Results 41 to 50 of about 260,978 (210)
Influenza virus activation of the interferon system [PDF]
, 2015 This study was supported by the Wellcome Trust (grant number 087751/A/08/Z) and the Medical Research Council (grant number G0700848).The host interferon (IFN) response represents one of the first barriers that influenza viruses must surmount in order to ...
Fodor, Ervin +8 more
core +1 more source
COVID‐19: lambda interferon against viral load and hyperinflammation
EMBO Molecular Medicine, 2020 Coronavirus disease 2019 (COVID‐19), triggered by the betacoronavirus SARS‐CoV‐2, has become one of the worst pandemics of our time that has already caused more than 250,000 deaths (JHU data‐05/06/2020, https://coronavirus.jhu.edu/ ).
Evangelos Andreakos, Sotirios Tsiodras
doaj +1 more source
mSphere of Influence: Interferon Ultra Is a Means To Fight Viral Disease
mSphere, 2020 Connor G. G. Bamford works in the fields of virology and innate immunity. In this mSphere of Influence article, he reflects on how three papers by Manry et al. (J. Manry, G. Laval, E. Patin, S.
Connor G. G. Bamford
doaj +1 more source
PLoS ONE, 2016 BackgroundHepatitis C virus infection is a global health problem. New direct-acting antiviral agents have been recently approved. However, due to their high cost and some genotypes remaining difficult to treat, interferon-based therapy with pegylated ...
Ran Chen +4 more
doaj +1 more source
Bunyaviruses and the type I interferon system [PDF]
, 2009 The family Bunyaviridae contains more than 350 viruses that are distributed throughout the world. Most members of the family are transmitted by arthopods, and several cause disease in man, domesticated animals and crop plants. Despite being recognized as
Richard M. Elliott +7 more
core +1 more source
Interferon signaling in viral hepatitis [PDF]
, 2013 Hepatitis C virus (HCV) is a single stranded positive RNA virus classified in 6 different genotypes. Hepatocytes are the main targets of HCV infection. It has been estimated that 60 to 70% of the infected patients develop chronic infection.
Trincucci, Gaia
core +1 more source
Journal of Inflammation Research, 2021 Scott A Read,1– 3 Brian S Gloss,4 Christopher Liddle,3 Jacob George,3 Golo Ahlenstiel1– 3 1Blacktown Clinical School, Western Sydney University, Blacktown, NSW, 2148, Australia; 2Blacktown Hospital, WSLHD, Blacktown, NSW, 2148, Australia ...
Read SA +4 more
doaj
Simulation in the call-by-need lambda-calculus with letrec [PDF]
, 2010 This paper shows the equivalence of applicative similarity and contextual approximation, and hence also of bisimilarity and contextual equivalence, in the deterministic call-by-need lambda calculus with letrec.
Sabel, David +2 more
core +1 more source
IFNλ is a potent anti‐influenza therapeutic without the inflammatory side effects of IFNα treatment
EMBO Molecular Medicine, 2016 Influenza A virus (IAV)‐induced severe disease is characterized by infected lung epithelia, robust inflammatory responses and acute lung injury.
Sophia Davidson +7 more
doaj +1 more source
Interferon lambda 1 is associated with dengue severity in Thailand
International Journal of Infectious Diseases, 2020 Objectives: Patients with dengue exhibit a range of symptoms from an acute febrile illness (dengue fever, DF), to dengue hemorrhagic fever (DHF), and to the most severe outcome, dengue shock syndrome (DSS).
Unchana Arayasongsak +8 more
doaj +1 more source