Lymphoid‐Tissue‐on‐Chip Recapitulates Human Antibody Responses In Vitro
The presented lymphoid‐tissue‐on‐chip system allows culture of primary human tonsil cells at organotypic high density under perfusion for up to 4 weeks, emulates immune response to soluble vaccines and vaccination via peripheral antigen‐presenting cells and represents a useful tool to assess cellular interactions during homeostasis, immune responses ...
Claudia Teufel +15 more
wiley +1 more source
Interleukin-22 in Renal Protection and Its Pathological Role in Kidney Diseases. [PDF]
Ma Q +7 more
europepmc +1 more source
Liquid Metal Nanotransformers for Drug‐Resistant Pan‐Cancer Therapy in Patient‐Derived Organoids
Pan‐cancer therapies are severely limited in drug‐resistance patients due to genetic mutations and other factors, resulting in poor therapeutic outcomes and constrained clinical benefit. Liquid metal nanotransformers, a new class of shape‐transformable nanomaterials capable of dramatic morphological changes, offer a promising physical strategy to ...
Xiaojie Yuan +19 more
wiley +1 more source
Cytokines and chemokines in Mycobacterium tuberculosis infection [PDF]
Cooper, Andrea +3 more
core +2 more sources
Interleukin-22 promotes cancer stemness and chemotherapy resistance in colorectal cancer <i>via</i> epidermal growth factor receptor/extracellular signal-regulated kinase pathway. [PDF]
Ruan HX, Fang YL, Qin XN, Lin L.
europepmc +1 more source
Interleukin-22 and interleukin-33 show up-regulated levels in the serum of patients with mild/moderate Coronavirus disease 2019. [PDF]
Majeed AY, Zulkafli NES, Ad'hiah AH.
europepmc +1 more source
Interleukin 22 mitigates endothelial glycocalyx shedding after lipopolysaccharide injury
Sharven Taghavi +5 more
openalex +2 more sources
Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4‐Mediated Acute Hepatitis
This study identifies hepatocyte‐derived BDNF as an endogenous TLR4 antagonist that alleviates acute hepatitis. BDNF is downregulated in hepatocytes via REST‐mediated transcriptional repression during ALI/ALF. Mechanistically, BDNF binds to TLR4 on macrophages to suppress inflammation.
Weiwei Zhu +15 more
wiley +1 more source

