Results 31 to 40 of about 19,561 (308)

Recent advances in metal catalyzed or mediated cyclization/functionalization of alkynes to construct isoxazoles

open access: yes, 2020
Isoxazoles and their derivatives represent privileged heteroaromatic motifs, which exhibit remarkable biological and pharmaceutical activities. Notably, metal catalyzed or mediated cyclization/functionalization of alkynes such as alkynone oxime ethers ...
Jianxiao Li   +3 more
semanticscholar   +1 more source

Gold(I)-catalyzed synthesis of 3-sulfenyl pyrroles and indoles by a regioselective annulation of alkynyl thioethers [PDF]

open access: yes, 2021
[Image: see text] The combination of nucleophilic nitrenoids and π-acid catalysis has emerged as a powerful tool in heterocycle synthesis. Accessing more varied heterocycle-substitution patterns by maintaining the same reaction pathways across different ...
Davies, Paul   +3 more
core   +1 more source

Isoxazolium N-ylides and 1-oxa-5-azahexa-1,3,5-trienes on the way from isoxazoles to 2H-1,3-oxazines

open access: yesBeilstein Journal of Organic Chemistry, 2014
Theoretical and experimental studies of the reaction of isoxazoles with diazo compounds show that the formation of 2H-1,3-oxazines proceeds via the formation of (3Z)-1-oxa-5-azahexa-1,3,5-trienes which undergo a 6π-cyclization.
Alexander F. Khlebnikov   +6 more
doaj   +1 more source

A low-toxicity method for the separation of lanosterol and dihydrolanosterol from commercial mixtures [PDF]

open access: yes, 2004
We describe an inexpensive, low-toxicity and high-yielding method for the production of pure lanosterol and dihydrolanosterol from the commercially available mixture.
Kavtaradze, Levan K.   +2 more
core   +2 more sources

Polarclean as a Sustainable Reaction Medium for the Waste Minimized Synthesis of Heterocyclic Compounds

open access: yesFrontiers in Chemistry, 2019
Herein we report the use of Rhodiasolv© Polarclean as a novel polar aprotic solvent for the synthesis of decorated heterocycles via dipolar cycloaddition (isooxazoles) or intramolecular C–H functionalization processes (benzo-fused chromenes).
Francesco Ferlin   +6 more
doaj   +1 more source

Synthesis and biological evaluation of ferrocene-based cannabinoid receptor 2 ligands [PDF]

open access: yes, 2018
Ferrocene analogues of known fatty acid amide hydrolase inhibitors and CB2 ligands have been synthesized and characterized spectroscopically and crystallographically.
Barczyk, Amélie   +11 more
core   +2 more sources

Ruthenium-catalyzed asymmetric reduction of isoxazolium salts : access to optically active Δ4-isoxazolines [PDF]

open access: yes, 2018
A tethered MsDPEN–ruthenium catalyst reduces a series of isoxazolium salts, affording optically active Δ4-isoxazolines in moderate to good yields and enantioenrichment. The redundancy of heating or high pressures allowed for chemoselective reduction with
Chew, Renta Jonathan, Wills, Martin
core   +1 more source

Various Synthetic Pathways for the Synthesis of 3,4-Disubstituted Isoxazole by One Pot Multicomponent Reaction

open access: yesOrbital: The Electronic Journal of Chemistry, 2020
Isoxazole is a five membered heterocyclic compound which is an azole with an oxygen atom next to nitrogen. The substituted isoxazole derivatives show various biological activities like antimicrobial, antiviral, anti-inflammatory, antioxidant, anticancer ...
Parul Setia, Ruchi Bharti, Renu Sharma
doaj   +3 more sources

Synthesis of Some Fused Pyrazoles and Isoxazoles

open access: yesMolecules, 2000
The α-keto methylene group in 3,5-diaryl-2-cyclohexenones 2 and 3,5-diarylcyclohexanones 8 have been used to obtain fused pyrazoles and isoxazoles. The new compounds were characterized by IR and 1H-NMR spectral data.
Dandu Bhaskar Reddy   +4 more
doaj   +1 more source

5-Chloroisoxazoles: A Versatile Starting Material for the Preparation of Amides, Anhydrides, Esters, and Thioesters of 2H-Azirine-2-carboxylic Acids

open access: yesMolecules, 2022
Amides, anhydrides, esters, and thioesters of 2H-azirine-2-carboxylic acids were prepared by a rapid procedure at room temperature involving FeCl2-catalyzed isomerization of 5-chloroisoxazoles to 2H-azirine-2-carbonyl chlorides, followed by reaction with
Anastasiya V. Agafonova   +2 more
doaj   +1 more source

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