos, Dylan McCullough, Rosa C. Coldbeck-Shackley, Nicholas S. Eyre, Claire T. Roberts, Michael R. Beard   +6 more
doaj   +1 more source

A Comparison of Monte Carlo Based Marginal Likelihood Estimators

WIREs Computational Statistics, Volume 18, Issue 1, March 2026.
Comparison of marginal likelihood estimation methods. ABSTRACT Marginal likelihood plays a central role in Bayesian model comparison and hypothesis testing, but its computation is often challenging in practice. This article reviews recent Monte Carlo methods that rely on the availability of Markov chain Monte Carlo (MCMC) samples from the posterior and
Aolan Li, Pang‐Yu Liu, Yu‐Bo Wang, Analisa Milkey, Paul O. Lewis, Ming‐Hui Chen   +5 more
wiley   +1 more source

The dysregulation of innate immunity by Porphyromonas gingivalis in the etiology of Alzheimer's disease

Journal of Internal Medicine, Volume 299, Issue 3, Page 328-348, March 2026.
Abstract The etiology of Alzheimer's disease (AD) remains under active debate. In this perspective, we explore the hypothesis that a primarily infection‐caused chronic dysregulation and weakening of human innate immunity via the underexpression, degradation, and inactivation of innate immune proteins necessary for direct antimicrobial effects and ...
Annelise E. Barron, Jennifer S. Lin, Mark I. Ryder, Peter Bergman   +3 more
wiley   +1 more source

The Interferon-Lambda Family Celebrates 20 Years of Scientific Discovery. [PDF]

J Interferon Cytokine Res, 2023
Donnelly RP, Prokunina-Olsson L.
europepmc   +1 more source

Deletion of Interferon Lambda Receptor Elucidates Susceptibility to the Murine Model of Biliary Atresia. [PDF]

J Interferon Cytokine Res, 2023
Hartman SJ, Weiss MA, Temple HM, Donnelly B, Pasula R, Poling HM, McNeal M, Mohanty SK, Tiao GM.   +8 more
europepmc   +1 more source

Identification of a Novel Interferon Lambda Splice Variant in Chickens. [PDF]

J Virol, 2023
Chen J, Li P, Zou W, Jiang Y, Li L, Hao P, Gao Z, Qu Q, Pang Z, Zhuang X, Nan F, Jin N, Du S, Li C.   +13 more
europepmc   +1 more source

Interferon Lambda-4 [PDF]

, 2020
openaire   +1 more source

Potential of Interferon Lambda as an Inhibitor of SARS-CoV-2. [PDF]

Mol Biol, 2023
Oleinik LA, Madonov PG, Pykhtina MB.
europepmc   +1 more source