Results 221 to 230 of about 848,154 (350)
Legumain (LGMN) is upregulated in macrophages during sarcoid‑like granuloma formation. Macrophage‑derived LGMN binds to integrin αvβ3 and suppresses mTORC1/STAT1 signaling to restrain M1 macrophage polarization. Intratracheal delivery of lipid nanoparticles carrying Lgmn plasmid DNA (pDNA) elevates LGMN expression and effectively attenuates pulmonary ...
Mengyuan Liu +12 more
wiley +1 more source
Interleukin-22 functions to alleviate hypoxia-induced intestinal inflammation by modulating pro- and anti-inflammatory factors in <i>Pelteobagrus fulvidraco</i>. [PDF]
Huan HQ +6 more
europepmc +1 more source
Interleukin-22 regulates neutrophil recruitment in ulcerative colitis and is associated with resistance to ustekinumab therapy. [PDF]
Pavlidis P +24 more
europepmc +1 more source
ABSTRACT Intestinal ischemia/reperfusion (I/R) injury presents a biphasic pathology: an acute oxidative‐inflammatory phase leading to organ failure, and a recovery phase marked by mucosal dysfunction and bacterial translocation. The developed MPB@TA‐Cu‐Ma nanocomposite functions as a dual‐phase therapeutic platform with significant efficacy. It rapidly
Chenghao Qiu +15 more
wiley +1 more source
Cytokines and Madness: A Unifying Hypothesis of Schizophrenia Involving Interleukin-22. [PDF]
Sfera A, Thomas KA, Anton J.
europepmc +1 more source
Correction: Interleukin-22-deficiency and microbiota contribute to the exacerbation of Toxoplasma gondii-induced intestinal inflammation [PDF]
A Couturier-Maillard +17 more
openalex +1 more source
Leveraging Macrophage Metabolic Reprogramming for Enhanced Anti‐Tumor Immunity
Tumor‐associated macrophages (TAMs) are key regulators of the tumor microenvironment (TME), with their metabolic states playing a critical role in tumor progression or regression. This review summarizes current understanding of TAM metabolic plasticity alongside cutting‐edge bioengineering innovations, outlining a roadmap for transforming the ...
Zhiyun Liu +8 more
wiley +1 more source

