Results 41 to 50 of about 63,478,598 (186)
Molecular Pathways: Interleukin-35 in Autoimmunity and Cancer [PDF]
Clinical Cancer Research, 2016 Abstract Immunosuppressive functions conferred by regulatory cytokines are important for maintaining homeostasis in immune responses. IL35 has recently emerged as a novel regulator of immune responses. Once thought to be specifically expressed by T regulatory cells, induction of IL35 expression has now been detected in multiple cell ...
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Interleukin (IL)-35 is raising our expectations [PDF]
Revista médica de Chile, 2010 To elucidate and discuss the role of IL-35 in immunity to parasitic and bacterial infections as well as in autoimmunity in terms of its anti-inflammatory properties, we highlight significant findings on this novel member of the IL-12 family.Studies using genetically deficient mice have greatly enhanced our understanding of the biology of IL-35.
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cDNA Cloning of Biologically Active Chicken Interleukin-18 [PDF]
, 2000 By searching a chicken EST database, we identified a cDNA clone that appeared to contain the entire open reading frame (ORF) of chicken interleukin-18 (ChIL-18).
Stäheli, Peter +15 more
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Cyprus Journal of Medical SciencesBACKGROUND/AIMS: Human immunodeficiency virus (HIV) infection remains a worldwide public health challenge, primarily due to its disruption of immune regulation and cytokine homeostasis.
Mine Büşra Bozkürk +6 more
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Mathematical modeling of Interleukin-35 promoting tumor growth and angiogenesis.
, 2014 Interleukin-35 (IL-35), a cytokine from the Interleukin-12 cytokine family, has been considered as an anti-inflammatory cytokine which promotes tumor progression and tumor immune evasion. It has also been demonstrated that IL-35 is secreted by regulatory
Kang-Ling Liao, Xue-Feng Bai, and Avner Friedman +6 more
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Interleukin‐35: odd one out or part of the family? [PDF]
Immunological Reviews, 2008 Summary: Advances in cytokine biology have helped us understand the complex communication that takes place between antigen‐presenting cells and cells of the adaptive immune system, such as T cells, which collectively mediate an appropriate immune response to a plethora of pathogens while maintaining tolerance to
Lauren W, Collison, Dario A A, Vignali
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Iranian Journal of Allergy, Asthma and Immunology, 2022 Schizophrenia (SCZ) is a debilitating mental disorder with various causes involving complex interactions between genetic factors and environmental agents.
Marziyeh Soltani +8 more
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Mathematical modeling of interleukin-27 induction of anti-tumor T cells response. [PDF]
, 2014 Interleukin-12 is a pro-inflammatory cytokine which promotes Th1 and cytotoxic T lymphocyte activities, such as Interferon-[Formula: see text] secretion. For this reason Interleukin-12 could be a powerful therapeutic agent for cancer treatment.
Kang-Ling Liao, Xue-Feng Bai, and Avner Friedman +9 more
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Interleukin‐35 in immune‐related diseases: protection or destruction [PDF]
Immunology, 2019 SummaryInterleukin‐35 (IL‐35) is a recently identified heterodimeric cytokine in the IL‐12 family. It consists of an IL‐12 subunit α chain (P35) and IL‐27 subunit Epstein–Barr virus‐induced gene 3 (EBI3) β chain. Unlike the other IL‐12 family members, it signals through four unconventional receptors: IL‐12Rβ2–IL‐27Rα, IL‐12Rβ2–IL‐12Rβ2, IL‐12Rβ2–GP130,
Junfeng Zhang +6 more
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Advances in Rheumatology, 2022 Background Systemic lupus erythematosus (SLE) is a systemic autoimmune disease that associates with aberrant activation of B lymphocytes and excessive autoantibodies.
Hui Xiong +8 more
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