Results 11 to 20 of about 669,728 (307)

Th2 cytokines and asthma — The role of interleukin-5 in allergic eosinophilic disease [PDF]

Respiratory Research, 2001
Interleukin-5 is produced by a number of cell types, and is responsible for the maturation and release of eosinophils in the bone marrow. In humans, interleukin-5 is a very selective cytokine as a result of the restricted expression of the interleukin-5 ...
Chapman Richard W, Cuss Francis M, Umland Shelby P, Greenfeder Scott, Egan Robert W   +4 more
doaj   +3 more sources

Cooperation between interleukin-5 and the chemokine eotaxin to induce eosinophil accumulation in vivo. [PDF]

, 1995
Experiments were designed to study the effect of systemically administered IL-5 on local eosinophil accumulation induced by the intradermal injection of the chemokine eotaxin in the guinea pig.
Collins, PD, Griffiths-Johnson, DA, Jose, PJ, Marleau, S, Williams, TJ   +4 more
core   +2 more sources

Autoimmune hepatitis with eosinophilic infiltration responsive to anti-interleukin-5 receptor treatment: a case report and literature review

Italian Journal of Medicine, 2023
Inflammatory tissue damage plays a role in the onset, progression, and exacerbation of various chronic autoimmune and metabolic diseases such as autoimmune hepatitis. Here we present a case of autoimmune hepatitis with liver eosinophilic infiltrate in a
Francesca Romana Ponziani, Cristiano Caruso, Ilaria Baglivo, Francesco Macagno, Antonio Gasbarrini, Francesco Santopaolo, Maria Cristina Giustiniani, Stefania Colantuono, Maurizio Pompili   +8 more
doaj   +1 more source

INTERLEUKIN-5 IS A NEW TARGET IN THE TREATMENT OF EOSINOPHILIC GRANULOMATOSIS WITH POLYANGIITIS

Научно-практическая ревматология, 2020
Interleukin-5 (IL-5) is involved in the maturation and activation of eosinophils, its production is increased in patients with eosinophilic granulomatosis with polyangiitis (EGPA).
T. V. Beketova, E. V. Arseniev
doaj   +1 more source

Heterogeneity of Group 2 Innate Lymphoid Cells Defines Their Pleiotropic Roles in Cancer, Obesity, and Cardiovascular Diseases

Frontiers in Immunology, 2022
Group 2 innate lymphoid cells (ILC2s) are typically known for their ability to respond rapidly to parasitic infections and play a pivotal role in the development of certain allergic disorders.
Masashi Ikutani, Susumu Nakae, Susumu Nakae   +2 more
doaj   +1 more source

B-1 Cell Heterogeneity and the Regulation of Natural and Antigen-Induced IgM Production. [PDF]

, 2016
A small subset of B cells, termed B-1 cells, with developmental origins, phenotypes, and functions that are distinct from those of conventional B cells exist in mice. It contributes the vast majority of spontaneously produced "natural" IgM.
Alugupalli, Alugupalli, Ansel, Avrech, Barber, Baumgarth, Baumgarth, Baumgarth, Baumgarth, Ben-Hur, Berland, Boes, Boes, Briles, Cazac, Chace, Chen, Choi, Choi, Cole, Colombo, Cosenza, Cunningham, Dexter, Duber, Ehrenstein, Elvington, Flajnik, Forster, Fung, Gil-Cruz, Godin, Gordon, Ha, Haas, Hardy, Hardy, Hayakawa, Hayakawa, Holodick, Holodick, Holodick, Hooijkaas, Kantor, Kantor, Kawahara, Kearney, Kin, Kobayashi, Kretschmer, Kroese, Kroese, Lalor, Lalor, Lalor, Mercolino, Montecino-Rodriguez, Montecino-Rodriguez, Moon, Morris, Murakami, Nguyen, Nisitani, Ohdan, Okabe, Ouchida, Patel, Perdiguero, Rahyab, Reynolds, Sigal, Stoermann, Tominaga, Tornberg, van der Pol, Vas, Vaux, Waffarn, Wardemann, Watanabe, Yang, Yang, Yoshida, Yoshimoto, Yuan, Zhou   +85 more
core   +5 more sources

Cytokine profile associated with human chronic schistosomiasis mansoni

Memorias do Instituto Oswaldo Cruz, 2004
This study objective was to evaluate the cytokines associated with early events of hepatic fibrosis in schistosomiasis mansoni. Hepatic fibrosis was classified by ultrasonography in 94 patients.
Andréa Magalhães, Delfin Gonzalez Miranda, Roberval Gonzalez Miranda, Maria Ilma Araújo, Adriana Almeida de Jesus, Angela Silva, Luciana B Santana, Edward Pearce, Edgar M Carvalho, Amélia Ribeiro de Jesus   +9 more
doaj   +1 more source

Association between the interleukin-5 receptor alpha-subunit G-80A polymorphism and immunological parameters in asthmatic children

Biomedical and Biotechnology Research Journal, 2020
Introduction: The expression of human interleukin-5 (IL-5) receptor alpha (Rα)-subunit presented on eosinophils, mast cells, and basophils. Hence, a polymorphism in IL-5 Rα may be implicated in the development of asthma and effect on immunological ...
Raghdah Maytham Hameed, Haidar Abdul Amir Najim Abood, Mohanad Mohsin Ahmed   +2 more
doaj   +1 more source

Staphylococcus aureus controls interleukin-5 release in upper airway inflammation [PDF]

, 2018
Staphylococcus aureus is a frequent colonizer of the upper airways in chronic rhinosinusitis with nasal polyps, but also resides intramucosally, it has been shown that secreted staphylococcal proteins such as enterotoxins and serine proteases induce the ...
Bachert, Claus, Bröker, BM, Gevaert, Elien, Holtappels, Gabriële, Merabishvili, Maia, Meyer, T, Murr, A, Schmidt, F, Van Crombruggen, Koen, Vaneechoutte, Mario, Völker, U, Zhang, Nan   +11 more
core   +2 more sources

Interleukin-5 modulates interleukin-8 secretion in eosinophilic inflammation

Mediators of Inflammation, 1998
Serum and BALF (bronchoalveolar lavage fluid) IL-8 levels and serum levels were investigated in Tox ocara canis infected guinea-pigs and the role of IL-5 as a modulator of cytokine secretion was studied.
L. H. Faccioli, A. I. Medeiros, A. Malheiro, R. C. L. R. Pietro, A. Januário, B. B. Vargaftig   +5 more
doaj   +1 more source