Results 41 to 50 of about 81,945 (302)

Deletion analysis using BAC-IRF-8 reporter constructs points to the role of the 3rd intron in modulating lineage specific expression of IRF-8.

open access: yes, 2016
Schematic illustrations of the various BAC-IRF-8 constructs, to which a cassette containing a fluorescent reporter (mCherry) and a selectable marker (Neo driven by the PKG promoter) was inserted, are shown.
Mamduh Khateb (2816770)   +10 more
core   +1 more source

Accelerated Materials Discovery Through In Situ X‐ray Diffraction: Solvothermal Formation of PdxMy (M═Si, Ge, Sn, Pb) Intermetallic Nanoparticles

open access: yesAdvanced Materials, EarlyView.
In situ PXRD data on solvothermal reactions accelerate materials discovery while simultaneously providing fundamental insights into complex crystal formation processes. Using PdxMy (M = Si, Ge, Sn, Pb) as an example, a general formation mechanism is identified, and specific synthesis strategies for ex situ preparation of SnPd2, Sn13Pd20, and SnPd ...
Anders Bæk Borup   +1 more
wiley   +1 more source

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

open access: yesAdvanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green   +15 more
wiley   +1 more source

Research on diagnosis for vibration faults in steam turbines using IRF algorithm

open access: yesZhejiang dianli
The random forest algorithm, known for its robustness against noise and powerful computational capabilities, is widely employed in diagnosing vibration faults in rotating machinery.
LI Wei   +5 more
doaj   +1 more source

Transcriptional regulation of lipopolysaccharide (LPS)-induced Toll-like Receptor (TLR) expression in murine macrophages: role of interferon regulatory factors-1 (IRF-1) and 2 (IRF-2)

open access: yes, 2006
La activación de los receptores tipo Toll (TLRs) se asocia estrechamente con la inducción de la expresión génica proinflamatoria; sin embargo, también se ha demostrado que la expresión de muchos otros genes, incluidos los propios genes TLR, se modula ...
Nhu, Quan M   +2 more
core   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

open access: yesAdvanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li   +7 more
wiley   +1 more source

Interferon Regulatory Factor 1 (IRF-1) and IRF-2 Expression in Breast Cancer Tissue Microarrays [PDF]

open access: yes, 2005
Interferon-γ (IFN-γ) is a pleiotropic cytokine with potent antitumor effects, both in vitro and in vivo. The antitumor activity of IFN-γ is mediated in part through IFN regulatory factor-1 (IRF-1) and may be blocked by IRF-2.
Judith M. Connett   +9 more
core   +1 more source

Single‐Cell Dissection of Microglial Dysfunction in Diabetes‐Associated Neurodegenerative Vulnerability

open access: yesAdvanced Science, EarlyView.
Using single‐cell transcriptomic and epigenomic profiling, researchers mapped microglial dysfunction across the lifespan of db/db mice. The authors uncovered a nonlinear microglial remodeling featuring early inflammatory priming, a mid‐stage transcriptional inflection, and late dysfunction.
Jizhou Zhang   +6 more
wiley   +1 more source

RTGS Determinant & Sub-transaction Behavior during COVID-19 in Indonesia

open access: yesBuletin Ekonomi Moneter dan Perbankan
This paper investigates external factors affecting Indonesia’s Real Time Gross Settlement (RTGS) transactions by applying machine learning regularization to identify key variables from a large dataset. A Vector AutoRegression (VAR) model analyzes dynamic
Bastian Muzbar Zams   +4 more
doaj   +1 more source

Perioperative intraretinal fluid observed using optical coherence tomography in the epiretinal membrane

open access: yesBMC Ophthalmology, 2020
Background Postoperative intraretinal fluid (IRF) is reportedly associated with visual outcomes after epiretinal membrane (ERM) surgery. However, preoperative IRF is common, and persistent IRF would have different impact on visual function from ...
Jae Jung Lee   +6 more
doaj   +1 more source

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