Results 41 to 50 of about 56,984,652 (272)

Evaluation of the role of interleukin-31 in inflammatory acne vulgaris: a case–control study

Journal of the Egyptian Women’s Dermatologic Society, 2020
Background Acne vulgaris (AV) is a chronic inflammatory disease with multifactorial etiology and a significant psychological disability. Inflammation is a fundamental process in the early and late stage of acne.
Shahira A Ramadan, Dalia M Abdel Halim, Rofaida El-Naggar, Nahed M Ibrahim, Marwa S El-Mesidy   +4 more
doaj   +1 more source

Interleukin-22 predicts severity and death in advanced liver cirrhosis: a prospective cohort study [PDF]

, 2012
Background: Interleukin-22 (IL-22), recently identified as a crucial parameter of pathology in experimental liver damage, may determine survival in clinical end-stage liver disease.
Stefan Zeuzem, Herrmann, Eva, Oliver Waidmann, Kronenberger, Bernd, Friederike Brunner, Rudloff, Ina, Bernd Kronenberger, Waidmann, Oliver, Albrecht Piiper, Pfeilschifter, Josef (Prof. Dr.), Piiper, Albrecht, Heiko Mühl, Filmann, Natalie, Ina Rudloff, Malte Bachmann, Eva Herrmann, Josef Pfeilschifter, Lisa Kapper, Bachmann, Malte, Brunner, Friederike, Kapper, Lisa, Mühl, Heiko, Natalie Filmann, Zeuzem, Stefan, Kronenberger Bernd, Brunner Friederike, Filmann Natalie, Kapper Lisa, Herrmann Eva, Zeuzem Stefan, Mühl Heiko, Rudloff Ina, Piiper Albrecht, Waidmann Oliver, Bachmann Malte, Pfeilschifter Josef   +35 more
core   +2 more sources

Interleukin-6 levels in the control and AAA groups.

, 2023
There was no significant difference in plasma levels of IL-6 between groups (P = .17). AAA, abdominal aortic aneurysm; IL-6, interleukin-6.
Lenka Maliskova (8781746), Robert L. Raffai (12633072), Shant M. Vartanian (14614693), Adam Z. Oskowitz (14614696), Andrea J. Barczak (782932), Laura Bouchareychas (3493793), Michael S. Conte (12160976), Joshua D. Rudolph (14614690), Phat Duong (5718677), Jose L. Lopez (14614678), Tuan Anh Phu (14614684), Christina R. Kuhrau (14614687), Pei-Yu Lin (3370841), Walter L. Eckalbar (9243670), Joel L. Ramirez (14614681)   +14 more
core   +1 more source

Determination of interleukin 31 (IL-31) serum levels in allergic rhinitis patients

International Journal of Pediatrics & Adolescent Medicine, 2014
Background and objectives: IL-31 appears to be an important regulator of Th2 re-sponses and was found to be present in patients with atopic dermatitis. This study was con-ducted to compare IL-31 serum levels in allergic rhinitis (AR) patients and normal ...
Noor Suryani Mohd Ashari, Siti Noor Syuhada Mohd Amin, Wan Zuraida Wan Abdul Hamid, Mustaffa Musa, Azriani Abdul Rahman, Irfan Mohamad   +5 more
doaj   +1 more source

Interleukin-31: A New Cytokine Involved in Inflammation of the Skin [PDF]

International Journal of Immunopathology and Pharmacology, 2006
Department of Medicine and Science of Aging, University of Chieti, Chieti, Italy; Department of Parasitology, Veterinary School, Aristotelian University, Thessaloniki, Greece; Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine, Boston, U.S.A.; Division of Immunology, Infectious Diseases Otolaryngology Division,
CASTELLANI, Maria Luisa, SALINI, VINCENZO, FRYDAS S, DONELAN J, MADHAPPAN B, PETRARCA, CLAUDIA, VECCHIET, Jacopo, FALASCA, KATIA, NERI, Giampiero, TETE', Stefano   +9 more
openaire   +5 more sources

The role of interleukin-4 receptor alpha on smooth muscle cells during helminth infection [PDF]

, 2011
Includes abstract.Includes bibliographical references (leaves 101-111).Interleukin-4 receptor alpha (IL-4Ra) signaling, mediated by the ligands IL-4 and IL- 13, is important for effective host protection during murine Nippostrongylus brasiliensis (N ...
Brombacher, Tiroyaone M H
core   +1 more source

Profile of Serum Interleukin-31 Levels in Atopic Dermatitis

Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology), 2017
Background: Atopic dermatitis (AD) is a chronic inflammatory skin disorder characterized by pruritic skin lesion. Pathogenesis of AD is not fully understood, but recent studies demonstrate the role of interleukin-31 (IL-31).
Dewi Kusumawati, Cita Rosita Prakoeswa, Rahmadewi Rahmadewi   +2 more
doaj   +1 more source

The antiangiogenic role of the pro-inflammatory cytokine interleukin-31. [PDF]

Oncotarget, 2017
Pro-inflammatory cytokines in the tumor microenvironment are known for their ability to either inhibit or promote cancer progression. Here we evaluated the role of Interleukin-31 (IL31), a protein belonging to the pro-inflammatory IL-6 cytokine family which has been characterized in autoimmune disease, in tumorigenesis.
Davidi S, Fremder E, Kan T, Raviv Z, Timaner M, Karin N, Hershkovitz D, Arohneim A, Shaked Y.   +8 more
europepmc   +4 more sources

Efficacy and safety of vixarelimab, a human monoclonal oncostatin M receptor β antibody, in moderate-to-severe prurigo nodularis: a randomised, double-blind, placebo-controlled, phase 2a studyResearch in context

EClinicalMedicine, 2023
Summary: Background: Prurigo nodularis is a chronic skin disease characterised by intensely pruritic, hyperkeratotic nodules. Vixarelimab, a human monoclonal antibody, binds to the beta subunit of the oncostatin M receptor, inhibiting signalling of both
Howard Sofen, Robert Bissonnette, Gil Yosipovitch, Jonathan I. Silverberg, Stephen Tyring, Wei Jing Loo, Matthew Zook, Mark Lee, Liangxing Zou, Guang-Liang Jiang, John F. Paolini   +10 more
doaj   +1 more source

Increased levels of interleukin 31 (IL-31) in osteoporosis. [PDF]

BMC Immunol, 2015
Several inflammatory cytokines play a key part in the induction of osteoporosis. Until now, involvement of the Th2 cytokine interleukin-31 (IL-31) in osteoporosis hadn't yet been studied. IL-31 is a proinflammatory cytokine mediating multiple immune functions, whose involvement in a wide range of diseases, such as atopic dermatitis, inflammatory bowel ...
Ginaldi L, De Martinis M, Ciccarelli F, Saitta S, Imbesi S, Mannucci C, Gangemi S.   +6 more
europepmc   +6 more sources