Results 21 to 30 of about 948,947 (298)
Scientific Reports, 2019 The excitability of neurons is tightly dependent on their ion channel repertoire. Among these channels, the leak sodium channel NALCN plays a crucial role in the maintenance of the resting membrane potential.
Malik Bouasse +4 more
doaj +1 more source
Multiple Thresholds in a Model System of Noisy Ion Channels [PDF]
, 2006 Voltage-activated ion channels vary randomly between open and closed states, influenced by the membrane potential and other factors. Signal transduction is enhanced by noise in a simple ion channel model.
D. Johnston +5 more
core +1 more source
Langmuir, 2013 The objective of this historical review is to recall the development of the field of synthetic ion channels over the past three decades. The most inspiring and influential breakthroughs with regard to structure and function are brought together to give the general reader an easily accessible understanding of the field.
Sakai Naomi, Matile Stefan
openaire +5 more sources
VAMP7 regulates constitutive membrane incorporation of the cold-activated channel TRPM8
Nature Communications, 2016 The temperature-sensitive TRPM8 channel is essential for cold sensing and has been linked to pathological cold hypersensitivity. Here, the authors find TRPM8 insertion in the cell membrane is mediated by VAMP7 following atypical LAMP1-containing vesicle ...
Debapriya Ghosh +12 more
doaj +1 more source
Activity-dependent regulation of T-type calcium channels by submembrane calcium ions
eLife, 2017 Voltage-gated Ca2+ channels are involved in numerous physiological functions and various mechanisms finely tune their activity, including the Ca2+ ion itself.
Magali Cazade +3 more
doaj +1 more source
The diverse roles of TMEM16A Ca2+-activated Cl− channels in inflammation
Journal of Advanced Research, 2021 Background: Transmembrane protein 16A (TMEM16A) Ca2+-activated Cl− channels have diverse physiological functions, such as epithelial secretion of Cl− and fluid and sensation of pain.
Weiliang Bai, Mei Liu, Qinghuan Xiao
doaj +1 more source
Interplay between R513 methylation and S516 phosphorylation of the cardiac voltage-gated sodium channel [PDF]
, 2014 Arginine methylation is a novel post-translational modification within the voltage-gated ion channel superfamily, including the cardiac sodium channel, Naᵥ1.5.
Beltran-Alvarez, Pedro +5 more
core +3 more sources
eLife, 2016 Transient Receptor Potential Melastatin 2 (TRPM2) is a Ca2+-permeable cation channel essential for immunocyte activation, insulin secretion, and postischemic cell death.
Iordan Iordanov +3 more
doaj +1 more source
Pharmaceutical Biology, 2020 Context Ginsenoside Rb1, the main active ingredient of ginseng, exhibits ex vivo depression of store-operated calcium entry (SOCE) and related vasoconstriction in pulmonary arteries derived from pulmonary hypertension (PH) rats.
Rui-Xing Wang +8 more
doaj +1 more source