Results 71 to 80 of about 19,243 (300)
The Role of Interventional Irisin on Heart Molecular Physiology
Pharmaceuticals, 2022 Irisin, encoded by the FNDC5 (fibronectin type III domain containing 5) gene, is a novel myokine that has been implicated as an essential mediator of exercise benefits. Effects of irisin on heart physiology is still ambiguous.
Foad Alzoughool +5 more
doaj +1 more source
Irisin and FNDC5 in retrospect: An exercise hormone or a transmembrane receptor? [PDF]
, 2013 FNDC5 (fibronectin domain-containing [protein] 5) was initially discovered and characterized by two groups in 2002. In 2011 FNDC5 burst into prominence as the parent of irisin, a small protein containing the fibronectin type III domain.
Erickson, HP
core +1 more source
Irisin, in women and men: blood pressure, heart rate, obesity and insulin resistance
Frontiers in Endocrinology, 2023 Background Irisin is a myokine that increases with leisure time physical activity (LTPA) and for which a cardiovascular protective role has been postulated. Our aim was to assess this role in the general population. Methods A cross-sectional analysis was
D. Almeida González +5 more
semanticscholar +1 more source
The Role of Irisin in Alzheimer’s Disease [PDF]
Journal of Clinical Medicine, 2018 Alzheimer’s disease (AD) is characterized by progressive memory dysfunction, oxidative stress, and presence of senile plaques formed by amyloid beta (A β ) accumulation in the brain. AD is one of the most important causes of morbidity and mortality worldwide.
Oh Yoen Kim, Juhyun Song
openaire +3 more sources
Myokines in Acromegaly: An Altered Irisin Profile [PDF]
Frontiers in Endocrinology, 2021 IntroductionThe muscle is an endocrine organ controlling metabolic homeostasis. Irisin and myostatin are key myokines mediating this process. Acromegaly is a chronic disease with a wide spectrum of complications, including metabolic disturbances.PurposeTo examine the influence of acromegaly on irisin and myostatin secretion and their contribution to ...
Agnieszka Zembska +7 more
openaire +4 more sources
Cardiovascular DiabetologyBackground Diabetic cardiomyopathy (DCM) is a serious complication in patients with type 1 diabetes mellitus (T1DM), which still lacks adequate therapy.
Yuan-juan Tang +10 more
semanticscholar +1 more source
PLoS ONE, 2023 Recently, myocardial ischemia-reperfusion (I/R) injury was suggested associated with intestinal flora. However, irisin has demonstrated beneficial effects on myocardial I/R injury, thus increasing interest in exploring its mechanism.
Qingqing Liu +11 more
semanticscholar +1 more source
Irisin inhibits pancreatic cancer cell growth via the AMPK-mTOR pathway
Scientific Reports, 2018 Irisin, a recently identified myokine that is released from skeletal muscle following exercise, regulates body weight and influences various metabolic diseases such as obesity and diabetes.
Jiayu Liu +3 more
doaj +1 more source
Aging CellPostmenopausal osteoporosis is a prevalent metabolic bone disorder characterized by a decrease in bone mineral density and deterioration of bone microstructure. Despite the high prevalence of this disease, no effective treatment for osteoporosis has been
Lin Tao +7 more
semanticscholar +1 more source
Journal of Inflammation Research, 2023 Background PM2.5 exposure is one of the major inducements of various respiratory diseases and related mortality. Meanwhile, irisin, a metabolism and thermogenesis-related hormone, is found to be protective against acute lung injury induced by LPS, which ...
Jiao Ma +6 more
semanticscholar +1 more source