Results 61 to 70 of about 60,800,054 (257)

Dislipidemia and Serum Level of Interleukin-22 in Hyptrtensive Patients with Concomitant Excessive Body Weight or Obesity

open access: yes, 2017
Introduction. Hypertension is the most common chronic disease that has up to 20.0-30.0 % of the adult population of the planet. The presence of concomitant diseases, including obesity worsens the course and prognosis of Hypertension.
Kovalyova O.   +2 more
core   +1 more source

The role of interleukin-4 receptor alpha on smooth muscle cells during helminth infection [PDF]

open access: yes, 2011
Includes abstract.Includes bibliographical references (leaves 101-111).Interleukin-4 receptor alpha (IL-4Ra) signaling, mediated by the ligands IL-4 and IL- 13, is important for effective host protection during murine Nippostrongylus brasiliensis (N ...
Brombacher, Tiroyaone M H
core   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

The effects of anti-interleukin-5 on SABA rescue use.

open access: yes, 2016
The effects of anti-interleukin-5 on SABA rescue use.
Ting Liu (45625)   +4 more
core   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

Role of Interleukin-22 in Tumor Angiogenesis [PDF]

open access: yes, 2017
There is increasing recognition that the immune system plays a crucial role in either the promotion or inhibition of tumor development and growth. Current models of tumorigenesis rely on cells’ ability to evade the immune system. Escaping immune-mediated
Protopsaltis, Nicholas James
core  

Interleukin‑17A and Interleukin‑18 level in the blood serum of patients with different clinical course of Rosacea [PDF]

open access: yes, 2018
Introduction. Rosacea is a common chronic dermatosis characterized by lesions of open areas of the skin (face) and torpidity to treatment. The objective of our study was to determine and analyze the content of proinflammatory cytokines – interleukin‑17A
Olha I. DENYSENKO, Maryna V. STOROZHUK
core   +2 more sources

Interleukin 22 disrupts pancreatic function in newborn mice expressing IL-23

open access: yesNature Communications, 2019
Necrotizing enterocolitis (NEC) is associated with severe neonatal morbidity. Here the authors show, mirroring the NEC phenotype, that IL-23 overexpression in neonates causes malabsorption and decreased expression of intestinal and pancreatic genes ...
Lili Chen   +13 more
doaj   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

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