Results 11 to 20 of about 16,389 (298)

Isothiocyanates: a review [PDF]

Research Journal of Pharmacognosy, 2018
Isothiocyanates (ITCs) are naturally occurring molecules belonging to highly reactive organosulphur synthons, with the general structure R–N=C=S. The precursor molecule glucosinolate anions are hydrolyzed enzymatically (under the effect of myrosinase ...
Chandra Kala*, Syed Salman Ali, Nabeel Ahmad, Sadaf Jamal Gilani, Najam Ali Khan   +4 more
doaj   +1 more source

Current Methods for the Extraction and Analysis of Isothiocyanates and Indoles in Cruciferous Vegetables

Analytica, 2021
Cruciferous vegetables are characterized by the presence of sulfur-containing secondary plant metabolites known as glucosinolates (GLS). The consumption of cruciferous vegetables such as broccoli, cabbage, rocket salad, and cauliflower has been related ...
Sofia Karanikolopoulou, Panagiota-Kyriaki Revelou, Marinos Xagoraris, Maroula G. Kokotou, Violetta Constantinou-Kokotou   +4 more
doaj   +1 more source

Glucosinolates and Isothiocyantes in Processed Rapeseed Determined by HPLC-DAD-qTOF

Plants, 2021
Glucosinolates are well known as natural antimicrobials and anticarcinogenic agents. However, these compounds can lose their properties and transform into antinutrients, depending on processing conditions.
Ana Miklavčič Višnjevec, Angelica Tamayo Tenorio, Anne Christine Steenkjær Hastrup, Natanya Majbritt Louie Hansen, Kelly Peeters, Matthew Schwarzkopf   +5 more
doaj   +1 more source

Chemical Priming by Isothiocyanates Protects Against Intoxication by Products of the Mustard Oil Bomb

Frontiers in Plant Science, 2020
In Brassicaceae, tissue damage triggers the mustard oil bomb i.e., activates the degradation of glucosinolates by myrosinases leading to a rapid accumulation of isothiocyanates at the site of damage.
Elena Ferber, Julian Gerhards, Miriam Sauer, Markus Krischke, Marcus T. Dittrich, Marcus T. Dittrich, Tobias Müller, Susanne Berger, Agnes Fekete, Martin J. Mueller   +9 more
doaj   +1 more source

Assessment of Methodological Pipelines for the Determination of Isothiocyanates Derived from Natural Sources

Antioxidants, 2022
Isothiocyanates are biologically active secondary metabolites liberated via enzymatic hydrolysis of their sulfur enriched precursors, glucosinolates, upon tissue plant disruption. The importance of this class of compounds lies in their capacity to induce
Sotiris Kyriakou, Dimitrios T. Trafalis, Maria V. Deligiorgi, Rodrigo Franco, Aglaia Pappa, Mihalis I. Panayiotidis   +5 more
doaj   +1 more source

Cooking Methods for Preserving Isothiocyanates and Reducing Goitrin in Brassica Vegetables

Foods, 2023
Glucosinolates in Brassica vegetables can be hydrolyzed into various products, e.g., chemopreventive agents, isothiocyanates (ITCs) and anti-thyroid substance, goitrin. Cooking can reduce goitrin but destroy isothiocyanates.
Thanaporn Panduang, Pakkapong Phucharoenrak, Weeraya Karnpanit, Dunyaporn Trachootham   +3 more
doaj   +1 more source

Anti-tumor activity and signaling events triggered by the isothiocyanates, sulforaphane and phenethyl isothiocyanate, in multiple myeloma

Haematologica, 2011
Background Isothiocyanates, a family of phytochemicals found in cruciferous vegetables, have cytotoxic effects against several types of tumor cells. Multiple myeloma is a fatal disease characterized by clonal proliferation of plasma cells in the bone ...
Jana Jakubikova, David Cervi, Melissa Ooi, Kihyun Kim, Sabikun Nahar, Steffen Klippel, Dana Cholujova, Merav Leiba, John F. Daley, Jake Delmore, Joseph Negri, Simona Blotta, Douglas W. McMillin, Teru Hideshima, Paul G. Richardson, Jan Sedlak, Kenneth C. Anderson, Constantine S. Mitsiades   +17 more
doaj   +1 more source

Glucosinolates From Cruciferous Vegetables and Their Potential Role in Chronic Disease: Investigating the Preclinical and Clinical Evidence

Frontiers in Pharmacology, 2021
An increasing body of evidence highlights the strong potential for a diet rich in fruit and vegetables to delay, and often prevent, the onset of chronic diseases, including cardiometabolic, neurological, and musculoskeletal conditions, and certain ...
Emma L. Connolly, Marc Sim, Marc Sim, Nikolaj Travica, Wolfgang Marx, Gemma Beasy, Gordon S. Lynch, Catherine P. Bondonno, Catherine P. Bondonno, Joshua R. Lewis, Joshua R. Lewis, Joshua R. Lewis, Jonathan M. Hodgson, Jonathan M. Hodgson, Lauren C. Blekkenhorst, Lauren C. Blekkenhorst   +15 more
doaj   +1 more source

Myrosinase-dependent and –independent formation and control of isothiocyanate products of glucosinolate hydrolysis.

Frontiers in Plant Science, 2015
Brassicales contain a myrosinase enzyme that hydrolyzes glucosinolates to form toxic isothiocyanates, as a defense against bacteria, fungi, insects and herbivores including man.
Donato eAngelino, Edward B Dosz, Jianghao eSun, Jennifer L Hoeflinger, Maxwell L Van Tassell, Pei eChen, James M Harnly, Michael J Miller, Elizabeth H Jeffery   +8 more
doaj   +1 more source

A Lesson Learnt from Food Chemistry—Elevated Temperature Triggers the Antioxidant Action of Two Edible Isothiocyanates: Erucin and Sulforaphane

Antioxidants, 2020
In this communication we demonstrate that two natural isothiocyanates, sulforaphane (SFN) and erucin (ERN), inhibit autoxidation of lipids at 140 °C but not below 100 °C.
Jakub Cedrowski, Kajetan Dąbrowa, Agnieszka Krogul-Sobczak, Grzegorz Litwinienko   +3 more
doaj   +1 more source