IRF1 (interferon regulatory factor 1) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on IRF1 (interferon regulatory factor 1), with data on DNA, on the protein encoded, and where the gene is implicated.
P Palladinetti, G Symonds, A Dolnikov
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Interferon regulatory factor 1‐triggered free ubiquitin protects the intestines against radiation‐induced injury via CXCR4/FGF2 signaling [PDF]
MedComm, 2022 Radiation‐induced intestinal injury is a serious concern during abdominal and pelvic cancers radiotherapy. Ubiquitin (Ub) is a highly conserved protein found in all eukaryotic cells.
Yang Jiao +16 more
doaj +2 more sources
Calpeptin may reverse glucocorticoid-resistance of allergic rhinitis associated with cigarette smoke exposure by down-regulating interferon regulatory factor 1 [PDF]
Heliyon, 2023 Cigarette smoke exposure is an important factor in chronic inflammation in patients with allergic rhinitis (AR); however, the relationship between cigarette smoke and AR-related glucocorticoid resistance requires further study.
Wen-Xuan Zhu +10 more
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Interferon‐regulatory factor‐1 boosts bevacizumab cardiotoxicity by the vascular endothelial growth factor A/14‐3‐3γ axis [PDF]
ESC Heart FailureAim Myocardial injury is a significant cause of death. This study investigated the role and underlying mechanism of interferon‐regulatory factor‐1 (IRF1) in bevacizumab (BVZ)‐induced cardiomyocyte injury.
Xuan‐Ying Chen +5 more
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Interferon regulatory factor 1 inactivation in human cancer. [PDF]
Biosci Rep, 2018 Interferon regulatory factors (IRFs) are a group of closely related proteins collectively referred to as the IRF family. Members of this family were originally recognized for their roles in inflammatory responses; however, recent research has suggested that they are also involved in tumor biology.
Alsamman K, El-Masry OS.
europepmc +4 more sources
Loss of interferon regulatory factor-1 prevents lung fibrosis by upregulation of pon1 expression [PDF]
Respiratory ResearchBackground Interferon regulatory factor-1 (IRF1) is a transcription factor that plays a significant role in various biological processes, including inflammatory injury, viral infection, cell death, and immune responses, and it has been extensively ...
Aiyuan Zhou +9 more
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Role of Interferon Regulatory Factor 1 in acute and chronic virus infections. [PDF]
VirologyDecades of research have defined the function of interferon regulatory factors (IRFs) in the antiviral immune response. Interferon regulatory factor-1 (IRF-1) is the founding member of the IRF family, with recognized antiviral effects across diverse virus infections. While most antiviral activities of IRF-1 were defined in vitro, fewer studies examined
Rahlf CR, Tarakanova VL.
europepmc +4 more sources
Neural Regeneration ResearchInterferon regulatory factor 7 plays a crucial role in the innate immune response. However, whether interferon regulatory factor 7-mediated signaling contributes to Parkinson’s disease remains unknown.
Shengyang Zhou +10 more
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Interferon regulatory factor 7 mediates obesity-associated MCP-1 transcription. [PDF]
PLoS ONE, 2020 Hypertrophy, associated with adipocyte dysfunction, causes increased pro-inflammatory adipokine, and abnormal glucose and lipid metabolism, leading to insulin resistance and obesity-related-health problems.
Masashi Kuroda +12 more
doaj +3 more sources
The Modulation of Interferon Regulatory Factor-1 via Caspase-1-Mediated Alveolar Macrophage Pyroptosis in Ventilator-Induced Lung Injury [PDF]
Mediators of Inflammation, 2022 Background. To examine the role of interferon regulatory factor-1 (IRF-1) and to explore the potential molecular mechanism in ventilator-induced lung injury. Methods.
Minhui Dai, Qian Li, Pinhua Pan
doaj +2 more sources