Results 21 to 30 of about 3,930,798 (267)
The antiangiogenic role of the pro-inflammatory cytokine interleukin-31 [PDF]
Oncotarget, 2017 Pro-inflammatory cytokines in the tumor microenvironment are known for their ability to either inhibit or promote cancer progression. Here we evaluated the role of Interleukin-31 (IL31), a protein belonging to the pro-inflammatory IL-6 cytokine family which has been characterized in autoimmune disease, in tumorigenesis.
Shiri Davidi +8 more
openaire +4 more sources
Increased levels of interleukin 31 (IL-31) in osteoporosis [PDF]
BMC Immunology, 2015 Several inflammatory cytokines play a key part in the induction of osteoporosis. Until now, involvement of the Th2 cytokine interleukin-31 (IL-31) in osteoporosis hadn't yet been studied. IL-31 is a proinflammatory cytokine mediating multiple immune functions, whose involvement in a wide range of diseases, such as atopic dermatitis, inflammatory bowel ...
GINALDI, Lia +6 more
openaire +5 more sources
Association of mastocytosis with interleukin 31 gene polymorphism [PDF]
Clinical and Translational Allergy, 2015 Mastocytosis is a rare disease characterized by activating KIT mutations and clonal expansion of mast cells (MCs) in tissues, particularly in skin and bone marrow. Symptoms of mastocytosis always correlate with the extent of MC infiltration and include urticaria pigmentosa, anaphylaxis, flushing, headache, diarrhea, osteoporosis and pruritus ...
Nedoszytko, Boguslaw +3 more
openaire +2 more sources
Eosinophils are a Major Source of Interleukin-31 in Bullous Pemphigoid
Acta Dermato-Venereologica, 2018 Bullous pemphigoid (BP) is characterized by substantial skin and blood eosinophilia as well as intensive pruritus. Since the pruritogenic cytokine interleukin (IL)-31 is increased in inflammatory skin diseases the aim of this study was to determine ...
Urda Rüdrich +9 more
doaj +5 more sources
Interleukin-31 expression and relation to disease severity in human asthma [PDF]
Scientific Reports, 2016 AbstractInterleukin 31 (IL-31) is a novel T helper type 2 effector cytokine that plays an important role in the pathogenesis of allergic diseases. However, its role in human asthma remains unclear. The aim of this study was to measure IL-31 levels in the serum, bronchoalveolar lavage fluid (BALF) and bronchial tissue of asthmatics and healthy subjects ...
Tianwen Lai +10 more
openaire +3 more sources
Regulation of Th2 responses by different cell types expressing the interleukin-31 receptor [PDF]
Allergy, Asthma & Clinical Immunology, 2017 Background Interleukin-31 (IL-31) is a recently identified cytokine produced by Th2 cells that is involved in the development of atopic dermatitis-induced skin inflammation and pruritus.
Saburo Saito +6 more
doaj +2 more sources
Tuning SLOCK toward Chronic Disease Diagnostics and Management: Label-free Sweat Interleukin-31 Detection [PDF]
ACS Omega, 2021 Sayali Upasham, Shalini Prasad
doaj +2 more sources
Blockage of the IL-31 Pathway as a Potential Target Therapy for Atopic Dermatitis
Pharmaceutics, 2023 Atopic dermatitis (AD), a pruritic, inflammatory chronic disease with multifactorial pathogenesis, has been a therapeutic challenge. Novel target treatments aim to reduce not only the immunologic dysfunction and microbiome dysbiosis but also the recovery
Raquel Leao Orfali, Valeria Aoki
doaj +1 more source
The Protective Effects of IL-31RA Deficiency During Bleomycin-Induced Pulmonary Fibrosis
Frontiers in Immunology, 2021 Idiopathic Pulmonary Fibrosis (IPF) is a severe fibrotic lung disease characterized by excessive collagen deposition and progressive decline in lung function.
Dan J. K. Yombo +8 more
doaj +1 more source
IL-31 and IL-33 in rheumatoid arthritis patients
Научно-практическая ревматология, 2022 Objective – to investigate clinical and diagnostic significance of IL-31 and IL-33 determination in patients with rheumatoid arthritis (RA).Material and methods. 154 patients with a reliable diagnosis of RA were examined.
N. A. Lapkina +8 more
doaj +1 more source