Results 21 to 30 of about 184,947,225 (237)

Dynamics of endogenous intoxication indicators in condition of acute blood loss complicated by ischemia-reperfusion of the limb, and their correction by carbacetam

Journal of Education, Health and Sport, 2020
Introduction. In the structure of injuries from gunshot wounds dominate the limb injuries that are often complicated by massive bleeding from the main vessels. The only means of rescue on the battlefield is a timely application of a tourniquet.
I. Strelbytska, A. Hudyma
doaj   +1 more source

Randomized preclinical study of machine perfusion in vascularized composite allografts

BJS (British Journal of Surgery), EarlyView., 2020
This study was designed to identify the optimum machine perfusion parameters for preservation of limbs before transplantation, and determine whether this was better than cold storage. Normothermic machine perfusion at a pressure of 70 mmHg (NMP‐70) provided superior preservation to cold storage after transplantation.
K. R. Amin, J. P. Stone, J. Kerr, A. Geraghty, L. Joseph, A. Montero‐Fernandez, J. K. Wong, J. E. Fildes   +7 more
wiley   +1 more source

Renoprotective effect of edaravone in acute limb ischemia/reperfusion injury

The Turkish Journal of Thoracic and Cardiovascular Surgery, 2020
In this experimental study, we aimed to investigate the efficacy of edaravone on renal injury due to acute lower limb ischemia/reperfusion in a rat model.Between June 2015 and August 2015, a total of 40 male Wistar rats were used in this study. The rats were randomly divided into the sham, ischemia/reperfusion, edaravone, and solvent groups (n=10 in ...
İlker, İnce, İlker, Akar, Akgül, Arıcı   +2 more
openaire   +3 more sources

A novel laser-doppler flowmetry assisted murine model of acute hindlimb ischemia-reperfusion for free flap research [PDF]

, 2013
Suitable and reproducible experimental models of translational research in reconstructive surgery that allow in-vivo investigation of diverse molecular and cellular mechanisms are still limited.
Isabella Kanzler, Matthias Knobe, Christoph Jan Wruck, Frank Hölzle, Brandacher, Gerald, Nancy Tuchscheerer, David Mitchell, Athanassios Fragoulis, Hölzle, Frank, Kanatas, Anastasios, Mitchell, David, Wruck, Christoph Jan, Othman Al-Sawaf, René Tolba, Knobe, Matthias, Tohidnezhad, Mersedeh, Elisa Anamaria Liehn, Liehn, Elisa Anamaria, Sönmez, Tolga Taha, Anastasios Kanatas, Thomas Pufe, Pufe, Thomas, Al-Sawaf, Othman, Kanzler, Isabella, Tolga Taha Sönmez, Tolba, René H., Fragoulis, Athanassios, Mitchell, David A., Tuchscheerer, Nancy, Gerald Brandacher, Mersedeh Tohidnezhad, Tohidnezhad Mersedeh, Knobe Matthias, Fragoulis Athanassios, Pufe Thomas, Hölzle Frank, Tuchscheerer Nancy, Wruck Christoph Jan, Tolba René, Al-Sawaf Othman, Liehn Elisa Anamaria, Brandacher Gerald, Kanatas Anastasios, Sönmez Tolga Taha, Kanzler Isabella, Mitchell David   +45 more
core   +1 more source

Comparison of remote and local postconditioning against hepatic ischemic-reperfusion injury in rats [PDF]

Acta Cirúrgica Brasileira, 2021
Purpose: The aim of this study is to compare the hepatic protective effect of both remote and local postconditioning (POS). Methods: Twenty-eight Wistar rats were assigned into four groups: sham group(SHAM), ischemia-reperfusion group (IR), local ...
Edson Yuzur Yasojima, Robson José de Souza Domingues, Renata Cunha Silva, Luis Fernando Freitas de Sousa, Sérgio Cunha Trindade Júnior   +4 more
doaj   +1 more source

Transient limb ischemia induces remote ischemic preconditioning in vivo [PDF]

, 2002
Background-Ischemic preconditioning reduces local tissue injury caused by subsequent ischemia-reperfusion (IR), but may also have a salutary effect on IR injury of tissues remote from those undergoing preconditioning.
Hoschtitzky, JA, Sorensen, K, Redington, AN, Mortensen, UM, Kristiansen, SB, Kharbanda, RK, Vogel, M, White, PA, Schmidt, MR, MacAllister, R   +9 more
core   +1 more source

Protective Effects of Dexmedetomidine and Oxycodone in Patients Undergoing Limb Ischemia-Reperfusion [PDF]

Medical Science Monitor, 2019
BACKGROUND Tourniquet-related complications are a common clinical problem. In the present study, we compared the effects of dexmedetomidine vs. oxycodone in patients undergoing limb ischemia-reperfusion. MATERIAL AND METHODS Fifty-four patients undergoing unilateral lower-extremity surgery under combined spinal and epidural anesthesia were randomly ...
Cheng, Wenjie, Wang, Mingjie, Liu, Peng, Zhao, Shuang, Liu, Xin, Wang, Xiuli   +5 more
openaire   +2 more sources

Effects of dexmedetomidine in conjunction with remote ischemic preconditioning on renal ischemia–reperfusion injury in rats

Revista Brasileira de Anestesiologia, 2014
Background and objectives: The aim of this study was to evaluate the effects of remote ischemic preconditioning by brief ischemia of unilateral hind limb when combined with dexmedetomidine on renal ischemia-reperfusion injury by histopathology and active
Emine Bagcik, Sevda Ozkardesler, Nilay Boztas, Bekir Ugur Ergur, Mert Akan, Mehmet Guneli, Sule Ozbilgin   +6 more
doaj   +1 more source

Application of a novel method for subsequent evaluation of sinusoids and postsinusoidal venules after ischemia-reperfusion injury of rat liver [PDF]

, 1998
Although several intravital fluorescence microscopic studies demonstrated that microcirculatory derangement is induced during liver ischemia-reperfusion, these data were obtained from randomly selected microvascular areas and microvessels, Repeated ...
Todoroki, T., Schildberg, Friedrich Wilhelm, Kondo, Tadashi, Okamoto, S., Messmer, K., Hirano, T.   +5 more
core   +1 more source

Lipid emulsion mitigates impaired pulmonary function induced by limb ischemia/reperfusion in rats through attenuation of local cellular injury and the subsequent systemic inflammatory

BMC Anesthesiology, 2017
Background Limb ischemia/reperfusion causes inflammation and elicits oxidative stress that may lead to local tissue damage and remote organ such as lung injury. This study investigates pulmonary function after limb ischemia/reperfusion and the protective
Fangfang Xia, Yun Xia, Sisi Chen, Lulu Chen, Weijuan Zhu, Yuanqing Chen, Thomas J. Papadimos, Xuzhong Xu, Le Liu   +8 more
doaj   +1 more source