An LNP antiviral siRNA drug cocktail delivered intranasally is effective against a range of respiratory viruses. [PDF]
Oti VB +7 more
europepmc +1 more source
Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
Jessie Kim +2 more
wiley +1 more source
Peptide-Based Therapeutics for Alzheimer's Disease: Medicinal Chemistry, AI-Guided Computational Design, and Blood-Brain Barrier Delivery. [PDF]
Al Khzem AH, Gomaa MS.
europepmc +1 more source
Intranasal Vaccine Adjuvants and Delivery Platforms: From Barrier Mechanisms to Clinical Translation. [PDF]
Yao S +6 more
europepmc +1 more source
Is "Just-in-Case" catheterisation inappropriate or system-driven? A human factors perspective. [PDF]
Galant J, Cazes N, Renard A.
europepmc +1 more source
Ex Vivo Characterization and In Vivo Nasal Delivery of Ropinirole-Loaded PEO-b-PCL/Tween 80/β-Cyclodextrin Systems in C57BL/6J Mice. [PDF]
Saitani EM +8 more
europepmc +1 more source
Lipid Nanoparticles for Nasal/Intranasal Drug Delivery
Studies on the development of drug delivery systems have increased because these systems have particular characteristics that allow them to improve therapeutics. Among these, lipid nanoparticles (solid lipid nanoparticles, SLNs; and nanostructured lipid carriers, NLCs) have demonstrated suitability for drug targeting.
Sara C Cunha +2 more
exaly +5 more sources
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Mechanism of intranasal drug delivery directly to the brain
Life Sciences, 2018Neurological diseases are becoming increasingly prominent worldwide due to rapidly aging populations, which greatly contributes to increasing healthcare costs. The development of neuroprotective drugs has so far proven exceptionally difficult due to the blood-brain barrier.
Tyler P Crowe +2 more
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Intranasal Drug Delivery: A Non-Invasive Approach for the Better Delivery of Neurotherapeutics
Pharmaceutical Nanotechnology, 2018The convoluted pathophysiology of brain disorders along with penetration issue of drugs to brain represents major hurdle that requires some novel therapies. The blood-brain barrier (BBB) denotes a rigid barrier for delivery of therapeutics in vivo; to overcome this barrier, intranasal delivery is an excellent strategy to deliver the drug directly to ...
Hitesh Kumar +2 more
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