Results 31 to 40 of about 19,561 (308)
Isoxazoles and their derivatives represent privileged heteroaromatic motifs, which exhibit remarkable biological and pharmaceutical activities. Notably, metal catalyzed or mediated cyclization/functionalization of alkynes such as alkynone oxime ethers ...
Jianxiao Li+3 more
semanticscholar +1 more source
Gold(I)-catalyzed synthesis of 3-sulfenyl pyrroles and indoles by a regioselective annulation of alkynyl thioethers [PDF]
[Image: see text] The combination of nucleophilic nitrenoids and π-acid catalysis has emerged as a powerful tool in heterocycle synthesis. Accessing more varied heterocycle-substitution patterns by maintaining the same reaction pathways across different ...
Davies, Paul+3 more
core +1 more source
Isoxazolium N-ylides and 1-oxa-5-azahexa-1,3,5-trienes on the way from isoxazoles to 2H-1,3-oxazines
Theoretical and experimental studies of the reaction of isoxazoles with diazo compounds show that the formation of 2H-1,3-oxazines proceeds via the formation of (3Z)-1-oxa-5-azahexa-1,3,5-trienes which undergo a 6π-cyclization.
Alexander F. Khlebnikov+6 more
doaj +1 more source
A low-toxicity method for the separation of lanosterol and dihydrolanosterol from commercial mixtures [PDF]
We describe an inexpensive, low-toxicity and high-yielding method for the production of pure lanosterol and dihydrolanosterol from the commercially available mixture.
Kavtaradze, Levan K.+2 more
core +2 more sources
Herein we report the use of Rhodiasolv© Polarclean as a novel polar aprotic solvent for the synthesis of decorated heterocycles via dipolar cycloaddition (isooxazoles) or intramolecular C–H functionalization processes (benzo-fused chromenes).
Francesco Ferlin+6 more
doaj +1 more source
Synthesis and biological evaluation of ferrocene-based cannabinoid receptor 2 ligands [PDF]
Ferrocene analogues of known fatty acid amide hydrolase inhibitors and CB2 ligands have been synthesized and characterized spectroscopically and crystallographically.
Barczyk, Amélie+11 more
core +2 more sources
Ruthenium-catalyzed asymmetric reduction of isoxazolium salts : access to optically active Δ4-isoxazolines [PDF]
A tethered MsDPEN–ruthenium catalyst reduces a series of isoxazolium salts, affording optically active Δ4-isoxazolines in moderate to good yields and enantioenrichment. The redundancy of heating or high pressures allowed for chemoselective reduction with
Chew, Renta Jonathan, Wills, Martin
core +1 more source
Isoxazole is a five membered heterocyclic compound which is an azole with an oxygen atom next to nitrogen. The substituted isoxazole derivatives show various biological activities like antimicrobial, antiviral, anti-inflammatory, antioxidant, anticancer ...
Parul Setia, Ruchi Bharti, Renu Sharma
doaj +3 more sources
Synthesis of Some Fused Pyrazoles and Isoxazoles
The α-keto methylene group in 3,5-diaryl-2-cyclohexenones 2 and 3,5-diarylcyclohexanones 8 have been used to obtain fused pyrazoles and isoxazoles. The new compounds were characterized by IR and 1H-NMR spectral data.
Dandu Bhaskar Reddy+4 more
doaj +1 more source
Amides, anhydrides, esters, and thioesters of 2H-azirine-2-carboxylic acids were prepared by a rapid procedure at room temperature involving FeCl2-catalyzed isomerization of 5-chloroisoxazoles to 2H-azirine-2-carbonyl chlorides, followed by reaction with
Anastasiya V. Agafonova+2 more
doaj +1 more source