Results 31 to 40 of about 5,686 (117)
Experimental Physiology, EarlyView.Abstract Hepatic ischaemia–reperfusion (IR) injury is a serious clinical issue, especially in patients with type 2 diabetes mellitus (T2DM). As mitochondria play a critical role in the regulation of IR‐induced liver damage, mitochondria‐targeted treatment is of the utmost significance for improving outcomes.
Jie Lin +4 more
wiley +1 more source
İrisin ve Vasküler Kontraktilite Üzerine Etkileri
SDÜ Tıp Fakültesi Dergisi, 2021 Bu derleme, irisin hakkındaki mevcut bilgileri ve irisinin vasküler tonusa aracılık etmedeki etkin rolünü özetleme çabasıdır. Egzersiz kronik, bulaşıcı olmayan hastalıkların, tip 2 diyabetin ve özellikle kardiyovasküler hastalıkların önlenmesinde bir dayanak noktasıdır.
DEMİREL, Sadettin +3 more
openaire +6 more sources
Experimental Physiology, EarlyView.Abstract The global prevalence of obesity and related metabolic disorders has spurred interdisciplinary research to develop new intervention strategies. Current research is increasingly focusing on the exercise‐induced browning of white adipose tissue and the mechanisms by which it improves energy metabolism.
Yuhui Su +4 more
wiley +1 more source
Integrative physiology of skeletal muscle for maintaining cognitive health
The Journal of Physiology, EarlyView.Abstract figure legend Maintenance of brain/cognitive health and function is increasingly appreciated to be a systemic challenge. In particular, skeletal muscle influences the brain through release of myokines in response to contraction, which influence the expression of brain‐derived neurotrophic factor (BDNF) in the brain, a vital player in the ...
Matthew H. Brisendine, Joshua C. Drake
wiley +1 more source
Irisin, Turning Up the Heat [PDF]
Cell Metabolism, 2012 Exercise exerts beneficial effects on systemic metabolism. A recent Nature paper (Boström et al., 2012) identifies irisin as an exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin promotes brown adipocyte recruitment in white fat and improves systemic metabolism by increasing energy expenditure.
openaire +2 more sources
The central benefit of physiologically induced ketogenic states
The Journal of Physiology, EarlyView.Abstract figure legend This review describes the association between ketogenic states induced by physiological interventions such as fasting or aerobic exercise, exogenous ketone supply and ketogenic diets, as well as increased cognition through increased activity of brain‐derived neurotrophic factor (BDNF).
Antonia Giacco +6 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend A schematic diagram outlining the concept of enviromimetics, and the subclasses of exercise mimetics, epimimetics and cognitomimetics. The rationale is that environmental stimulation and lifestyle factors, including physical activity and cognitive stimulation, have shown beneficial effects across a range of human conditions ...
Anthony J. Hannan
wiley +1 more source
Role of irisin in bone diseases
Frontiers in Endocrinology, 2023 Bone diseases are common among middle-aged and elderly people, and harm to activities of daily living (ADL) and quality of life (QOL) for patients. It is crucial to search for key regulatory factors associated with the development of bone diseases and explore potential therapeutic targets for bone diseases.
Ruobing Zhao +5 more
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The Journal of Physiology, EarlyView.Abstract figure legend This study aimed to determine whether early sensorimotor restriction (SMR) alters mitochondrial enzyme activities in rat muscles and brain structures. SMR was induced via immobilizing the hind limbs of pups for 16 h per day during the dark phase from birth to postnatal day (PND) 28.
Mélanie Van Gaever +4 more
wiley +1 more source
Is Irisin an Anticarcinogenic Peptide?
Medicine Science | International Medical Journal, 2015 Prostate cancer is the most common type of cancer in males. There has been currently no therapy to cure various types of cancer, and hence, studies aiming to develop cancer treatment are important and have been ongoing. Irisin is a hormone, which regulates body weight and metabolism, including insulin resistance and is thought to have beneficial ...
Suat, Tekin +3 more
openaire +3 more sources