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Relationship of serum irisin levels and various demographic and biochemical factors in non-diabetic hemodialysis patients [PDF]
Introduction: Irisin is a myokine secreted from the skeletal muscle. Preliminary studies showed that the serum irisin level was decreased in patients with chronic kidney disease (CKD), particularly in hemodialysis patients.
Fereshteh Rafi’i+3 more
doaj +1 more source
Irisin Levels Are Lower in Young Amenorrheic Athletes Compared with Eumenorrheic Athletes and Non-Athletes and Are Associated with Bone Density and Strength Estimates [PDF]
Irisin and FGF21 are novel hormones implicated in the “browning” of white fat, thermogenesis, and energy homeostasis. However, there are no data regarding these hormones in amenorrheic athletes (AA) (a chronic energy deficit state) compared with ...
Ackerman, Kathryn E.+10 more
core +12 more sources
Circulating Irisin Levels in Patients with Chronic Plaque Psoriasis
Irisin is an adipo-myokine, mainly synthetized in skeletal muscles and adipose tissues, that is involved in multiple processes. Only a few studies have evaluated serum irisin in psoriatic patients.
Francesca Ambrogio+13 more
doaj +1 more source
Irisin and betatrophin responses to 9 h of passive heat exposure: Influence of age, hypertension, and type 2 diabetes. [PDF]
Abstract Age‐ and disease‐related metabolic responses to prolonged passive heat exposure are poorly understood. We evaluated serum irisin and betatrophin responses to 9 h of passive heat exposure (40°C, 9% relative humidity) in 19 young adults (19–31 years) and 37 older adults (61–78 years), including those with hypertension (HTN) and type 2 diabetes ...
Garrett JM+7 more
europepmc +2 more sources
The Role of Irisin in Cancer Disease [PDF]
Irisin (Ir) is an adipomyokine that is involved in the regulation of metabolic processes. It also influences processes related to inflammation, including cancer. Initially, Ir was considered a hormone secreted by skeletal muscles in response to physical exercise.
Agnieszka Pinkowska+3 more
openaire +4 more sources
The optimal therapeutic irisin dose intervention in animal model: A systematic review [PDF]
Background and Aim: Irisin, a novel myocyte-secreted hormone, was proposed to mediate some of the beneficial effects of exercise such as browning of adipocytes, thermogenesis, and metabolic homeostasis.
Foad Alzoughool+5 more
doaj +1 more source
Irisin: ‘fat’ or artefact [PDF]
SummarySoon after the discovery of the muscle‐derived factor irisin, a great controversy arose in the literature regarding certain inconsistencies in the regulation of the fibronectin type III domain containing 5 protein (FNDC5/irisin) after exercise, as well as the unpredicted association of circulating irisin levels with parameters of adiposity in ...
Felipe F. Casanueva+2 more
openaire +4 more sources
Roles and Mechanisms of Irisin in Attenuating Pathological Features of Osteoarthritis
To investigate the effects and mechanisms of irisin, a newly discovered myokine, in cartilage development, osteoarthritis (OA) pathophysiology and its therapeutic potential for treating OA we applied the following five strategical analyses using (1 ...
Xiangfen Li+15 more
doaj +1 more source
Background Irisin is a novel myokine associated with obesity, which is a traditional cardiovascular risk factor (CVRF). The present study aimed to investigate the association between serum irisin and a single CVRF as well as the clustering of CVRFs among
Ruoyi Liu+10 more
doaj +1 more source
Increasing energy expenditure is an attractive approach to fighting the worldwide epidemic in obesity and type 2 diabetes. Exercise is an important component of good health and represents the first line of therapy for humans with a variety of metabolic disorders: obesity, diabetes, and nonalcoholic hepatic steatosis. Recent data has shown that exercise,
Wu, Jun, Spiegelman, Bruce
openaire +4 more sources