Results 51 to 60 of about 5,165 (157)

Electrochemical Dehydration Reaction

ChemSusChem, Volume 18, Issue 20, October 23, 2025.
Electrochemical dehydration reactions are a fascinating and underexplored field of research in the domain of electrosynthesis. They offer a sustainable alternative to hazardous and harsh dehydration reagents. In this review, the recent progress that has been made in this emerging research topic is surveyed.
Johannes Schneider, Enrico Lunghi, Siegfried R. Waldvogel   +2 more
wiley   +1 more source

Bicyclic Pyrrolidine-Isoxazoline γ Amino Acid: A Constrained Scaffold for Stabilizing α-Turn Conformation in Isolated Peptides

Frontiers in Chemistry, 2019
Unnatural amino acids have tremendously expanded the folding possibilities of peptides and peptide mimics. While α,α-disubstituted and β-amino acids are widely studied, γ-derivatives have been less exploited.
Francesco Oliva, Raffaella Bucci, Lucia Tamborini, Stefano Pieraccini, Andrea Pinto, Sara Pellegrino   +5 more
doaj   +1 more source

Mechanochemische Methoden mit Anwendung in der Late‐Stage Modifizierung Pharmazeutisch Wirksamer Verbindungen

Angewandte Chemie, Volume 137, Issue 41, October 6, 2025.
Dieser Review diskutiert mechanochemische Strategien zur späten Modifizierung bioaktiver Wirkstoffe und bietet zugleich eine wertvolle Übersicht zur Auswahl geeigneter Substrate, um das pharmazeutische Potenzial neuer und bestehender (mechano)chemischer Verfahren zu evaluieren.
Johanna Templ, Lars Borchardt
wiley   +1 more source

Synthesis and Study Biological Activity of Some New Isoxazoline and Pyrazoline derivatives

Ibn Al-Haitham Journal for Pure and Applied Sciences, 2017
   This work involves synthesis of novel Schiff bases derivatives contining isoxazoline or pyrazoline units starting with chalcons . 4-Aminoacetophenone was reacted with 3-nitrobenzaldehyde in basic medium giving chalcone [I] by claisen-schemidt ...
Muna S. Al-Rawi, Jumbad H. Tomma, Rana M. Abdullah   +2 more
doaj  

Mechanochemical Strategies Applied to the Late‐Stage Modifications of Pharmaceutically Active Compounds

Angewandte Chemie International Edition, Volume 64, Issue 41, October 6, 2025.
This review highlights mechanochemical strategies for the late‐stage modification of active pharmaceutical ingredients (APIs), providing a valuable resource for selecting substrates to evaluate the pharmaceutical potential of novel and existing (mechano)chemical protocols.
Johanna Templ, Lars Borchardt
wiley   +1 more source

Assessing the in Planta Efficacy of Oxathiapiprolin as a Potential Treatment for Kauri Dieback Disease

MicrobiologyOpen, Volume 14, Issue 5, October 2025.
We tested the oomycide oxathiapiprolin as a protective and curative agent against kauri dieback disease (caused by Phytophthora agathidicida) in Agathis australis seedlings. Protective application of oxathiapiprolin (10 or 50 mg per seedling) effectively prevented disease, but it did not cure existing infections.
Hannah F. Robinson, Jade T. T. Palmer, Monica L. Gerth   +2 more
wiley   +1 more source

The Azidofunctionalization of Alkenes

ChemistryEurope, Volume 3, Issue 5, September 18, 2025.
The azidofunctionalization of alkenes offers a powerful strategy for synthesizing nitrogen‐containing compounds by installing both an azide and a second functional group in one step. This approach, employing photoredox catalysis, transition metals, and radical methods, is efficient, selective, and versatile, with applications in pharmaceuticals and ...
Pierre Palamini, Jerome Waser
wiley   +1 more source

An Unexpected Formation of Spiro Isoxazoline-Dihydrofurane Compounds from Substituted Ketofurfuryl Alcohols

Molecules
Oximation of substituted ketofurfuryl alcohols in the presence of hydroxylamine hydrochloride and pyridine in ethanol as solvent led to a new class of spiro derivatives presenting a 7-methylene-1,6-dioxa-2-azaspiro [4.4] nona-2,8-diene skeleton along ...
Claire Cuyamendous, Mathieu Yves Laurent, Christine Saluzzo   +2 more
doaj   +1 more source

Kupfer(II)‐photokatalysierte Radikalannellierung von Nitroalkanen mit Alkenen oder Alkinen zur Synthese von Isoxazolinen und Isoxazolen

Angewandte Chemie, Volume 137, Issue 37, September 8, 2025.
Wir stellen ein Cu(II)‐photokatalytisches Verfahren vor, bei dem handelsübliche Nitroalkane für die Synthese von Isoxazolinen und Isoxazolen aus Alkenen bzw. Alkinen verwendet werden. Detaillierte mechanistische Untersuchungen ergaben, dass der breite Substratbereich, der sowohl aktivierte als auch nicht aktivierte Alkene und Alkine umfasst, auf einen ...
Sunaina Sardana, Aryaman Pattanaik, Julia Rehbein, Oliver Reiser   +3 more
wiley   +1 more source

Ultrafine Bubbles (UFB) Alleviate Toxicity of Fluxametamide‐Based Insecticides to Nontarget Freshwater Species, Daphnia magna

Environmental Quality Management, Volume 35, Issue 1, Fall 2025.
ABSTRACT Pesticide contamination in freshwater ecosystems poses a significant threat to water quality and aquatic life, potentially disrupting entire food webs. Fluxametamide (FMT), a novel insecticide regarded as safe for nontarget species, has not been extensively studied in aquatic environments, raising concerns about its potential toxicity to ...
Desty Pratiwi, Takasaki Hironori, Yosuke Sawada, Kenji Kamura, Sunardi Sunardi, Takeshi Fujino   +5 more
wiley   +1 more source