Results 11 to 20 of about 30,763 (263)
Visualization of murine intranasal dosing efficiency using luminescent Francisella tularensis: effect of instillation volume and form of anesthesia. [PDF]
PLoS ONE, 2012 Intranasal instillation is a widely used procedure for pneumonic delivery of drugs, vaccine candidates, or infectious agents into the respiratory tract of research mice.
Mark A Miller +7 more
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Recent Advances in Intranasal Liposomes for Drug, Gene, and Vaccine Delivery
Pharmaceutics, 2023 Liposomes are safe, biocompatible, and biodegradable spherical nanosized vesicles produced from cholesterol and phospholipids. Recently, liposomes have been widely administered intranasally for systemic and brain delivery. From the nasal cavity, liposome-
Van-An Duong +2 more
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Frontiers in Pharmacology, 2022 The intranasal route has emerged as a promising strategy that can direct delivery of drugs into the systemic circulation because the high-vascularized nasal cavity, among other advantages, avoids the hepatic first-pass metabolism.
Jeehye Maeng, Kyunglim Lee
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Functional Hybrid Nanoemulsions for Sumatriptan Intranasal Delivery [PDF]
Frontiers in Chemistry, 2020 في السنوات الأخيرة، أثبتت المواد الهجينة النانوية المتقدمة التي تمت معالجتها كمستحضرات صيدلانية أنها مفيدة للغاية. التريبتان، مثل السوماتريبتان داخل الأنف المتاح تجاريًا (SMT)، هي أدوية تستخدم في علاج أعراض الصداع النصفي المؤلمة. ومع ذلك، فإن فعالية SMT محدودة بسبب أليفتها العالية للماء وضعف التصاق الغشاء المخاطي.
Lígia Nunes de Morais Ribeiro +8 more
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Pharmaceutics, 2023 Intranasal delivery of drugs offers several potential benefits related to ease of delivery, rapid onset, and patient experience, which may be of particular relevance to patients with central nervous system (CNS) conditions who experience acute events ...
Stuart Madden +2 more
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Design and Application in Delivery System of Intranasal Antidepressants
Frontiers in Bioengineering and Biotechnology, 2020 One of the major reasons why depressed patients fail their treatment course is the existence of the blood-brain barrier (BBB), which prevents drugs from being delivered to the central nervous system (CNS).
Jingying Xu +4 more
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Zaporožskij Medicinskij Žurnal, 2021 Development of novel medications for delivery of active ingredients with systemic absorption and high bioavailability is an actual challenge for modern pharmaceutical and medical science.
B. S. Burlaka, I. F. Bielenichev
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Strategies for intranasal delivery of vaccines [PDF]
Drug Delivery and Translational Research, 2012 The vast majority of human pathogens colonize and invade at the mucosal surfaces. Preventing infection at these sites via mucosally active vaccines is a promising and rational approach for vaccine development. However, it is only recently that the stimulation of local immunity at the mucosal surfaces has become a primary objective in addition to ...
Zaman, Mehfuz +2 more
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Intranasal Polymeric and Lipid-Based Nanocarriers for CNS Drug Delivery
Pharmaceutics, 2023 Nanomedicine is currently focused on the design and development of nanocarriers that enhance drug delivery to the brain to address unmet clinical needs for treating neuropsychiatric disorders and neurological diseases.
Rebecca Maher +5 more
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Intranasal Delivery of Nanoformulations: A Potential Way of Treatment for Neurological Disorders
Molecules, 2020 Although the global prevalence of neurological disorders such as Parkinson’s disease, Alzheimer’s disease, glioblastoma, epilepsy, and multiple sclerosis is steadily increasing, effective delivery of drug molecules in therapeutic quantities to the ...
Salman Ul Islam +3 more
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