Results 211 to 220 of about 47,870 (244)

Islet Amyloid, Islet-Amyloid Polypeptide, and Diabetes Mellitus

New England Journal of Medicine, 1989
Islet-amyloid deposits, which are a common feature of Type II diabetes mellitus, are derived from the polymerization of a putative hormone identified as IAPP. IAPP is synthesized by normal islet beta cells and probably is cosecreted with insulin. Although the physiologic function of IAPP and its role in the pathogenesis of Type II diabetes mellitus are
Franklin H. Epstein, Kenneth H. Johnson, Timothy D. O'Brien, Christer Betsholtz, Per Westermark   +4 more
openaire   +2 more sources

Critical islet mass for successful porcine islet autotrasplantation

Journal of Molecular Medicine, 1999
A major reason for the failure of clinical islet transplantations may be a limited islet mass. The aim of this study was to determine the critical islet mass necessary for normalization of glucose metabolism in a porcine model. Diabetes was induced by total pancreatectomy.
J, Mellert, B J, Hering, X, Liu, D, Brandhorst, H, Brandhorst, F, Pfeffer, K, Federlin, R G, Bretzel, U T, Hopt   +8 more
openaire   +2 more sources

Islet-Derived Progenitors as a Source of In Vitro Islet Regeneration

2009
Current therapies do not prevent the complications of diabetes. Furthermore, these therapies do not address the underlying pathology; the lack of functional beta-cell mass that occurs in both types 1 and 2 diabetes. While pancreas and islet transplantation do serve to increase beta-cell mass, a lack of donor organs limits the therapeutic potential of ...
Stephen, Hanley, Lawrence, Rosenberg
openaire   +2 more sources

Isletism

The first chapter explores “Isletism,” the ideology that underpins the ongoing assault on Pacific peoples. For centuries, Westerners have seen the Pacific Islands as isolated islets outside modern history. Imagining the tropical Island as marooned at the earliest stage of a supposedly unilinear path to “progress,” Western narratives have denied ...
openaire   +1 more source

Islet Transplantation

2003
Berney, Thierry, Kenyon, N.S., Alejandro, R., Inverardi, L., Mintz, D.H., Ricordi, C.   +5 more
openaire   +2 more sources

Islet Transplantation

1997
G S, Korbutt, G L, Warlock, R V, Rajotte
openaire   +2 more sources

Islet transplantation

Diabetic Medicine, 2001
openaire   +3 more sources

Altered islet prohormone processing: a cause or consequence of diabetes?

Physiological Reviews, 2022
Timothy Kieffer
exaly  

Islet Transplantation

New England Journal of Medicine, 2007
openaire   +2 more sources

ISLET ALONE, ISLET-KIDNEY, AND ISLET AFTER- KIDNEY TRANSPLANTATION IN ARGENTINA

Transplantation, 2008
S Hyon, M Barbich, R Groppa, L Gimeno, L Grosembacher, P Martinez, R Marenchino, N Imperiali, L Algranati, P Argibay   +9 more
openaire   +1 more source