Results 11 to 20 of about 1,811,289 (287)
Intrinsic Disorder in Transcription Factors [PDF]
Biochemistry, 2006 Intrinsic disorder (ID) is highly abundant in eukaryotes, which reflect the greater need for disorder-associated signaling and transcriptional regulation in nucleated cells.
Su, Eric W. +5 more
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SnapShot: Intrinsic Structural Disorder. [PDF]
Cell, 2015 Many proteins (intrinsically disordered proteins, IDPs) or regions of proteins (intrinsically disordered regions, IDRs) lack a well-defined 3D structure under physiological conditions. Albeit unfolded and highly dynamic, these proteins are not denatured;
Guharoy, M. +4 more
core +4 more sources
Intrinsic structural disorder in cytoskeletal proteins. [PDF]
Cytoskeleton, 2013 Cytoskeleton, the internal scaffold of the cell, displays an exceptional combination of stability and dynamics. It is composed of three major filamentous networks, microfilaments (actin filaments), intermediate filaments (neurofilaments), and ...
Szabó, Beáta +3 more
core +6 more sources
Computational Analysis and Prediction of Intrinsic Disorder and Intrinsic Disorder Functions in Proteins [PDF]
, 2021 COMPUTATIONAL ANALYSIS AND PREDICTION OF INTRINSIC DISORDER AND INTRINSIC DISORDER FUNCTIONS IN PROTEINS By Akila Imesha Katuwawala A dissertation submitted in partial fulfillment of the requirements for the degree of Engineering, Doctor of Philosophy ...
Katuwawala, Akila I
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Troponins, Intrinsic Disorder, and Cardiomyopathy
Biological Chemistry, 2016 Cardiac troponin is a dynamic complex of troponin C, troponin I, and troponin T (TnC, TnI, and TnT, respectively) found in the myocyte thin filament where it plays an essential role in cardiac muscle contraction.
Uversky, Vladimir N. +4 more
core +4 more sources
Intrinsic Disorder of The Extracellular Matrix
Molecular BioSystems, 2011 The extracellular matrix is very well organized at the supramolecular and tissue levels and little is known on the potential role of intrinsic disorder in promoting its organization.
Uversky, Vladimir N. +3 more
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Intrinsic disorder in the human spliceosomal proteome.
PLoS Computational Biology, 2012 The spliceosome is a molecular machine that performs the excision of introns from eukaryotic pre-mRNAs. This macromolecular complex comprises in human cells five RNAs and over one hundred proteins.
Janusz M Bujnicki +3 more
core +5 more sources
Exploring protein intrinsic disorder with mobidb
, 2020 Nowadays, it is well established that many proteins or regions under physiological conditions lack a fixed three-dimensional structure and are intrinsically disordered. MobiDB is the main repository of protein disorder and mobility annotations, combining
András Hatos +9 more
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Intrinsic disorder in putative protein sequences [PDF]
Proteome Science, 2012 © 2012 Midic and Obradovic; licensee BioMed Central Ltd. Background: Intrinsically disordered proteins (IDPs) and regions (IDRs) perform a variety of crucial biological functions despite lacking stable tertiary structure under physiological conditions in
Zoran Obradovic +3 more
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Intrinsic Disorder in the Human Tear Proteome. [PDF]
Invest Ophthalmol Vis Sci, 2023 PurposeWe aimed to characterize the proteome of human tears and assess for the presence of intrinsically disordered proteins (IDPs). IDPs, despite lacking a rigid three-dimensional structure, maintain biological functionality and could shed light on the ...
Taylor Gonzalez DJ +8 more
europepmc +2 more sources