Results 11 to 20 of about 9,208,925 (289)
Viral interferon regulatory factors. [PDF]
J Interferon Cytokine Res, 2009 Upon viral infection, the major defensive strategy employed by the host immune system is the activation of the interferon (IFN)-mediated antiviral pathway, which is overseen by IFN regulatory factors (IRFs). In order to complete their life cycles, viruses must find a way to modulate the host IFN-mediated immune response.
Lee HR +4 more
europepmc +5 more sources
Interferon regulatory factor 7 in inflammation, cancer and infection [PDF]
Frontiers in Immunology, 2023 Interferon regulatory factor 7 (IRF7), a member of the interferon regulatory factors (IRFs) family, is located downstream of the pattern recognition receptors (PRRs)-mediated signaling pathway and is essential for the production of type I interferon (IFN-
Furong Qing, Zhiping Liu
doaj +2 more sources
Rhadinoviral interferon regulatory factor homologues
Biological Chemistry, 2017 Abstract Kaposi’s sarcoma-associated herpesvirus (KSHV), or human herpesvirus 8 (HHV8) is a gammaherpesvirus and the etiological agent of Kaposi’s sarcoma, primary effusion lymphoma and multicentric Castleman disease. The KSHV genome contains genes for a unique group of proteins with homology to cellular interferon regulatory factors, termed viral ...
Sandra Koch, Thomas F. Schulz
openaire +3 more sources
Poxviral Targeting of Interferon Regulatory Factor Activation [PDF]
Viruses, 2020 As viruses have a capacity to rapidly evolve and continually alter the coding of their protein repertoires, host cells have evolved pathways to sense viruses through the one invariable feature common to all these pathogens—their nucleic acids. These genomic and transcriptional pathogen-associated molecular patterns (PAMPs) trigger the activation of ...
Lawler, Clara, Brady, Gareth
openaire +7 more sources
IRF6 Genetic Variation and Maternal Smoking During Pregnancy in Cleft Lip/Palate
Frontiers in Dental Medicine, 2021 The goal of the present work was to revisit published data to test if genetic variation in interferon regulatory factor 6 (IRF6) is associated with children born with cleft lip with or without cleft palate (CL/P) for cases with positive history of ...
Alexandre R. Vieira +4 more
doaj +1 more source
Frontiers in Marine Science, 2022 Interferon regulatory factors (IRFs) are a family of transcription factors that control many facets during innate and adaptive immune responses. Vertebrate IRFs play important roles in regulating the expression of interferons (IFNs) and IFN-stimulated ...
Naina Hu +15 more
doaj +1 more source
Prognostic significance and multidimensional roles of interferon regulatory factors in cancer biology: A comprehensive analysis [PDF]
Genes and DiseasesGuo Ji +11 more
doaj +2 more sources
Fermentation, 2023 Lactic acid bacteria (LAB) form a group of bacteria to which most probiotics belong and are commonly found in fermented dairy products. Fermented foods and beverages are foods made through desired microbial growth and enzymatic conversions of food ...
Seyoum Gizachew +8 more
doaj +1 more source
Fishes, 2023 Interferon regulatory factors (IRFs) play crucial roles in antiviral processes, such as in the transcriptional induction of interferon (IFN) and IFN-stimulated genes (ISGs). In this study, the genes encoding IRF5 and IRF6 were identified in Pagrus major,
Kyung-Ho Kim +6 more
doaj +1 more source
The Role of Interferon Regulatory Factors in Liver Diseases. [PDF]
Int J Mol SciThe interferon regulatory factors (IRFs) family comprises 11 members that are involved in various biological processes such as antiviral defense, cell proliferation regulation, differentiation, and apoptosis. Recent studies have highlighted the roles of IRF1-9 in a range of liver diseases, including hepatic ischemia–reperfusion injury (IRI), alcohol ...
Zeng C, Zhu X, Li H, Huang Z, Chen M.
europepmc +3 more sources