Results 21 to 30 of about 56,984,652 (272)

Evaluation of Interleukin-31 Serum Levels in Patients with Chronic Kidney Disease on Hemodialysis with and without Uremic Pruritus [PDF]

open access: yesمجلة كلية الطب
Background: Interleukin-31 has been linked with developing and maintaining pruritus in various dermatological and non-dermatological diseases. Objectives: To evaluate interleukin-31 serum levels in hemodialysis patients with and without uremic ...
Mustafa Sh. Abdulqahar, Ali A. Kasem
doaj   +2 more sources

Interleukin-31: A Novel Diagnostic Marker of Allergic Diseases

open access: yesCurrent Allergy and Asthma Reports, 2014
Interleukin-31 (IL-31) is a newly discovered cytokine associated with chronic skin inflammation and pruritus. Patients with atopic dermatitis, chronic spontaneous urticaria, allergic contact dermatitis, prurigo nodularis, primary cutaneous lymphoma and mastocytosis exhibit increased serum levels of IL-31 protein and elevated IL-31 mRNA in the skin ...
Rabenhorst, Anja, Hartmann, Karin
openaire   +4 more sources

Regulation of Th2 responses by different cell types expressing the interleukin-31 receptor [PDF]

open access: yesAllergy, Asthma & Clinical Immunology, 2017
Background Interleukin-31 (IL-31) is a recently identified cytokine produced by Th2 cells that is involved in the development of atopic dermatitis-induced skin inflammation and pruritus.
Saburo Saito   +6 more
doaj   +2 more sources

Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies [PDF]

open access: yes, 2012
BACKGROUND: Persistent inflammation has been proposed to contribute to various stages in the pathogenesis of cardiovascular disease. Interleukin-6 receptor (IL6R) signalling propagates downstream inflammation cascades.
Thomas, GN   +489 more
core   +5 more sources

Blockage of the IL-31 Pathway as a Potential Target Therapy for Atopic Dermatitis

open access: yesPharmaceutics, 2023
Atopic dermatitis (AD), a pruritic, inflammatory chronic disease with multifactorial pathogenesis, has been a therapeutic challenge. Novel target treatments aim to reduce not only the immunologic dysfunction and microbiome dysbiosis but also the recovery
Raquel Leao Orfali, Valeria Aoki
doaj   +1 more source

The Protective Effects of IL-31RA Deficiency During Bleomycin-Induced Pulmonary Fibrosis

open access: yesFrontiers in Immunology, 2021
Idiopathic Pulmonary Fibrosis (IPF) is a severe fibrotic lung disease characterized by excessive collagen deposition and progressive decline in lung function.
Dan J. K. Yombo   +8 more
doaj   +1 more source

IL-31 and IL-33 in rheumatoid arthritis patients

open access: yesНаучно-практическая ревматология, 2022
Objective – to investigate clinical and diagnostic significance of IL-31 and IL-33 determination in patients with rheumatoid arthritis (RA).Material and methods. 154 patients with a reliable diagnosis of RA were examined.
N. A. Lapkina   +8 more
doaj   +1 more source

Interleukin‐31: The “itchy” cytokine in inflammation and therapy [PDF]

open access: yesAllergy, 2020
AbstractThe cytokine interleukin‐31 has been implicated in the pathophysiology of multiple atopic disorders such as atopic dermatitis (AD), allergic rhinitis, and airway hyper‐reactivity. In AD, IL‐31 has been identified as one of the main “drivers” of its cardinal symptom, pruritus.
Angeliki Datsi   +4 more
openaire   +3 more sources

Emerging role of interleukin‐31 and interleukin‐31 receptor in pruritus in atopic dermatitis [PDF]

open access: yesAllergy, 2017
AbstractAtopic dermatitis (AD) is a chronic or chronically relapsing, eczematous, severely pruritic skin disorder associated with skin barrier dysfunction. The lesional skin of AD exhibits T helper 2 (TH2)‐deviated immune reactions. Interleukin‐31 (IL‐31), preferentially produced from TH2 cells, is a potent pruritogenic cytokine, and its systemic and ...
M. Furue   +4 more
openaire   +2 more sources

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