Results 1 to 10 of about 6,913 (99)

Engineered long-acting Irisin-albumin binding domain fusion protein for enhanced anti-inflammatory efficacy in lipopolysaccharide-induced systemic inflammation [PDF]

Communications Biology
Irisin is a peptide hormone with notable anti-inflammatory and metabolic regulatory effects but has limited clinical utility due to its extremely short plasma half-life (< 1 h).
Jicun Zhu, Yujie Zhang, Xinwei Wang, Lei Peng, Xiaojia Ma, Zan Qiu, Zirui Kang, Fangyuan Zheng, Xiaoyu Zhang, Mengyuan Song, Jia Du, Yuan Shi, Lie Yu, Chenxi Gu, Jianxiang Shi   +14 more
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Role of Irisin in Myocardial Infarction, Heart Failure, and Cardiac Hypertrophy

Cells, 2021
Irisin is a myokine derived from the cleavage of fibronectin type III domain-containing 5. Irisin regulates mitochondrial energy, glucose metabolism, fatty acid oxidation, and fat browning.
Ming-Yun Ho, Chao-Yung Wang
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Relationship between serum irisin level, all-cause mortality, and cardiovascular mortality in peritoneal dialysis patients

Kidney & Blood Pressure Research, 2023
Introduction: This study aimed to investigate the prospective role of serum irisin-a novel adipo-myokine-in all-cause mortality and cardiovascular (CV) mortality in patients on peritoneal dialysis (PD).
Sijia Zhou, Wen Tang, Xiaoxiao Wang, Qingfeng Han, Qiong Bai, Aihua Zhang   +5 more
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Relationship of serum irisin levels and various demographic and biochemical factors in non-diabetic hemodialysis patients [PDF]

Journal of Preventive Epidemiology, 2020
Introduction: Irisin is a myokine secreted from the skeletal muscle. Preliminary studies showed that the serum irisin level was decreased in patients with chronic kidney disease (CKD), particularly in hemodialysis patients.
Fereshteh Rafi’i, Seyed Mohsen Hosaini, Banafsheh Yalameha, Hamid Nasri   +3 more
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Roles and Mechanisms of Irisin in Attenuating Pathological Features of Osteoarthritis

Frontiers in Cell and Developmental Biology, 2021
To investigate the effects and mechanisms of irisin, a newly discovered myokine, in cartilage development, osteoarthritis (OA) pathophysiology and its therapeutic potential for treating OA we applied the following five strategical analyses using (1 ...
Xiangfen Li, Xiangfen Li, Xiaofang Zhu, Hongle Wu, Hongle Wu, Thomas E. Van Dyke, Thomas E. Van Dyke, Xiaoyang Xu, Elise F. Morgan, Wenyu Fu, Wenyu Fu, Chuanju Liu, Chuanju Liu, Qisheng Tu, Dingming Huang, Jake Chen   +15 more
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Circulating Irisin Levels in Patients with Chronic Plaque Psoriasis

Biomolecules, 2022
Irisin is an adipo-myokine, mainly synthetized in skeletal muscles and adipose tissues, that is involved in multiple processes. Only a few studies have evaluated serum irisin in psoriatic patients.
Francesca Ambrogio, Lorenzo Sanesi, Angela Oranger, Chiara Barlusconi, Manuela Dicarlo, Patrizia Pignataro, Roberta Zerlotin, Paolo Romita, Elvira Favoino, Gerardo Cazzato, Nicoletta Cassano, Gino Antonio Vena, Caterina Foti, Maria Grano   +13 more
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The optimal therapeutic irisin dose intervention in animal model: A systematic review [PDF]

Veterinary World, 2020
Background and Aim: Irisin, a novel myocyte-secreted hormone, was proposed to mediate some of the beneficial effects of exercise such as browning of adipocytes, thermogenesis, and metabolic homeostasis.
Foad Alzoughool, Mohammad Borhan Al-Zghoul, Saad Al-Nassan, Lo'ai Alanagreh, Dana Mufleh, Manar Atoum   +5 more
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Inverse correlation between serum irisin and cardiovascular risk factors among Chinese overweight/obese population

BMC Cardiovascular Disorders, 2021
Background Irisin is a novel myokine associated with obesity, which is a traditional cardiovascular risk factor (CVRF). The present study aimed to investigate the association between serum irisin and a single CVRF as well as the clustering of CVRFs among
Ruoyi Liu, Qiao Zhang, Nianchun Peng, Shujing Xu, Miao Zhang, Ying Hu, Zhengyi Chen, Kun Tang, Xi He, Yi Li, Lixin Shi   +10 more
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The effects of 8-week resistance and endurance trainings on bone strength compared to irisin injection protocol in mice

Advanced Biomedical Research, 2021
Background: Osteoporosis is a prevalent elderly complication that is characterized by decreased bone mineral density and increased fracture risk because of dysregulation in bone mineralization and resorption.
Shirin Shahabi, Fahimeh Esfarjani, Jalil Reisi, Sedigheh Momenzadeh, Mohammad-Saeid Jami, Saeed Zamani   +5 more
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Serum irisin levels increase in girls with central precocious puberty not dependent on BMI: a pilot study

Endocrine Connections, 2022
Objective: The objective of this study is to investigate the role of seru m irisin level in diagnosis of central precocious puberty (CPP) in girls and its major determinants.
Yanfei Chen, Mei Li, Binrong Liao, Jingzi Zhong, Dan Lan   +4 more
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