Results 31 to 40 of about 184,947,225 (237)

Tumor Necrosis Factor-α Contributes to Ischemia- and Reperfusion-Induced Endothelial Activation in Isolated Hearts [PDF]

open access: yes, 1999
During myocardial reperfusion, polymorphonuclear neutrophil (PMN) adhesion involving the intercellular adhesion molecule-1 (ICAM-1) may lead to aggravation and prolongation of reperfusion injury.
Kelly, Ralph A.   +15 more
core   +1 more source

The protective effect of cilostazol on isolated rabbit femoral arteries under conditions of ischemia and reperfusion: the role of the nitric oxide pathway

open access: yesClinics, 2012
OBJECTIVES: The clinical significance of ischemia/reperfusion of the lower extremities demands further investigation to enable the development of more effective therapeutic alternatives.
Mariana R.G.A. Santos   +5 more
doaj   +1 more source

Caffeine Mitigates Lung Inflammation Induced by Ischemia‐Reperfusion of Lower Limbs in Rats [PDF]

open access: yesMediators of Inflammation, 2015
Reperfusion of ischemic limbs can induce inflammation and subsequently cause acute lung injury. Caffeine, a widely used psychostimulant, possesses potent anti‐inflammatory capacity. We elucidated whether caffeine can mitigate lung inflammation caused by ischemia‐reperfusion (IR) of the lower limbs. Adult male Sprague‐Dawley rats were randomly allocated
Wei-Chi Chou   +4 more
openaire   +3 more sources

Involvement of Nitric Oxide in Microcirculatory Reactions after Ischemia-Reperfusion of the Rat Urinary Bladder [PDF]

open access: yes, 2009
Background: Nitric oxide ( NO) plays a role in inflammation. Our aim was to investigate the role of NO in the microcirculatory changes after ischemia-reperfusion (I/R) of the bladder using intravital videomicroscopy (IVM).
Bajory, Z.   +9 more
core   +1 more source

Pulmonary Morphological Changes in the Simulation and Treatment of Lower Limb Ischemic and Perfusion Lesions

open access: yesОбщая реаниматология, 2006
Objective: to investigate pulmonary morphological changes in animals with limb ischemic and reperfusion lesions, which were treated with hemocarboperfusion on sodium hypochlorite-modified sorbents.Materials and methods. The investigation was conducted on
V. I. Sergiyenko   +3 more
doaj   +1 more source

Phosphorylation of Vasodilator-Stimulated Phosphoprotein (VASP) dampens hepatic ischemia-reperfusion injury [PDF]

open access: yes, 2011
Recent work has demonstrated that the formation of platelet neutrophil complexes (PNCs) affects inflammatory tissue injury. Vasodilator-stimulated phosphoprotein (VASP) is crucially involved into the control of PNC formation and myocardial reperfusion ...
Birk, Philipp   +20 more
core   +2 more sources

Gangrene, revascularization, and limb function improved with E-selectin/adeno-associated virus gene therapy

open access: yesJVS - Vascular Science, 2021
Objective: Novel therapeutic angiogenic concepts for critical limb ischemia are still needed for limb salvage. E-selectin, a cell-adhesion molecule, is vital for recruitment of the stem/progenitor cells necessary for neovascularization in ischemic ...
Hallie J. Quiroz, MD   +9 more
doaj   +1 more source

Protective Role of Progesterone on Lung Injury Induced by Ischemia Reperfusion of the Lower Limbs

open access: yesSouthern Clinics of Istanbul Eurasia, 2022
Objective: Remote lung injury is one of the most challenging issues in patients undergoing ischemia reperfusion (IR) injury of the lower limbs. We examined the role of progesterone (PG) on the remote injury of the lungs seen after IR of the lower limbs. Methods: Eighteen male Sprague Dawley rats were divided into three groups.
AK, ESİN   +3 more
openaire   +1 more source

Significance of lipid peroxidation processes in renal excretory dysfunction in cases of acute blood loss complicated by limb ischemia-reperfusion and its correction

open access: yesJournal of Education, Health and Sport, 2019
Introduction. Activation of lipid peroxidation processes, which are exacerbated in cases of limb ischemia-reperfusion associated with temporary application of a tourniquetis a key mechanism of acute blood loss.
V. V. Shatskyi, A. A. Hudyma
doaj   +1 more source

Natriuretic peptide receptor-C regulates coronary blood flow and prevents myocardial ischemia/reperfusion injury: novel cardioprotective role for endothelium-derived C-type natriuretic peptide [PDF]

open access: yes, 2004
Background: Ischemia/reperfusion (I/R) injury complicates myocardial infarction and stroke by exacerbating tissue damage and increasing risk of mortality.
Ramona Scotl   +15 more
core   +1 more source

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