Results 51 to 60 of about 63,478,598 (186)

Interleukin‑35 is associated with the tumorigenesis and progression of prostate cancer

open access: yesOncology Letters, 2019
Interleukin (IL)-35 is a novel member of the IL-12 cytokine family, which exhibits a unique immune regulatory function. Previously, it was demonstrated that IL-35 expression is significantly increased in a wide range of tumor tissues, promoting angiogenesis and inhibiting the anti-tumor immune response.
Zhu, Jialin   +4 more
openaire   +3 more sources

Interleukin-35 Is Involved in Angiogenesis/Bone Remodeling Coupling Through T Helper 17/Interleukin-17 Axis

open access: yesFrontiers in Endocrinology, 2021
ObjectiveOsteoporosis is a common metabolic bone disease mainly involving bone remodeling and blood vessels. The current study aimed to explore the suppressive role of interleukin (IL)-35 in nuclear factor kappa-B ligand receptor activator (RANKL) and ...
Hui Zhang   +7 more
doaj   +1 more source

Interleukin-35 Suppresses Interleukin-9-Secreting CD4+ T Cell Activity in Patients With Hepatitis B-Related Hepatocellular Carcinoma

open access: yesFrontiers in Immunology, 2021
Chronic hepatitis B virus (HBV) infection induces dysfunction of immune response and chronic liver damage. However, the mechanisms that account for HBV-related hepatocellular carcinoma (HCC) are poorly understood.
Qian Zhang   +4 more
doaj   +1 more source

The effects of anti-interleukin-5 on SABA rescue use.

open access: yes, 2016
The effects of anti-interleukin-5 on SABA rescue use.
Ting Liu (45625)   +4 more
core   +1 more source

Truncated Chicken Interleukin-1β with Increased Biologic Activity [PDF]

open access: yes, 2003
Chicken interleukin-1β (ChIL-1β) is synthesized as a precursor molecule that unlike its mammalian counterpart, lacks a typical caspase-1 cleavage site. Therefore, it was unclear if proteolytic cleavage of ChIL-1β can occur and if cleavage might modulate ...
Erno Duda   +10 more
core   +1 more source

Rapid Communication: Plasma Interleukin-35 in Children with Autism [PDF]

open access: yesBrain Sciences, 2019
In autism spectrum disorders (ASD) many individuals have co-morbid immune dysregulation that can lead to inflammation in the brain and periphery. The novel cytokine interleukin (IL)-35 has described anti-inflammatory properties; however, the plasma levels of IL-35 in children with ASD have never been investigated.
Rose, Destanie, Ashwood, Paul
openaire   +5 more sources

Interleukin-35 on B cell and T cell induction and regulation

open access: yesJournal of Inflammation, 2017
Interleukin (IL)-35 is a relatively newly discovered member of IL-12 cytokine family that is unique in that it is a dimer formed by two subunits. The review documents the structure, secretion and signal transduction of IL-35, the regulation effect of IL ...
Ai Huang   +5 more
doaj   +1 more source

Interleukin‑17A and Interleukin‑18 level in the blood serum of patients with different clinical course of Rosacea [PDF]

open access: yes, 2018
Introduction. Rosacea is a common chronic dermatosis characterized by lesions of open areas of the skin (face) and torpidity to treatment. The objective of our study was to determine and analyze the content of proinflammatory cytokines – interleukin‑17A
Olha I. DENYSENKO, Maryna V. STOROZHUK
core   +2 more sources

The role of interleukin-4 receptor alpha on smooth muscle cells during helminth infection [PDF]

open access: yes, 2011
Includes abstract.Includes bibliographical references (leaves 101-111).Interleukin-4 receptor alpha (IL-4Ra) signaling, mediated by the ligands IL-4 and IL- 13, is important for effective host protection during murine Nippostrongylus brasiliensis (N ...
Brombacher, Tiroyaone M H
core   +1 more source

Heterogeneity in the granulomatous response to mycobacterial infection in patients with defined genetic mutations in the interleukin 12-dependent interferon-gamma production pathway

open access: yes, 2002
Granulomatous Diseases Review Heterogeneity in the granulomatous response to mycobacterial infection in patients with defined genetic mutations in the interleukin 12-dependent interferon-gamma production ...
Kumararatne, D.S.   +49 more
core   +1 more source

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