Results 71 to 80 of about 63,478,598 (186)

A comprehensive analysis of interleukin-4 receptor polymorphisms and their association with atopy and IgE regulation in childhood [PDF]

, 2004
Background: The interleukin (IL) 4/IL13 pathway is involved in the regulation of IgE production associated with atopic diseases. Numerous polymorphisms have been identified in the coding region of the IL4 receptor alpha chain (IL4Ra) and previous ...
Kabesch, Michael, Stachel, Daniel, Carr, David, Schmid, Irene, Woitsch, Bernd, Weiland, Stephan K., Fritzsch, Christian, Mutius, Erika von   +7 more
core   +1 more source

Interleukin-35 expression is associated with colon cancer progression

Oncotarget, 2017
Colon cancer development is closely related to inflammation. Thus, we conducted the present investigation to study the effects of IL-35 (Interleukin 35), a newly identified anti-inflammatory factor, on colon cancer development. We first evaluated the IL-35 expression in 186 pairs of colon cancer samples and paired adjacent normal tissues by qPCR, ELISA
Zhang, Jian, Mao, Tao, Wang, Shuyun, Wang, Dongsheng, Niu, Zhaojian, Sun, Zhenqing, Zhang, Jianli   +6 more
openaire   +3 more sources

Assessment of the Interleukin-32 and Interleukin-35 Levels in the Circulation of Hashimoto’s Thyroiditis Patients

Medical Journal of Babylon
Background: Hashimoto’s thyroiditis (HT) is a more common autoimmune disease causing chronic thyroid gland inflammation with many genetic and environmental uncertain etiologies. The main characteristic of HT is the loss of thyroid tissue as a result of a
Ahmed Hadi Saeed Al-Khafaji, Jawad Kadhim Tarrad Al-Khafaj, Abdulnabi J. Abid   +2 more
doaj   +1 more source

Interleukin-10, polymorphism in SLC11A1 (formerly NRAMP1), and susceptibility to tuberculosis.

, 2002
Host genetic factors are major determinants of susceptibility to tuberculosis, and an understanding of the molecular basis of this observation has major implications for the development of novel therapies and vaccines.
Howson, Joanna M M, Awomoyi, Agnes A, Agnes A Awomoyi (16176401), Arnaud Marchant (70401), Joanna M M Howson (3809950), Newport, M J, Keith P W J McAdam (16181906), Melanie Newport (4461202), McAdam, K P, Marchant, Arnaud, Blackwell, Jenefer M, Jenefer M Blackwell (10682454)   +11 more
core   +1 more source

Immunoreactivity for interleukin-33 in allergic airway inflammation [PDF]

, 2015
Immunoreactivity for Interleukin-33 in Allergic Airway Inflammation,Cristan Herbert, Melissa M. Bunting, Neil Lambie, Paul S.
Kumar, RK ; https://orcid.org/, Herbert, C ; https://orcid.org/, Bunting, MM, Lambie, N, Thomas, PS ; https://orcid.org/   +4 more
core   +1 more source

Interleukin-4 serum concentrations of dogs fed control or supplemented diet with beta-glucan.

, 2018
Values determined before vaccination (time 0), seven days after the first dose of vaccine (time 7) and 21 days after the first dose of vaccine (time 21). IL-4: interleukin-4.
Karen Guttenkunst Lisenko (5575100), Lívia Geraldi Ferreira (5575094), Márcio Gilberto Zangeronimo (4771806), Flávia Maria de Oliveira Borges Saad (5575118), Ana Paula Peconick (5575115), Mariangela Endrighi (5575097), Maiara Rodrigues Duarte de Oliveira (5575103), Pamella Godinho Gutierres (5575112), Mateus Resende Damasceno (5575106), Jelieny Aparecida Claudino (5575109)   +9 more
core   +1 more source

Interleukin-10/Interleukin-5 responses at birth predict risk for respiratory infections in children with atopic family history

, 2009
Interleukin-10/Interleukin-5 responses at birth predict risk for respiratory infections in children with atopic family ...
M Kusel (10012535), PG Holt (14457411), A Bosco (13307889), K McKenna (9886307), G Zhang (7349387), PD Sly (14453628), J Rowe (9877307), N De Klerk (13369254)   +7 more
core  

Interleukin-35 Inhibits TNF-α-Induced Osteoclastogenesis and Promotes Apoptosis via Shifting the Activation From TNF Receptor-Associated Death Domain (TRADD)–TRAF2 to TRADD–Fas-Associated Death Domain by JAK1/STAT1

Frontiers in Immunology, 2018
Over-activated osteoclasts derived from myeloid or peripheral blood monocytes by inflammatory cytokines results in osteoporosis, osteoarthritis, and other bone erosion-related diseases.
Mingzheng Peng, Yanguo Wang, Lei Qiang, Lei Qiang, Yan Xu, Yan Xu, Cuidi Li, Tao Li, Xiaojun Zhou, Ming Xiao, Jinwu Wang   +10 more
doaj   +1 more source

Genetic partitioning of interleukin-6 signalling in mice dissociates Stat3 from Smad3-mediated lung fibrosis [PDF]

, 2012
Idiopathic pulmonary fibrosis (IPF) is a fatal disease that is unresponsive to current therapies and characterized by excessive collagen deposition and subsequent fibrosis.
Bozinovski, S, O'Donoghue, R.J.J., Prêle, C.M., Ernst, M.R., Anderson, GP, Vlahos, R., Knight, DA, McKenzie, B.S., Wang, B, Jarnicki, AG, Prêle, CM, Laurent, GJ, McAnulty, R.J., Thiem, S, Lau, HL, Vlahos, R, Zhu, H.J., Richards, CD, Mutsaers, SE, Ernst, MR, Stumbles, P.A., Laurent, G.J., Knight, D.A., Thiem, S., Jarnicki, A.G., Lau, H.L., O'Donoghue, RJJ, McAnulty, RJ, Stumbles, P, Richards, C.D., Anderson, G.P., McKenzie, BS, Rose-John, S, Mutsaers, S.E., Zhu, HJ, Wang, B., Jones, J., Rose-John, S., Jones, J, Bozinovski, S.   +39 more
core   +1 more source

Decreased Circulating Interleukin-35 Levels Are Related to Interleukin-4-Producing CD8+ T Cells in Patients with Allergic Asthma

Iranian Journal of Allergy, Asthma and Immunology, 2015
Interleukin (IL)-35 is a newly discovered suppressive cytokine and has been shown to alleviate  inflammatory  and  autoimmune  diseases.  The  purpose  of  this  study  was  to investigate immunomodulatory capacity of IL-35 in patients with allergic ...
Wei Wang, Ping Li, Jiong Yang
doaj