Results 21 to 30 of about 657,596 (286)

Interleukin-5 modulates interleukin-8 secretion in eosinophilic inflammation

Mediators of Inflammation, 1998
Serum and BALF (bronchoalveolar lavage fluid) IL-8 levels and serum levels were investigated in Tox ocara canis infected guinea-pigs and the role of IL-5 as a modulator of cytokine secretion was studied.
L. H. Faccioli, A. I. Medeiros, A. Malheiro, R. C. L. R. Pietro, A. Januário, B. B. Vargaftig   +5 more
doaj   +1 more source

Association between the interleukin-5 receptor alpha-subunit G-80A polymorphism and immunological parameters in asthmatic children

Biomedical and Biotechnology Research Journal, 2020
Introduction: The expression of human interleukin-5 (IL-5) receptor alpha (Rα)-subunit presented on eosinophils, mast cells, and basophils. Hence, a polymorphism in IL-5 Rα may be implicated in the development of asthma and effect on immunological ...
Raghdah Maytham Hameed, Haidar Abdul Amir Najim Abood, Mohanad Mohsin Ahmed   +2 more
doaj   +1 more source

Antagonism of cytokine-induced eosinophil accumulation in asthma [PDF]

, 2012
Peer reviewedPublisher ...
Walsh, Garry M.
core   +2 more sources

Eosinophilia Associated With CD3−CD4+ T Cells: Characterization and Outcome of a Single-Center Cohort of 26 Patients

Frontiers in Immunology, 2020
Background: Lymphocytic variant hypereosinophilic syndrome is characterized by marked over-production of eosinophilopoietic factor(s) by dysregulated T cells leading to eosinophil expansion.
Caroline Carpentier, Sylvain Verbanck, Liliane Schandené, Pierre Heimann, Anne-Laure Trépant, Elie Cogan, Florence Roufosse, Florence Roufosse   +7 more
doaj   +1 more source

The course and outcomes of COVID-19 in patients with ANCA-associated systemic vasculitis, receiving biological therapy (Rituximab, Mepolizumab): The results of the first 8 months of the pandemic

Научно-практическая ревматология, 2021
Objective. Currently, the issues of the effect of anti-B cell therapy or inhibitor of interleukin 5 on the risk of COVID-19 infecting and outcomes in patients with ANCA-associated vasculitis (AAV) has not been completely studied.
T. V. Beketova, V. V. Babak, M. D. Suprun   +2 more
doaj   +1 more source

We Have to Learn to Do Without Knowing Enough: Anti-Eosinophilic Treatments for Severe Asthma [PDF]

, 2018
Interleukin.5 (IL.5) is the main eosinophilic cytokine that promotes the differentiation, survival, and activation of eosinophils, which are the key inflammatory cells in severe eosinophilic asthma .Thus, it is no surprise that ...
4,, BEGHE', Bianca, Fabbri, Lm3, Papi, A1   +3 more
core   +1 more source

IL-5 and IL-5 receptor in asthma

Memorias do Instituto Oswaldo Cruz, 1997
Eosinophils, along with mast cells are key cells involved in the innate immune response against parasitic infection whereas the adaptive immune response is largely dependent on lymphocytes. In chronic parasitic disease and in chronic allergic disease, IL-
Kotsimbos ATC, Hamid Q
doaj   +3 more sources

Recovery of smell sense loss by mepolizumab in a patient allergic to dermatophagoides and affected by chronic rhinosinusitis with nasal polyps [PDF]

, 2019
Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) frequently presents with dysfunction or loss of the sense of smell, resulting in a signifcant impairment in quality of life.
Cavaliere, Carlo, Ciotti, Mario, de Vincentiis, Marco, Frati, Franco, Greco, Antonio, Incorvaia, Cristoforo, Masieri, Simonetta, Messineo, Daniela   +7 more
core   +1 more source

Interleukin-5 and Interleukin-5 Receptor Polymorphism in Asthma

, 2023
Asthma is a common chronic inflammatory disease of the airways of the lungs, in the world. It’s associated with type 2 cytokines interleukin-4, IL-5, and IL-13, which promote airway eosinophilia, bronchial hyperresponsiveness, mucus overproduction, and immunogloubulin E synthesis.
Maytham, Hameed, Raghdah, Najim, Abood, Haidar Abdul Amir, Mohsin, Ahmed, Mohanad   +2 more
openaire   +2 more sources

Role of a Th2 cytokine inhibitor in asthma treatment

Allergology International, 2004
The airway wall of asthmatic patients is infiltrated with inflammatory cells, consisting chiefly of eosinophils and T lymphocytes. Among these T lymphocytes, Th2 cells are involved in the regulation of the IgE immune response and local allergic ...
Jun Tamaoki
doaj   +1 more source