Results 131 to 140 of about 13,872 (224)

Chromosome‐Level Genome Assembly of the Allotetraploid Gynostemma pentaphyllum Provides Novel Insights Into the Biosynthesis of Ginsenoside and Gypenoside LVI

Plant Biotechnology Journal, Volume 24, Issue 6, Page 4204-4220, June 2026.
ABSTRACT Gynostemma pentaphyllum, a herb used in tea and traditional Chinese medicine, shows geographic variation in its production of valuable dammarane‐type ginsenosides and gypenoside LVI between populations from Suining (SN) and Nanning (NN). To elucidate the mechanisms underlying this differential metabolite accumulation, a chromosome‐level genome
Peina Zhou, Si‐Jie Liu, Lijin Huang, Yingping Wang, Xinyu Jiang, Wang Dong, Jianfeng Gong, Long Wang, Yuyin Zhao, Huiying Wang, Ping Li, Jia‐Yu Xue, Xu Lu   +12 more
wiley   +1 more source

Inhibitors of the Nonmevalonate Pathway of Isoprenoid Biosynthesis as Antimalarial Drugs

, 1999
A mevalonate-independent pathway of isoprenoid biosynthesis present in Plasmodium falciparum was shown to represent an effective target for chemotherapy of malaria. This pathway includes 1-deoxy- d
Eberl, Matthias, Jomaa, H., Beck, E., Boran Altincicek, Dominique Soldati, Silke Sanderbrand, Ivana Türbachova, Claus Weidemeyer, Sanderbrand, S., Altincicek, B., Lichtenthalter, H. K., Weidemeyer, C., Hintz, M., Turbachova, I., Jochen Wiesner, Ewald Beck, Wiesner, J., Hassan Jomaa, Martin Hintz, Zeidler, J., Hartmut K. Lichtenthaler, Johannes Zeidler, Soldati, D., Matthias Eberl   +23 more
core   +1 more source

Quantification of Plant Resistance to Isoprenoid Biosynthesis Inhibitors

, 2014
Plants use two pathways for the production of the same universal isoprenoid precursors: the mevalonic acid (MVA) pathway and the methylerythritol 4-phosphate (MEP) pathway. Inhibitors of the MVA pathway prevent the activity of the shoot apical meristem and the development of true leaves in seedlings, whereas those inhibiting the MEP pathway show an ...
Perello, Catalina, Rodríguez-Concepción, Manuel, Pulido, Pablo   +2 more
openaire   +3 more sources

Cross‐Species Reprogramming of Developmental Plasticity and Metabolic Rewiring via Banana‐Derived WUS2 Developmental Regulator

Plant Biotechnology Journal, Volume 24, Issue 6, Page 4174-4189, June 2026.
ABSTRACT Plant regeneration is governed by intrinsic gene regulation and phytohormonal cues. WUSCHEL (WUS) gene promotes regeneration, but its broader functional role remains unexplored. Here, we demonstrate that the constitutive and inducible expression of banana‐derived WUS2 (GN‐WUS2) enhances regeneration in Nicotiana tabacum (tobacco) and Musa ...
Roni Chaudhary, Surender Singh, Usman Ali, Siddharth Tiwari   +3 more
wiley   +1 more source

Fosmidomycin for the Treatment of Canine Otitis Externa: A Randomised, Double‐Blinded, Controlled ‘Split Body’ Clinical Trial

Veterinary Dermatology, Volume 37, Issue 3, Page 427-436, June 2026.
ABSTRACT Background Targeted antimicrobial therapy for canine otitis externa (OE) represents an opportunity for antimicrobial stewardship. Fosmidomycin selectively inhibits the non‐mevalonate pathway for isoprenoid biosynthesis utilised by canine‐adapted, and not human‐adapted, staphylococci.
Lindsey E. Citron, Darko Stefanovski, Youwen You, Rachel Proctor, Donna Watson, Julie Randall, Christine L. Cain   +6 more
wiley   +1 more source

Kinetic and structural studies on the first three enzymes in Bacillus anthracis isoprenoid biosynthesis.

, 2008
Kinetic and structural studies on the first three enzymes in Bacillus anthracis isoprenoid ...
Patrick Stanley. Miller (7999745)
core  

A RubisCO-like protein links SAM metabolism with isoprenoid biosynthesis

, 2012
Functional assignment of uncharacterized proteins is a challenge in the era of large-scale genome sequencing. Here, we combine in extracto NMR, proteomics and transcriptomics with a newly developed (knock-out) metabolomics platform to determine a ...
Evans, B., Wood, B., Warlick, B., Sriram, J., Cho, K., Tabita, F., Erb, T., Imker, H., Sweedler, J., Gerlt, J.   +9 more
core   +1 more source

Studies on isoprenoid biosynthesis in Euglena gracilis

This dissertation describes studies of isoprenoid biosynthesis in the phytoflagellate Euglena gracilis. Elucidation of a novel isoprerioid pathway, the 2-Cmethyl-D-erythritol-4-phosphate (MEP) pathway, in addition to the generally known mevalonate (MVA ...
Kim, Dojung
core  

Terpene and isoprenoid biosynthesis in Cannabis sativa

, 2020
Cannabis sativa (cannabis, marijuana, hemp) is a plant species grown widely for its psychoactive and medicinal properties. Cannabis products were made illegal in most of the world in the early 1900s, but regulations have recently been relaxed or lifted ...
Booth, Judith
core  

The methylerythritol phosphate pathway for isoprenoid biosynthesis in coccidia: Presence and sensitivity to fosmidomycin

, 2007
International audienceThe apicoplast is a recently discovered, plastid-like organelle present in most apicomplexa. The methylerythritol phosphate (MEP) pathway involved in isoprenoid biosynthesis is one of the metabolic pathways associated with the ...
Goubard, Armelle, Mincheva, Zoia, Armelle Goubard, Bout, Daniel, Florence Velge-Roussel, Rideau, Marc, Zoia Mincheva, Marc Clastre, Marc Rideau, Fabrice Laurent, Anne Prel, Daniel Bout, Laurent, Fabrice, Velge-Roussel, Florence, Clastre, Marc, Prel, Anne, Viaud-Massuart, Marie-Claude, Marie-Claude Viaud-Massuart   +17 more
core   +1 more source