Irisin is a pro-myogenic factor that induces skeletal muscle hypertrophy and rescues denervation-induced atrophy [PDF]
, 2017 Exercise induces expression of the myokine irisin, which is known to promote browning of white adipose tissue and has been shown to mediate beneficial effects following exercise. Here we show that irisin induces expression of a number of pro-myogenic and
Ge, Xiaojia +7 more
core +5 more sources
Irisin exhibits neuroprotection by preventing mitochondrial damage in Parkinson’s disease
npj Parkinson's Disease, 2023 Exercise has been proposed as an effective non-pharmacological management for Parkinson’s disease (PD) patients. Irisin, a recently identified myokine, is increased by exercise and plays pivotal roles in energy metabolism.
Xi Zhang +8 more
doaj +2 more sources
Circulating Sclerostin and Irisin Are Related and Interact with Gender to Influence Adiposity in Adults with Prediabetes [PDF]
International Journal of Endocrinology, 2014 Objectives. Sclerostin, an osteocyte-specific protein, has been found to be related to adiposity and glucose metabolism. Irisin, a myokine, can affect browning of white fat and influence glucose and energy homeostasis.
Theerawut Klangjareonchai +7 more
doaj +2 more sources
Salivary and serum irisin in healthy adults before and after exercise
European Journal of Translational Myology, 2023 Irisin is an exercise-induced cytokine mainly secreted by myocytes. Circulating level of irisin can increase in response to acute exercise, promoting pleiotropic effects on health.
Sara Missaglia +7 more
doaj +2 more sources
Beneficial effect of voluntary exercise on experimental colitis in mice fed a high-fat diet : the role of irisin, adiponectin and proinflammatory biomarkers [PDF]
, 2017 Inflammatory bowel diseases (IBDs) are a heterogeneous group of disorders exhibited by two major phenotypic forms: Crohn‘s disease and ulcerative colitis.
Bilski, Jan +10 more
core +3 more sources
Expressions of irisin and urotensin II and their relationships with blood pressure in patients with preeclampsia [PDF]
Clinical and Experimental Hypertension, 2017 The aims of this study are to observe irisin and urotensin II (UII) levels in serum and placenta in normal pregnant and preeclamptic women and investigate the relationship between expressions irisin and UII, and their association with blood pressure.
Li-Jie Zhang +3 more
doaj +2 more sources
Serum levels of the adipomyokine irisin in patients with chronic kidney disease [PDF]
Nefrología (English Edition), 2016 Background: Irisin is an adipomyokine with claimed anti-obesity and anti-diabetic effects. This hormone has been insufficiently studied in patients with advanced chronic kidney disease (CKD).
Ana Rodríguez-Carmona +6 more
doaj +6 more sources
Evolutionary Insights into Irisin/FNDC5: Roles in Aging and Disease from Drosophila to Mammals [PDF]
BiomoleculesThe Irisin/FNDC5 protein family has emerged as a pivotal link between exercise and the prevention of age-associated diseases. Irisin is highly expressed during exercise from skeletal and cardiac muscle cells, playing a critical role in mediating systemic
Kiwon Lee, Myungjin Kim
doaj +2 more sources
SNPs in FNDC5 (irisin) are associated with obesity and modulation of glucose and lipid metabolism in Saudi subjects [PDF]
, 2016 Nasser M. Al‐Daghri +6 more
core +3 more sources
Kidney & Blood Pressure Research, 2023 Introduction: This study aimed to investigate the prospective role of serum irisin-a novel adipo-myokine-in all-cause mortality and cardiovascular (CV) mortality in patients on peritoneal dialysis (PD).
Sijia Zhou +5 more
doaj +1 more source