Results 21 to 30 of about 5,857 (224)

Chemogenetic control of GABAergic neurons within the interpeduncular nucleus reveals dissociable behavioral components of the nicotine withdrawal phenotype

Neurobiology of Disease
Chronic exposure to nicotine results in the development of a dependent state such that a withdrawal syndrome is elicited upon cessation of nicotine. The interpeduncular nucleus (IPN) contains a high concentration of nicotinic acetylcholine receptors ...
Anabel M.M. Miguelez Fernández, Shana Netherton, Seshadri B. Niladhuri, Alexander C. Brown, Patricia Rivera, Kuei Y. Tseng, Christian J. Peters   +6 more
doaj   +2 more sources

Sex differences in cholinergic systems in the interpeduncular nucleus following nicotine exposure and withdrawal. [PDF]

Neuropharmacology, 2019
Correa VL, Flores RJ, Carcoba LM, Arreguin MC, O'Dell LE.   +4 more
europepmc   +3 more sources

SINGLE INTERPEDUNCULAR NUCLEUS CELLS INTEGRATE CHOLINERGIC AND RELAXIN-3 SIGNALING – POSSIBLE ROLE IN FAMILIARITY/NOVELTY AND STRESS PROCESSING

IBRO Neuroscience Reports, 2023
Gabriela Stopka, Patryk Sambak, Aleksandra Trenk, Anna Gugula, Angelika Kaleta, Andrew Gundlach, Mohammed Hossain, Anna Blasiak   +7 more
doaj   +2 more sources

The neural pathway from the superior subpart of the medial habenula to the interpeduncular nucleus suppresses anxiety. [PDF]

Mol Psychiatry
Handa T, Sugiyama T, Islam T, Johansen JP, Yanagawa Y, McHugh TJ, Okamoto H.   +6 more
europepmc   +3 more sources

Distribution of mRNA for the exocytotic calcium sensor, synaptotagmin 9, in mouse brain [PDF]

IBRO Neuroscience Reports
The principal Ca2 + sensors that control fusion of synaptic vesicles are synaptotagmins 1, 2 and 9. Synaptotagmin 9 (Syt9) has received the least attention. We applied RNAscope techniques to coronal sections of adult mouse brain to study the distribution
Kwadwo O. Boateng, Lucian D. Hadford, Kelly L. Stauch, Anthony E. Kincaid, Wallace B. Thoreson   +4 more
doaj   +2 more sources

Complex opioid-driven modulation of glutamatergic and cholinergic neurotransmission in a GABAergic brain nucleus associated with emotion, reward, and addiction [PDF]

eLife
The medial habenula (mHb)/interpeduncular nucleus (IPN) circuitry is resident to divergent molecular, neurochemical, and cellular components which, in concert, perform computations to drive emotion, reward, and addiction behaviors.
Ramesh Chittajallu, Anna Vlachos, Adam P Caccavano, Xiaoqing Yuan, Steven Hunt, Daniel Abebe, Edra London, Kenneth A Pelkey, Chris J McBain   +8 more
doaj   +2 more sources

Amino acid systems in the interpeduncular nucleus are altered in a sex-dependent manner during nicotine withdrawal. [PDF]

J Neurosci Res, 2022
Carcoba LM, Uribe KP, Ortegon S, Mendez IA, DeBiasi M, O'Dell LE.   +5 more
europepmc   +3 more sources

The interpeduncular nucleus blunts the rewarding effect of nicotine [PDF]

Neuron, 2023
SummaryNicotine, by stimulating ventral tegmental area (VTA) dopaminergic neurons, has a rewarding effect that drives tobacco consumption. In turn, the interpeduncular nucleus (IPN) is thought to become activated at high nicotine doses to restrict drug intake.
Joachim Jehl, Maria Ciscato, Éléonore Vicq, Gabrielle Dejean de la Bâtie, Nicolas Guyon, Sarah Mondoloni, Jacinthe Frangieh, Claire Nguyen, Jean‐Pierre Hardelin, Fabio Marti, Pierre‐Jean Corringer, Philippe Fauré, Alexandre Mourot   +12 more
openalex   +4 more sources

Trans-Synaptic Virus Tracing Reveals Reciprocal Connections of the Interpeduncular Nucleus With the Mood, Exteroceptive, Interoceptive, and Motor Control Systems. [PDF]

J Comp Neurol
The interpeduncular nucleus (IPN) in zebrafish plays a pivotal role in directional decision‐making, social conflict, and fear responses. The anterograde and retrograde connections of the dorsal and intermediate IPN are revealed through the use of monosynaptic and trans‐synaptic viral tracers.
Wong AK, Cherng BW, Kakinuma H, Wyart C, Okamoto H.   +4 more
europepmc   +2 more sources

Activation of GABAergic neurons in the interpeduncular nucleus triggers physical nicotine withdrawal symptoms. [PDF]

Curr Biol, 2013
Zhao-Shea R, Liu L, Pang X, Gardner PD, Tapper AR.   +4 more
europepmc   +3 more sources