Results 121 to 130 of about 22,403 (243)

A Novel Dual‐Target Compound Designed With Potent Herbicidal and Fungicidal Activity Inspired by Conserved Phytoene Synthase Domains

Plant Biotechnology Journal, Volume 24, Issue 5, Page 2903-2913, May 2026.
ABSTRACT The development of dual‐target inhibitors represents a cost‐effective strategy for integrated pest management. Here, we report the first dual‐target inhibitors designed against the evolutionarily conserved domain of phytoene synthase (PSY), a key enzyme in carotenoid biosynthesis.
Di Zhang, Liang Li, Chunxue Wang, Nuo Zhou, Zhilei Yu, Tianyi Shen, Baifan Wang, Qiang Bian, Dejun Ma, Yucheng Gu, Han Xu, Zhen Xi   +11 more
wiley   +1 more source

Three Closely Related Spodoptera Species Similarly Affect Gene Expression and Phytohormone Levels but Differentially Induce Volatile Emissions in Maize

Plant, Cell &Environment, Volume 49, Issue 5, Page 2394-2412, May 2026.
ABSTRACT Plants can perceive specific elicitors in the oral secretions (OS) of herbivorous insects and respond by increasing their defences. Whether plants can discriminate among similar herbivorous insect species and differentially modulate their defence responses against them is largely unknown.
Wenfeng Ye, Sara Leite Dias, Marine Mamin, Carla C. M. Arce, Ted C. J. Turlings   +4 more
wiley   +1 more source

Integrative Transcriptomic and Target Metabolite Analysis as a New Tool for Designing Metabolic Engineering in Yeast

Biomolecules
Precision fermentation processes, especially when using edited microorganisms, demand accuracy in the bioengineering process to maximize the desired outcome and to avoid adverse effects.
Alejandro Lopez-Barbera, Nerea Abasolo, Helena Torrell, Nuria Canela, Salvador Fernández-Arroyo   +4 more
doaj   +1 more source

Prenylcysteine Oxidase 1 Deficiency Protects the Cardiac Muscle Cell Line HL‐1 Against Ischaemic/Hypoxic Stress

The FASEB Journal, Volume 40, Issue 8, 30 April 2026.
Ischaemic/hypoxic stress leads to heart remodeling and dysfunction. PCYOX1 promotes cardiomyocyte survival during injury, reducing the generation of reactive oxygen species. PCYOX1 deficiency regulates key proteins to preserve cardiomyocyte structure and function such as creatine kinase.
Cristina Banfi, Lisa Brocca, Alice Bascucci, Giulia Giusy Papaianni, Alice Mallia, Sonia Eligini   +5 more
wiley   +1 more source

BPM31510 Increases the CoQ Pool in Chemically Induced CoQ‐Deficient Cells, CoQ‐Deficient Patient Fibroblasts, and in Metabolically Active Murine Tissues

The FASEB Journal, Volume 40, Issue 7, 15 April 2026.
Graphical abstract illustrating the in vitro and in vivo experimental workflow used to compare BPM31510, a nanoliposomal formulation of oxidized CoQ10, with conventional CoQ10. Chemically induced CoQ‐deficient SH‐SY5Y cells, CoQ‐deficient patient fibroblasts, and C57BL/6J mice receiving oral CoQ10 or intraperitoneal BPM31510 were subjected to plasma ...
Juan J. Aristizabal‐Henao, Sarah R. Wessel, Sylwia A. Stopka, Srada Karmacharya, Devon Van Cura, Alba Pesini, Kelsey R. Nickerson, Kashni Grover, Oksana Zavidij, Archna Ravi, Andressa L. Mota, Kenneth M. Rosen, Maria‐Dorothea Nastke, Megan K. Cox, Niven R. Narain, Vijay Modur, Catarina M. Quinzii, Stephane Gesta, Michael A. Kiebish   +18 more
wiley   +1 more source

Glucose 6‐phosphate dehydrogenase variants increase NADPH pools for yeast isoprenoid production

FEBS Open Bio
Isoprenoid biosynthesis has a significant requirement for the co‐factor NADPH. Thus, increasing NADPH levels for enhancing isoprenoid yields in synthetic biology is critical.
Sri Harsha Adusumilli, Anuthariq Alikkam Veetil, Chinmayee Choudhury, Banani Chattopadhyaya, Diptimayee Behera, Anand Kumar Bachhawat   +5 more
doaj   +1 more source

Plant Isoprenoids: A General Overview

, 2014
Borderline personality disorder (BPD) was first described 75 years ago (Stern, 1938), but only became accepted in the classification of mental disorders decades later (American Psychiatric Association, 1980); but it was at that point that research on the disorder took off.
openaire   +3 more sources

Harnessing evolution: leveraging bacterial isoprenoid pathway diversity toward improved bioengineering strategies. [PDF]

J Bacteriol
Qabar CM, Marshall BA, Landick R, Cox JS.   +3 more
europepmc   +1 more source

Massive wildfires followed oceanic anoxic events during the Late Devonian Frasnian-Famennian mass extinction. [PDF]

Sci Adv
Lu M, Sun Y, Duan G, Ikejiri T, Liu N, Luo Q, Lv D, Carroll R, Lu Y.   +8 more
europepmc   +1 more source

Comparative Phytochemical Analysis of Five Species of the Genus <i>Arthrophytum</i> Schrenk (Amaranthaceae) from the Flora of Kazakhstan. [PDF]

Metabolites
Ussen S, Vesselova PV, Kudabayeva GM, Sergazina MM, Alimzhanova MB.   +4 more
europepmc   +1 more source