Results 31 to 40 of about 3,769 (135)

Combined experimental and theoretical studies of regio- and stereoselectivity in reactions of β-isoxazolyl- and β-imidazolyl enamines with nitrile oxides

open access: yesBeilstein Journal of Organic Chemistry, 2016
Reactions of β-azolyl enamines and nitrile oxides were studied by both experimental and theoretical methods. (E)-β-(4-Nitroimidazol-5-yl), (5-nitroimidazol-4-yl) and isoxazol-5-yl enamines smoothly react regioselectively at room temperature in dioxane ...
Ilya V. Efimov   +10 more
doaj   +1 more source

Environmental Toxicity Of Isoxazoline Drugs On Non-Target Species [PDF]

open access: yes, 2023
Lyme disease affects tens of thousands of people every year in the United States, causing serious illness and even death. It is caused by the bacterium, Borrelia burgdorferi, through infected black-legged tick bites. The range of these ticks is expanding,
Cooper, Haley M
core   +1 more source

Ultrasound Assisted One-Pot Synthesis of Novel 3-(Aryl)-5-((4-(phenyldiazenyl)phenoxy)methyl)isoxazolines in Water

open access: yesMolbank, 2022
In this work, we present an efficient one-pot method for the synthesis of three new azo-isoxazoline derivatives (4a–c) from aromatic aldehydes, hydroxylamine hydrochloride and 4-(allyloxy)azobenzene.
Ayoub El Mahmoudi   +3 more
doaj   +1 more source

Afoxolaner as a Treatment for a Novel Sarcoptes scabiei Infestation in a Juvenile Potbelly Pig

open access: yesFrontiers in Veterinary Science, 2020
A 2 months old female Vietnamese potbellied pig presented to a veterinary teaching hospital with a referring complaint of pruritus. A human caretaker of the pig had recently been diagnosed with a Sarcoptes spp. dermatitis.
Joe S. Smith   +6 more
doaj   +1 more source

Novel Quinazolinone–Isoxazoline Hybrids: Synthesis, Spectroscopic Characterization, and DFT Mechanistic Study

open access: yesChemistry, 2022
Quinazolinone and isoxazoline systems have attracted much attention due to their interesting pharmacological properties. The association of these two pharmacophores in a single hybrid structure can boost the biological activity or bring a new one ...
Yassine Rhazi   +7 more
doaj   +1 more source

A study on selective transformation of norbornadiene into fluorinated cyclopentane-fused isoxazolines

open access: yesBeilstein Journal of Organic Chemistry, 2021
This work presents an examination of the selective functionalization of norbornadiene through nitrile oxide 1,3-dipolar cycloaddition/ring-opening metathesis (ROM)/cross-metathesis (CM) protocols. Functionalization of commercially available norbornadiene
Zsanett Benke   +2 more
doaj   +1 more source

Glucose-derived spiro-isoxazolines are anti-hyperglycemic agents against type 2 diabetes through glycogen phosphorylase inhibition [PDF]

open access: yes, 2016
International audienceGlycogen phosphorylase (GP) is a target for the treatment of hyperglycaemia in the context of type 2 diabetes. This enzyme is responsible for the depolymerization of glycogen into glucose thereby affecting the levels of glucose in ...
Azay-Milhau, Jacqueline   +16 more
core   +2 more sources

Synthesis and Reactivity of Acyclic (pentadienyl)iron(1+) Cations: Model Studies for the Preparation of the 8\u3cem\u3eE\u3c/em\u3e,10\u3cem\u3eZ\u3c/em\u3e,16\u3cem\u3eE\u3c/em\u3e,18\u3cem\u3eE\u3c/em\u3e-Tetraene Segment of Macrolactin A [PDF]

open access: yes, 1999
The dicarbonyl(1,2-dimethylpentadienyl)triphenylphosphineiron(1+) cation (11) has been prepared from methyl 4-methyl-2E,4E-hexadienoate in four steps.
Donaldson, William   +2 more
core   +1 more source

A one-pot synthesis of 3-trifluoromethyl-2-isoxazolines from trifluoromethyl aldoxime

open access: yesBeilstein Journal of Organic Chemistry, 2013
Functionalized 3-trifluoromethyl-2-isoxazolines and 3-trifluoromethylisoxazoles were easily prepared from trifluoromethyl aldoxime 2 under mild conditions by using DIB as oxidant.
Raoni S. B. Gonçalves   +4 more
doaj   +1 more source

Mercury-Mediated Cyclization to 2-Isoxazolines [PDF]

open access: yes, 2022
The isoxazoline ring has been utilized in many therapeutic agents. For example, it is the key structure in ISO-1, an anti-inflammatory agent with unique anti-Type 1 diabetes activity.
Palmer, Abigail
core   +1 more source

Home - About - Disclaimer - Privacy