Results 41 to 50 of about 948,947 (298)
Charge fluctuations and boundary conditions of biological ion channels:effect on the ionic transition rate [PDF]
, 2009 A self-consistent solution is derived for the Poisson-Nernst-Planck (PNP) equation, valid both inside a biological ion channel and in the adjacent bulk fluid. An iterative procedure is used to match the two solutions together at the channel mouth. Charge
Eisenberg, R. S. +3 more
core +1 more source
Ubiquitylation of Ion Channels
Physiology, 2005 Ubiquitylation (i.e., covalent attachment of ubiquitin moieties to proteins) of ion channels allows regulation of their activity and fate. Nedd4/Nedd4-like ubiquitin-protein ligases bind to, ubiquitylate, and modulate the internalization of several channels bearing PY motifs, whereas endoplasmic reticulum-associated degradation (involving ...
Abriel H, Staub O
openaire +3 more sources
Frontiers in Molecular Biosciences, 2021 Mass spectrometry-based proteomics methods are widely used to identify and quantify protein complexes involved in diverse biological processes. Specifically, tandem mass spectrometry methods represent an accurate and sensitive strategy for identifying ...
Mariela González-Avendaño +21 more
doaj +1 more source
Human sperm ion channel (dys)function:implications for fertilization [PDF]
, 2019 BACKGROUND: Intensive research on sperm ion channels has identified members of several ion channel families in both mouse and human sperm. Gene knock-out studies have unequivocally demonstrated the importance of the calcium and potassium conductances in ...
Barratt, Christopher L. R. +3 more
core +4 more sources
Cell-specific mechanisms of TMEM16A Ca2+-activated chloride channel in cancer
Molecular Cancer, 2017 TMEM16A (known as anoctamin 1) Ca2+-activated chloride channel is overexpressed in many tumors. TMEM16A overexpression can be caused by gene amplification in many tumors harboring 11q13 amplification.
Hui Wang +6 more
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Antibiotics, 2023 One of the global challenges of the 21st century is the increase in mortality from infectious diseases against the backdrop of the spread of antibiotic-resistant pathogenic microorganisms.
Olga S. Ostroumova, Svetlana S. Efimova
doaj +1 more source
Voltage dependence of Hodgkin-Huxley rate functions for a multi-stage K channel voltage sensor within a membrane [PDF]
, 2014 The activation of a $K^+$ channel sensor in two sequential stages during a voltage clamp may be described as the translocation of a Brownian particle in an energy landscape with two large barriers between states.
Vaccaro, Samuel R.
core +2 more sources
New Challenges Resulting From the Loss of Function of Nav1.4 in Neuromuscular Diseases
Frontiers in Pharmacology, 2021 The voltage-gated sodium channel Nav1.4 is a major actor in the excitability of skeletal myofibers, driving the muscle force in response to nerve stimulation.
Sophie Nicole +3 more
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Self-consistent analytic solution for the current and the access resistance in open ion channels. [PDF]
, 2009 A self-consistent analytic approach is introduced for the estimation of the access resistance and the current through an open ion channel for an arbitrary number of species.
Kaufman, I. +3 more
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Electric Dipolar Kondo Effect Emerging from Vibrating Magnetic Ion
, 2012 When a magnetic ion vibrates in a metal, it inevitably introduces a new channel of hybridization with conduction electrons and in general, the vibrating ion induces electric dipole moment. In such a situation, we find that magnetic and non-magnetic Kondo
Hotta, Takashi, Ueda, Kazuo
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