Role of Intermediate Filaments in Blood–Brain Barrier in Health and Disease [PDF]
Cells, 2021 The blood–brain barrier (BBB) is a highly selective cellular monolayer unique to the microvasculature of the central nervous system (CNS), and it mediates the communication of the CNS with the rest of the body by regulating the passage of molecules into ...
Ece Bayir, Aylin Sendemir
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Pathophysiological Role of Vimentin Intermediate Filaments in Lung Diseases [PDF]
Frontiers in Cell and Developmental Biology, 2022 Vimentin intermediate filaments, a type III intermediate filament, are among the most widely studied IFs and are found abundantly in mesenchymal cells. Vimentin intermediate filaments localize primarily in the cytoplasm but can also be found on the cell ...
Ranu Surolia, Veena B. Antony
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The “Third Violin” in the Cytoskeleton Orchestra—The Role of Intermediate Filaments in the Endothelial Cell’s Life [PDF]
Biomedicines, 2022 The endothelium plays an important role in the transcytosis of lipoproteins. According to one of the theories, endothelial injury is a triggering factor for the development of atherosclerosis, and intracellular structures, including components of the ...
Anton S. Shakhov, Irina B. Alieva
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History and phylogeny of intermediate filaments: Now in insects [PDF]
BMC Biology, 2011 Intermediate filaments include the nuclear lamins, which are universal in metazoans, and the cytoplasmic intermediate filaments, which are much more varied and form cell type-specific networks in animal cells.
Strelkov Sergei V, Herrmann Harald
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Vimentin intermediate filaments stabilize dynamic microtubules by direct interactions [PDF]
Nature Communications, 2021 The tasks of the cytoskeleton depend on the fine-tuned interplay between the three filamentous components: actin filaments, microtubules, and intermediate filaments.
Laura Schaedel +4 more
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A tailored fit: How intermediate filaments orchestrate glioblastoma invasion [PDF]
Mechanobiology in MedicineGlioblastoma (GBM) is a highly invasive tumour. Invasion of GBM cells into the densely packed brain parenchyma reflects a profound mechanobiological adaptation to the mechanical constraints of the brain. A recent study by van Bodegraven et al.
Jessy V. van Asperen, Elly M. Hol
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Sacsin Deletion Induces Aggregation of Glial Intermediate Filaments [PDF]
Cells, 2022 Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is a neurodegenerative disorder commonly diagnosed in infants and characterized by progressive cerebellar ataxia, spasticity, motor sensory neuropathy and axonal demyelination.
Fernanda Murtinheira +9 more
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The importance of intermediate filaments in the shape maintenance of myoblast model tissues [PDF]
eLife, 2022 Liquid and elastic behaviours of tissues drive their morphology and response to the environment. They appear as the first insight into tissue mechanics.
Irène Nagle +5 more
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Intermediate Filaments in Breast Cancer Progression, and Potential Biomarker for Cancer Therapy: A Narrative Review [PDF]
Breast Cancer: Targets and TherapyWidad Aghnia Shalannandia,1 Yoan Chou,2 Muhammad Hasan Bashari,1,3 Astrid Feinisa Khairani1,3 1Graduate School of Master Program in Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Sumedang, Jatinangor, West Java, Indonesia; 2Graduate ...
Shalannandia WA +3 more
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The Diversity of Intermediate Filaments in Astrocytes [PDF]
Cells, 2020 Despite the remarkable complexity of the individual neuron and of neuronal circuits, it has been clear for quite a while that, in order to understand the functioning of the brain, the contribution of other cell types in the brain have to be accounted for.
Maja Potokar +3 more
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