Results 41 to 50 of about 2,200,720 (269)
Exploring the Potentiality of a Plant Platform for Monoclonal Antibody Production in Veterinary Medicine [PDF]
VaccinesCanine atopic dermatitis (CAD) is an allergic, inflammatory, and pruritic skin disease associated with the production of IgE antibodies against environmental allergens and mainly house dust mite allergens.
Bertrand Morel +7 more
doaj +3 more sources
Interleukin‐31 and interleukin‐31 receptor: New therapeutic targets for atopic dermatitis [PDF]
Experimental Dermatology, 2018 AbstractAtopic dermatitis (AD) is characterized by chronic, eczematous, severe pruritic skin lesions caused by skin barrier dysfunction and T helper (Th)2 cell‐mediated immunity. Interleukin (IL)‐31 is a potent pruritogenic cytokine primarily produced by Th2 cells.
C. Nakashima, A. Otsuka, K. Kabashima
semanticscholar +3 more sources
Blockage of the IL-31 Pathway as a Potential Target Therapy for Atopic Dermatitis
Pharmaceutics, 2023 Atopic dermatitis (AD), a pruritic, inflammatory chronic disease with multifactorial pathogenesis, has been a therapeutic challenge. Novel target treatments aim to reduce not only the immunologic dysfunction and microbiome dysbiosis but also the recovery
Raquel Leao Orfali, Valeria Aoki
doaj +1 more source
Veterinary Immunology and Immunopathology, 2023 Lokivetmab (Cytopoint®, Zoetis) is a canine monoclonal antibody that specifically binds and neutralizes interleukin (IL)-31. Lokivetmab is approved for use in dogs for the treatment of atopic dermatitis (AD) and allergic dermatitis. The laboratory safety
M. Krautmann +15 more
semanticscholar +1 more source
The Protective Effects of IL-31RA Deficiency During Bleomycin-Induced Pulmonary Fibrosis
Frontiers in Immunology, 2021 Idiopathic Pulmonary Fibrosis (IPF) is a severe fibrotic lung disease characterized by excessive collagen deposition and progressive decline in lung function.
Dan J. K. Yombo +8 more
doaj +1 more source
IL-31 and IL-33 in rheumatoid arthritis patients
Научно-практическая ревматология, 2022 Objective – to investigate clinical and diagnostic significance of IL-31 and IL-33 determination in patients with rheumatoid arthritis (RA).Material and methods. 154 patients with a reliable diagnosis of RA were examined.
N. A. Lapkina +8 more
doaj +1 more source
Funktionelle Aktivierung von eosinophilen Granulozyten durch Interleukin-31 [PDF]
, 2021 Kunsleben, Nikola
core +2 more sources
Veterinary Sciences, 2023 Pruritic models in healthy dogs utilizing intravenous administration of interleukin 31 (IL-31) bypass the “natural” itch sensation in AD, which is initiated by pruriceptive primary afferent neurons in the skin.
Jason Pearson +5 more
doaj +1 more source
Toxins, 2022 Chronic-kidney-disease-associated pruritus (CKD-aP) is one of the most common and burdensome dermatological symptoms affecting patients undergoing dialysis, and its etiopathogenesis has still not been fully discovered.
Karolina Świerczyńska +5 more
doaj +1 more source
Allergologia et Immunopathologia, 2022 BACKGROUND Itching is one of the major and mandatory signs of atopic dermatitis (AD) in children. Interleukin 31 (IL-31) is strongly involved in the genesis of pruritus.
E. Duca +4 more
semanticscholar +1 more source