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Potential of Nanoparticulate Drug Delivery Systems by Intranasal Administration
Current Pharmaceutical Design, 2010 Due to number of problems related with oral, parenteral, rectal and other routes of drug administration, the interest of pharmaceutical scientists has increased towards exploring the possibilities of intranasal delivery of various drugs. Nasal drug delivery system is commonly known for the treatment of local ailments like cold, cough, rhinitis, etc ...
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Intranasal drug delivery for treatment of Alzheimer’s disease
Drug Delivery and Translational Research, 2021The Alzheimer's disease is a neurodegenerative condition with severe consequences interfering with patient quality of life. It is characterized as a progressive and irreversible brain disorder hampering memory and thinking, affecting the capacity to perform daily tasks leading to physical and cognitive incapacitation.
Fonseca, Leonor Cancela +6 more
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Intranasal delivery of antipsychotic drugs
Schizophrenia Research, 2017Antipsychotic drugs are used to treat psychotic disorders that afflict millions globally and cause tremendous emotional, economic and healthcare burdens. However, the potential of intranasal delivery to improve brain-specific targeting remains unrealized. In this article, we review the mechanisms and methods used for brain targeting via the intranasal (
Yogesh K. Katare +7 more
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Nanotechnologies for intranasal drug delivery: an update of literature
Pharmaceutical Development and Technology, 2021Scientific research has focused its attention on finding an alternative route to systemic oral and parenteral administration, to overcome their usual drawbacks, such as hepatic first-pass which decreases drug bioavailability after oral administration, off-target effects, low patient compliance and low speed of onset of the pharmacological action in ...
Lombardo R. +3 more
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Clinical Research and Regulatory Affairs, 1993
AbstractThe intranasal administration of drugs is a promising alternative to parenteral administration. The nasal route represents an interesting alternative for drugs which have low oral bioavailability because of degradation in GI tract or extensive mucosal or first-pass metabolism.
H. Zia, P. Dondeti, T. E. Needham
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AbstractThe intranasal administration of drugs is a promising alternative to parenteral administration. The nasal route represents an interesting alternative for drugs which have low oral bioavailability because of degradation in GI tract or extensive mucosal or first-pass metabolism.
H. Zia, P. Dondeti, T. E. Needham
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Intranasal Drug Delivery for Brain Targeting
Current Drug Delivery, 2005Many drugs are not being effectively and efficiently delivered using conventional drug delivery approach to brain or central nervous system (CNS) due to its complexity. The brain and the central nervous system both have limited accessibility to blood compartment due to a number of barriers.
Tushar K, Vyas +3 more
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Advanced Drug Delivery Reviews, 1998
In recent years the nasal route has received a great deal of attention as a convenient and reliable method for the systemic administration of drugs. Although this route is currently being marketed for the systemic administration of several drugs, it has only recently been studied.
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In recent years the nasal route has received a great deal of attention as a convenient and reliable method for the systemic administration of drugs. Although this route is currently being marketed for the systemic administration of several drugs, it has only recently been studied.
openaire +2 more sources
Intranasal delivery of drugs to eustachian tube orifice
The Journal of Laryngology & Otology, 2011AbstractBackground:Intranasal medication administration which aims to deliver to the eustachian tube orifice has been adopted for the management of a number of otological conditions, acting via a reduction in tubal oedema and improved ventilation. Evidence for the optimal head position for such drug administration is limited. We compared four different
Y G, Karagama +4 more
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Strategies for the delivery of antidiabetic drugs via intranasal route
International Journal of Pharmaceutics, 2021Diabetes is a metabolic disorder defined by higher blood glucose levels in the body generally controlled by antidiabetic agents (oral) and insulin (subcutaneous). To avoid the limitations of the conventional routes such as lower bioavailability and pain at the site of injection in case of parenteral route modified delivery systems are proposed like ...
Jheel, Dholakia +2 more
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Clinical Pharmacokinetics, 1989
Utilisation de la forme intranasale pour administrer les hormones peptides et d'autres medicaments.
A E, Pontiroli, A, Calderara, G, Pozza
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Utilisation de la forme intranasale pour administrer les hormones peptides et d'autres medicaments.
A E, Pontiroli, A, Calderara, G, Pozza
openaire +2 more sources