Results 141 to 150 of about 63,478,598 (186)

536 Analysis of serum interleukin-10 and interleukin-35 levels In pemphigoid patients [PDF]

Journal of Investigative Dermatology, 2018
M. Kabuto, N. Fujimoto, T. Takahashi, T. Tanaka   +3 more
openaire   +1 more source

Interleukin-35 promotes progression of prostate cancer and inhibits anti-tumour immunity. [PDF]

Cancer Cell Int, 2020
Zhu J, Wang Y, Li D, Zhang H, Guo Z, Yang X.   +5 more
europepmc   +1 more source

Vitreous levels of interleukin-35 as a prognostic factor in B-cell vitreoretinal lymphoma. [PDF]

Sci Rep, 2020
Takeda A, Hasegawa E, Nakao S, Ishikawa K, Murakami Y, Hisatomi T, Arima M, Yawata N, Oda Y, Kimura K, Yoshikawa H, Sonoda KH.   +11 more
europepmc   +1 more source

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Interleukin-35 in idiopathic inflammatory myopathies

Cytokine, 2021
Interleukin-35 (IL-35) is a recently described heterodimeric cytokine that belongs to the IL-12 family and consists of p35 (IL-12a) and EBI3 (IL-27b) subunits. The expression of IL-35 in humans is inducible in response to inflammatory stimuli. Increased IL-35 levels were documented in several autoimmune inflammatory diseases, suggesting a possible ...
Heřman Mann, Olga Kryštůfková, Josef Zámečník, Jaromír Háček, Hana Hulejová, Mária Filková, Jiří Vencovský, Ladislav Šenolt   +7 more
openaire   +2 more sources

The Mechanism of Interleukin-35 in Chronic Hepatitis B

Seminars in Liver Disease, 2021
AbstractInterleukin-35 (IL-35) is a newly identified inhibitory cytokine. It has recently been found to play an extremely important role in chronic hepatitis B disease, which makes it likely to be a target for new therapies for hepatitis B malady. IL-35 modulates a variety of immune mechanisms to cause persistent viral infections, such as affecting the
Ying, Tang, Tianyi, Ma, Shengnan, Jia, Qian, Zhang, Siqi, Liu, Ling, Qi, Lanlan, Yang   +6 more
openaire   +2 more sources

The role of interleukin 35 in atherosclerosis

Current Pharmaceutical Design, 2015
Atherosclerosis has been widely recognized as a slow progressing inflammatory disease of the arterial walls involving both inflammation and autoimmune processes with a complex etiology in which the immune system plays a key role. A hallmark of atherosclerosis is that the macrophages pick up the lipids to form the foam cells which build up the plaque in
Juntang, Lin, Vijay, Kakkar, Xinjie, Lu
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Role of interleukin‐35 in cardiovascular diseases

Scandinavian Journal of Immunology, 2022
AbstractCardiovascular disease represents a complex series of clinical syndromes with multiple aetiologies. Cardiovascular diseases have become one of the most common causes of death among middle‐aged and elderly people worldwide because of their diverse types and wide range of patients.
Jialun Zhang, Yue Xing
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Interleukin-35 takes the 'B' line

Nature Medicine, 2014
Regulatory B cells exert an immunosuppressive role by secreting the cytokine interleukin-10 (IL-10). Two studies have now identified B cell–derived IL-35 as both an inducer and a mediator of regulatory B cell function. IL-35 switched off inflammation in mouse models of autoimmunity, whereas its absence in B cells in mice enhanced survival after ...
Claudia, Mauri, Kiran, Nistala
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The immunomodulatory role of interleukin-35 in fibrotic diseases

Expert Review of Clinical Immunology, 2019
Fibrosis makes numerous diseases in all organs more complicated and leads to severe consequences in the lung, liver, heart, kidney, and skin. In essence, fibrosis results from excessive, persistent and oftentimes nonreversible aggregation of extracellular matrix (ECM) or simply as collagen during the process of tissue injury and repair.
Man, Luo, Hong, Peng, Ping, Chen, Yong, Zhou   +3 more
openaire   +2 more sources