Results 11 to 20 of about 2,160,956 (299)
Intrinsic Disorder in Transcription Factors [PDF]
Biochemistry, 2006 Intrinsic disorder (ID) is highly abundant in eukaryotes, which reflect the greater need for disorder-associated signaling and transcriptional regulation in nucleated cells.
Su, Eric W. +5 more
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Protein intrinsic disorder in plants
Frontiers in Plant Science, 2013 To some extent contradicting the classical paradigm of the relationship between protein 3D structure and function, now it is clear that large portions of the proteomes, especially in higher organisms, lack a fixed structure and still perform very ...
Florencio ePazos +3 more
doaj +4 more sources
SnapShot: Intrinsic Structural Disorder.
Cell, 2015 Many proteins (intrinsically disordered proteins, IDPs) or regions of proteins (intrinsically disordered regions, IDRs) lack a well-defined 3D structure under physiological conditions. Albeit unfolded and highly dynamic, these proteins are not denatured;
Guharoy, M., Pauwels, K., Tompa, Péter
core +4 more sources
Intrinsic structural disorder in cytoskeletal proteins. [PDF]
Cytoskeleton, 2013 Cytoskeleton, the internal scaffold of the cell, displays an exceptional combination of stability and dynamics. It is composed of three major filamentous networks, microfilaments (actin filaments), intermediate filaments (neurofilaments), and ...
Szabó, Beáta +3 more
core +6 more sources
Intrinsic Disorder of The Extracellular Matrix
Molecular BioSystems, 2011 The extracellular matrix is very well organized at the supramolecular and tissue levels and little is known on the potential role of intrinsic disorder in promoting its organization.
Uversky, Vladimir N. +3 more
core +4 more sources
Exploring protein intrinsic disorder with mobidb
, 2020 Nowadays, it is well established that many proteins or regions under physiological conditions lack a fixed three-dimensional structure and are intrinsically disordered. MobiDB is the main repository of protein disorder and mobility annotations, combining
András Hatos +9 more
core +3 more sources
Computational Analysis and Prediction of Intrinsic Disorder and Intrinsic Disorder Functions in Proteins [PDF]
, 2021 COMPUTATIONAL ANALYSIS AND PREDICTION OF INTRINSIC DISORDER AND INTRINSIC DISORDER FUNCTIONS IN PROTEINS By Akila Imesha Katuwawala A dissertation submitted in partial fulfillment of the requirements for the degree of Engineering, Doctor of Philosophy ...
Katuwawala, Akila I
core +2 more sources
Intrinsic disorder in the human spliceosomal proteome.
PLoS Computational Biology, 2012 The spliceosome is a molecular machine that performs the excision of introns from eukaryotic pre-mRNAs. This macromolecular complex comprises in human cells five RNAs and over one hundred proteins.
Janusz M Bujnicki +5 more
core +5 more sources
Intrinsic Disorder in the Human Tear Proteome. [PDF]
Invest Ophthalmol Vis Sci, 2023 PurposeWe aimed to characterize the proteome of human tears and assess for the presence of intrinsically disordered proteins (IDPs). IDPs, despite lacking a rigid three-dimensional structure, maintain biological functionality and could shed light on the ...
Taylor Gonzalez DJ +8 more
europepmc +2 more sources
Evolution of Intrinsic Disorder in Protein Loops. [PDF]
Life (Basel), 2023 Intrinsic disorder accounts for the flexibility of protein loops, molecular building blocks that are largely responsible for the processes and molecular functions of the living world.
Mughal F, Caetano-Anollés G.
europepmc +2 more sources